Sentences with phrase «key enzymes in»

Insulin activates key enzymes in pathways, which store energy derived from carbohydrates, and when there is an absence or scarcity of dietary carbohydrates the resulting reduced insulin level leads to a reduction in lipogenesis and fat accumulation.

Branched - chain amino acids activate key enzymes in protein synthesis after physical exercise.

Blomstrand, E. Branched - chain amino acids activate key enzymes in protein synthesis after physical exercise.

Biotin is an essential cofactor for several key enzymes in the production and metabolism of glucose, fat, and protein.

Carbonic Anhydrases (CAs) are key enzymes in coral physiology.

Inhibit key enzymes in cancer cell specific metabolic pathways to disrupt tumor cell proliferation and survival

A 2012 Swinburne study looked at how some of these extracts slow down two key enzymes in carbohydrate metabolism which affect blood sugar and diabetes and also found they had an antioxidant effect.

The Surolias went on to show that, like in bacteria, triclosan is the wrench that jams Plasmodium's fatty acid machinery; it inhibits one of the key enzymes in the biochemical conveyor belt.

In collaboration with the University of Texas Southwestern Medical Center (UTSW) in Dallas, the researchers found that the tumor - suppressive activity of geranylgeraniol was accompanied by down - regulation of HMG CoA reductase, a key enzyme in the mevalonate pathway that provides essential intermediates for the posttranslational modification of growth - related proteins such as Ras, nuclear lamins and insulin - like growth factor receptors.

Its complex three - dimensional structure allows it to act simultaneously on two parts of a key enzyme in the tuberculosis bacillus, and in doing so, dramatically reduce the risk that the bacteria will develop multiple resistances.

Dalli and his colleagues found that people with heart disease lack a key enzyme in their monocytes and neutrophils so they can not make resolvins as easily.

Glyceraldehyde -3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D - glyceraldehyde 3 - phosphate (G3P) into 3 - phospho - D - glyceroyl phosphate.

HIBM is caused by mutations in the gene encoding the key enzyme in sialic acid synthesis, UDP - GlcNAc 2 - epimerase / ManNAc kinase, which in turn leads to sialic acid deficiency.

Studying heparanase - a key enzyme in the development and metastasis of human cancers — scientists unveiled new fluorescent imaging agents that detect enzyme activity in healthy and diseased tissues.

«It inhibits tyrosinase, which is the key enzyme in pigment production, through its interaction with copper,» helping skin look brighter.

For example, not only do they block HMG coenzyme A reductase (a key enzyme in cholesterol synthesis), they also block Coenzyme Q10.

This is a key enzyme in the adrenal gland which converts cholesterol into cortisol.

ACC is a key enzyme in a process called lipogenesis — the creation of fat.

Statins such as Lipitor, Zocor, Pavacol and Mevacor lower cholesterol by inhibiting HMG - CoA reductase, a key enzyme in cholesterol synthesis.

A key enzyme in cholesterol biosynthesis is 3 - hydroxy -3-methylglutaryl — CoA reductase (the target for statins), which is activated by insulin, which means that an increase in blood glucose and consequently of insulin levels will lead to increased endogenous cholesterol synthesis.

Monoamine oxidase A (MAOA) is a key enzyme in the catabolism of monoamines, especially serotonin.

Not exact matches

This hearty vegetable activates and regulates detoxification enzymes in the body from the key phytonutrients and antioxidants.

Enzymes are key in the production of partially hydrolyzed whey infant formula for babies who have allergies or intolerances to cow's milk proteins.

They are carefully germinated to activate enzymes that result in the increased availability and digestibility of key nutrients.

The key thing is to prevent oxygen coming into contact with enzymes in the product, as that causes discolouration.

However, the impact of the two methylation - regulating enzymes was still seen at 10 to 15 months, when scientists found decreased expression of hundreds of genes — many of which are key tumor suppressor genes such as BMP3, SFRP2 and GATA4 — in the smoke - exposed cells and a five - or - more-fold increase in the signaling of the KRAS oncogene that is known to be mutated in smoking - related lung cancers.

The key to a better sensor is maintaining a large amount of enzyme activity for detecting antigens in a sample.

A digestive enzyme called salivary amylase plays a key role in breaking down starch into simple sugars so it can be absorbed in the gut.

The researchers have built upon this breakthrough to design a way to «outsmart Mother Nature,» Peersen said, by reengineering one key part of the polymerase enzyme so the virus can't grow very rapidly in a cell.

A particular enzyme in the pathway — phosphogluconate dehydrogenase (PGD)-- turned out to be key, enabling the conversion of glucose to metabolites that «can directly fuel tumor growth,» McDonald said.

The enzyme is produced by white blood cells called neutrophils, which play an important role in inflammatory and immune responses and may be a key contributor to the development of muscular dystrophy.

Now, Yale University pulmonary specialist Jack Elias and his colleagues have tied a second chitinase, an enzyme called acidic mammalian chitinase, to a key inflammatory response in asthma.

Using the same computer - based approach, the team has now been able to target the c - FLIP (cellular FLICE [FADD - like IL - 1β - converting enzyme]- inhibitory) protein, known to play a key role in cancer stem cell maintenance and survival, described in previously published work by the Institute.

The key to immortalization is an enzyme called telomerase, which keeps chromosomes healthy in cells that divide frequently.

In a new study, researchers demonstrate that the enzyme FIH (Factor Inhibiting HIF) is a key to how this switch - over happens.

Comparing proteins produced by normal genes to those produced by mutant Bt resistant ones, the team discovered that enzymes play a key role in determining whether or not a worm succumbs to the toxin.

An international research team identifies for the first time a key enzyme for the synthesis of glycoconjugates (sugars linked to other molecules) in Plasmodium falciparum and other intracellular parasites belonging to the large phylum Apicomplexa.

Scientists have captured atomic level snapshots showing how one key enzyme modifies a protein involved in turning genes on or off inside cells.

«Scientists determine structure of enzyme linked with key cell - signaling protein: Findings aid understanding of how modifications to cell - signaling protein affect its action in turning genes on and off.»

«Our study shows, for the first time, in human skin that with increasing age there is a specific decrease in the activity of a key metabolic enzyme found in the batteries of the skin cells.

Crizotinib is a drug agent that takes aim at key enzymes within cells called kinases, which are often abnormal in cancer.

Techniques were used to measure the activities of the key enzymes within mitochondria that are involved in producing the skin cell's energy, a type of mitochondrial gym or skin physical.

For the first time, scientists at Newcastle University, UK, have identified that the activity of a key metabolic enzyme found in the batteries of human skin cells declines with age.

Violaxanthin de-epoxidase (VDE) is the key enzyme responsible for this process, which kicks into gear in the presence of excess light.

Hancock's group showed that inhibiting the enzyme p300 can affect the functions of another protein, Foxp3, which plays a key role in controlling the biology of Tregs.

Beta - hydroxy - beta - methylbutyrate (HMB) is a metabolite of leucine, a branched - chain amino acid found in whey protein that activates key protein synthesis enzymes post-exercise.

UC attorneys have argued that the move from prokaryotes to eukaryotes was obvious, and insisted that Zhang's lab's subsequent refinement of a key component in the CRISPR system — a variation of an enzyme known as Cas9 — also was obvious.

As reported in the journal Angewandte Chemie, this drug blocks key enzymes used in mycomembrane biosynthesis, significantly increasing the effectiveness of conventional antibiotics.

The key appears to be a single zinc atom that sits at the core of the enzyme, which resembles a pyramid in structure.

Scientists at the University of York are playing a key role in the quest for a better understanding of how a recently discovered family of enzymes can degrade hard - to - digest biomass into its constituent sugars.