Sentences with phrase «key gene changes»

However, another strain of E. coli has several key gene changes that can cause severe food poisoning if it enters the gut.

Not exact matches

Together, these experiments show that the PERIOD3 gene likely plays a key role in regulating the sleep - wake cycle, influencing mood and regulating the relationship between depression and seasonal changes in light availability, the team reports today in the Proceedings of the National Academy of Sciences.

Changes in key genes clearly define four previously unknown conditions within the umbrella diagnosis of schizophrenia, according to a study led by researchers from NYU Langone Medical Center published online April 28 in EBioMedicine, a Lancet journal.

«U1 dysfunction might produce changes in RNA processing affecting many genes or specific changes affecting a few key genes that are important in Alzheimer's,» Lah says.

Tattersall explains how epigenetic effects on key genes cascade to produce radical morphological changes in an eye blink, and why our unusual thinking style, far from being the perfected product of long - term selective pressures, was bootstrapped out of existing abilities barely 100,000 years ago.

In addition to its effect on the insulin pathway, the let - 7 microRNA appears to drive these metabolic and functional changes by acting on other key gene regulators.

Alternatively, epigenetic changes — changes in the way genes are switched on and off — influencing key genes, induced by sex hormones, may be responsible.

After analyzing brain tissue samples, the researchers identified an area of the gene where a single change reduced BDNF levels in the hypothalamus, a key area that controls eating and body weight.

Analysis of daily gene activation in a patient with severe Ebola virus disease cared for at the National Institutes of Health (NIH) in 2015 found changes in antiviral and immune response genes that pinpointed key transition points in the response to infection.

For instance, they discovered that ppGpp - mediated effects are the key to understanding constitutive gene expression under environmental changes, including both nutrient and antibiotic changes.

Curiously, this genetic change triggered, millions of years later, the connection between two gene regulatory networks (those controlled by ESRP and by Fgfr), which became key for the origin of many vertebrate organs and structures (lungs, forelimbs and inner ear).

The color - coded list identifies documented mutations in key viral genes, along with literature citations and a description of how the mutation is believed to change biological function.

The Gladstone team had profiled changes in gene expression using DNA microarrays, which provides an unbiased method for identifying key biological pathways.

By determining how changes in gene expression affect the fate of glial cells in mice, we hope to understand the key factors that govern neural cell regeneration in the human brain.

In 2012, Dr. Yamanaka was awarded the Nobel Prize in Physiology or Medicine for his discovery that skin cells can be reprogrammed into pluripotent stem cells by changing just four key genes.

«In addition to lending support to the idea that changes in gene regulation are a key part of our evolutionary history, these new results help to define exactly which regulatory factors may be important, at least in certain tissues.

We are also not yet able to accurately detect changes in key regions of the Plasmodium genome including, for example, the hypervariable var genes, which contribute to the parasites» ability to evade our immune system.

We now know that changes in methylation state also have key roles in influencing gene expression,» Mullighan said.

In these articles, I discuss at length the 5R's as a road map to fixing the cell and why they offer the key to changing what your genes are expressing.

Grant 1557: High - Resolution Cytogenetic Analysis of Histiocytic Malignancies and Development of a Targeted Assay to Screen for Expression Level Changes Dr. Matthew Breen, PhD Project Goal: The goal of this project is to narrow down the search for genes playing a key role in Histiocytic Malignancies and thus move a step closer to developing targeted therapies for canine patients diagnosed with this devastating cancer.