Sentences with phrase «key gene for»

Although the experiment would be very difficult to pull off in a non-model organism, «that would be the real kicker to demonstrate that that is the key gene for it,» he said.

Study Dispels Theories of Y Chromosome's Demise: Stripped - Down Chromosome Retains Key Genes for Fertility

The researchers found that MYC may affect circadian rhythm and metabolism by promiscuously binding to promoter regions in key genes for maintaining these daily cycles.

Not exact matches

In sum, we believe in hiring and mentoring talented people who have the «collaboration gene» — and that it is a key requirement for success at MFS.

By invalidating key parts of Myriad's patents, the court has removed a bar that prevented labs using new technology from developing and selling broader one - time tests that search for all known cancer risks, including the BRCA genes, geneticists said.

Some researchers have proposed deleting or disabling key genes that are required for early embryonic development.

«The advantage of being able to adjust a set of genes identified as key autism risk factors may explain the strong and long - lasting efficacy of this therapeutic agent for autism.»

Now her team has analysed the immune system's key controller genes for the first time and found that resistant devils have genes that equip them to attack the disease (Proceedings of the Royal Society B, DOI: 10.1098 / rspb.2009.2362).

The key insight for building such drugs came to Tim Tully, founder and chief science officer of Helicon, when his team at Cold Spring Harbor Laboratory on Long Island stumbled upon the molecular switch: a gene called CREB, which is involved in converting short - term memories into long - term ones.

Building the knowledge base requires humans to teach computers key concepts from curated articles; with modest online training, anyone who reads English can scan research papers for key terms — names of genes, proteins, diseases, and drugs — and use online marking tools to document relationships between them (for example, drug X treats disease Y).

A team of researchers at the Stanford University School of Medicine has used a gene - editing tool known as CRISPR to repair the gene that causes sickle cell disease in human stem cells, which they say is a key step toward developing a gene therapy for the disorder.

For the first time, the response of more than 10,000 genes was followed simultaneously, which identified brassinosteroids and auxins and their signalling molecules as key to the growth stimulation observed in biochar.

The team sequenced the gene that codes for the NaV1.7 channel in mole rats, and compared it with SCN9A — a key gene in the human version of the channel.

A second key gene, SLC39SA13, codes for a zinc transporter that helps nerve cells to «decide» whether or not nerve impulses are amplified of dampened.

One key gene encodes the making of a receptor called TREM2, a docking site for molecules on the surface of microglia and other innate immune cells.

The new and improved wheat assembly will help wheat breeders accelerate their crop improvement programmes and researchers to discover genes for key traits such as yield, nutrient use and bread making quality.

«Stem cell gene therapy could be key to treating Duchenne muscular dystrophy: Approach developed at UCLA holds promise for 60 percent of patients with the deadly disease.»

The key objective was to see how exam scores varied from the national average depending on whether twins had the same genetic make - up, as identical twins do, or shared only half of their genes, which is true for non-identical twins.

The second gene, TNFRSF6B, encodes a receptor related to those that bind tumor necrosis factor (TNF)-- a key chemical signal for triggering inflammation in IBD as well as in patients with other autoimmune disorders such as rheumatoid arthritis and psoriasis.

The mutation, in a gene called HTR2B, prevents production of the serotonin 2B receptor, a key docking point in brain cells for the neurotransmitter serotonin.

A key challenge is that, at least in developed countries, deaf people tend to marry each other, thus mingling many genes for impaired hearing.

Genomics - based discovery is key for identifying genes of potential interest to plant breeders and biotech seed developers.

It took months, for instance, for researchers to obtain key blueprints, video footage, and samples from scrap steel beams, said W. Gene Corley, head of a government - sponsored study team organized by the American Society of Civil Engineers.

Infants were also screened for mutations in the filaggrin (FLG) gene, which codes for a key skin barrier protein.

The results from McCammon's initial screen with zebrafish indicate that two genes in the 16p11.2 region could be key for brain development: fam57ba and doc2a.

She notes that a few of the genes the team identified code for glutamate receptors, which play a key role in learning and memory and may have been selected in humans as well.

For instance, one protein produced by a key fruit fly gene serves two separate functions over the course of fly development.

«Now that we know how calcification happens and what the key nodes are, we know what genes to look for that might be mutated in other related forms of cardiovascular disease.»

This understanding of cancer's evolution has key implications for treatment, he noted, «In addition to pointing out that we will need to target driver genes that are mutated early in cancer, this evolutionary approach provides a method that accurately characterizes which genes are being mutated early and late.

With the acquisition of a number of key genes and lipids from a bacterial symbiont, it would be possible for Loki - type cells to evolve a primitive membrane trafficking machinery and compartmentalization.»

«Because many broadly expressed genes that play key roles in essential cellular functions are under the control of cell - specific enhancers, the ability to affect enhancer function by knocking down eRNAs could potentially provide a new strategy for altering gene expression in vivo in a cell - specific manner,» said Glass, noting that in his research, anti-sense oligonucleotides were developed in conjunction with Isis Pharmaceuticals, which suppressed enhancer activity and reduced expression in nearby genes.

Years of diabetes research carried out on mice whose DNA had been altered with a human growth hormone gene is now ripe for reinterpretation after a new study by researchers at KU Leuven confirms that the gene had an unintended effect on the mice's insulin production, a key variable in diabetes research.

By flipping on three key genes in cells from the lower stomach, scientists may have engineered a viable replacement for those beta cells.

A new method has been found for identifying therapeutic targets in cancers lacking specific key tumor suppressor genes.

With the completion of the first phase of the Human Genome Project in 2000, and the advent of sequencing technologies that can detect gene variations such as single nucleotide polymorphisms (SNPs), for the first time scientists have the tools in hand to find the key immune genes and genetic networks that play roles in vaccine response.

Kriegstein notes that the hunt will likely commence for small molecules capable of activating the key genes.

This is key to using CRISPR for gene therapy to, say, repair a mutation that causes sickle cell anemia or hemophilia.

They found what they were looking for on the CNGA3 gene, which encodes a cyclic nucleotide channel and plays a key role in transducing visual signals.

Similar to a key that fits a lock, the scissors only fit a specific pattern of gene fragments that may serve as a genetic fingerprint for the species searched.

Another key issue for our clients is the fate of patents covering human genes.

Germany's Max Delbrück Center for Molecular Medicine (MDC) Berlin Buch and the Fu Wai Hospital of the Chinese Academy of Medical Sciences (CAMS) are building a new gene research laboratory in Beijing, the aim being to identify genes that play a key role in the pathogenesis of cardiovascular diseases.

These genes could have been the key for turning wild animals into more docile domesticated forms.»

The study reveals that the mutated gene affects a key housekeeping process that is required for removing unwanted molecules from cells in the body.

Analysis of daily gene activation in a patient with severe Ebola virus disease cared for at the National Institutes of Health (NIH) in 2015 found changes in antiviral and immune response genes that pinpointed key transition points in the response to infection.

A key cancer - causing gene, responsible for up to 20 percent of cancers, may have a weak spot in its armor, according to new research from the Masonic Cancer Center, University of Minnesota.

«We did not find any evidence for [key] domestication genes,» he concluded.

There are even a few islands — those that contain genes involved in behavior and size, key traits for domesticated animals — that are in the genomes of both European and Asian pigs, Larson reports.

Rhythmic expression of key genes is essential for maintaining proper timekeeping of the body's clock.

«Cell biologists discover on - off switch for key stem cell gene.»

The Jan. 12 issue of the journal Science provides an in - depth and timely review of the key developments that have led to several successful gene therapy treatments for patients with serious medical conditions.