Sentences with phrase «key features of disease»

Emergence and evolution of TP53 mutations are key features of disease progression in myelodysplastic patients with lower - risk del (5q) treated with lenalidomide

This intricate control may underlie key features of the disease

Not exact matches

A key feature of STB is the long symptomless growth of the fungus — called Zymoseptoria tritici — which can affect the host plant's cells before it switches to the visible disease phase that eventually destroys the plant's leaves.

In a race with other scientists, Scottish researchers have bred mice with an altered gene which displays all the key features of cystic fibrosis, such as lung disease and digestive problems.

Prof. Jean - Christophe Marine (VIB - KU Leuven) and others developed mouse models recapitulating some of the key histopathological features of the human disease.

This type of structural flexibility, called conformation entropy, is also a key feature in other peptides that form toxic plaques in diseases such as Huntington's disease, Type 2 diabetes, and Parkinson's disease.

«This is an exciting new tool to answer important questions about proteins,» Cochran said, likening µSCALE to the way that high - throughput tools for gene analysis have allowed researchers to unlock key features of biology underlying human disease.

In addition, neuronal damage and death are key features of the pathophysiology of age - related neurological diseases including Alzheimer's and Parkinson's disease.

Decline in mitochondrial form and function are widely recognized but poorly understood features of aged cells, and key features of aging - related diseases such as Parkinson's and Alzheimer's.

«The NFT is thought to be more closely related to memory decline than other forms of aging - related pathologies, but there are still very few genes that have been implicated in the accumulation of this key feature of Alzheimer's disease and other brain diseases.»

This session will focus on skeletal dysplasias as a model for rare genetic diseases, highlighting tools for collecting natural history data and healthcare needs data; key diagnostic clinical and molecular features; and management, including novel emerging disease - modifying treatments based on better understanding of molecular pathogenesis.

Because the fly modeled the key features of the human disease, researchers can now screen proteins and molecules quickly to see which might have therapeutic effects.

The new study found that T cells can be tricked into thinking dopamine neurons are foreign by the buildup of damaged alpha - synuclein proteins, a key feature of Parkinson's disease.

Taken together, these results demonstrated that disease - specific human iPS cell — derived hepatocytes are capable of modeling key pathological feature of A1ATD in vitro and may also prove useful for future drug screening assays.

A key feature of this bestseller, and of Robison's stance toward Asperger's in general, is that being on the autism spectrum is a gift rather than a disease.

Other topics featured during these events included: Advances in Canine Cancer Progressive Retinal Atrophy Gastric Dilation - Volvulus (Bloat), and Tick Talk This was our second year hosting this type of event and again it was an overwhelming success in terms of the numbers of people that joined us and spent time learning about key initiatives the Foundation is currently working on, as well as the face to face conversations with Foundation board members, Dr. Diane Brown and volunteers who had personal experiences caring and managing dogs afflicted by some of these diseases.

Key works include Andrew Erdos's Texture of a Ghost (2011), a 6 x 8 foot room featuring hand - blown glass sculptures and a video installation; Josiah McElheny's Landscape Model for Total Reflective Abstraction (I)(2004); Luke Jerram's E. coli (2010), which explores the tension between scientific objectivity and cultural perceptions of viruses, diseases, and bacteria; twelve snow globes by Walter Martin and Paloma Muñoz from the Travelers series; three stained glass light boxes by Judith Schaechter; and a recent body of work by Czech Republic - based artist Karen LaMonte that highlights the role of the kimono in Japanese culture.

In doing so, I had joined two of the key features of AA that account for its dismal failure to arrive at prompt, full recovery, (1) the group format that allows fellowships of addiction to emerge as surrogate families, and (2) the clinical mindset of the psychological disease concept of addiction that views self - intoxication by problem drinkers and drug addicts as an innocent act committed by innocent individuals.