Sentences with phrase «key genes»

A new technique can determine if a chemical has the potential to activate key genes in seconds rather than the typical 24 hours or more.

The data allowed the researchers to generate personalized genome - scale metabolic models for cancer patients to identify key genes involved in tumor growth.

It was assumed that these fish became blind because mutations disabled key genes involved in eye development.

Alternatively, epigenetic changes — changes in the way genes are switched on and off — influencing key genes, induced by sex hormones, may be responsible.

Previous studies have highlighted the similarities among key genes in fruit flies and people.

Some of the letter variants were inside a gene, while others were near key genes.

By flipping on three key genes in cells from the lower stomach, scientists may have engineered a viable replacement for those beta cells.

Some researchers have proposed deleting or disabling key genes that are required for early embryonic development.

This study generated more than 5 million datapoints, information that led to the identification of key genes indicative of responsiveness to glucocorticoids.

«Scientists discover key gene for producing marine molecule with huge environmental impacts.»

Although it's long been known that the kidneys play a part in blood pressure control, this study identified key genes involved in the process through comprehensive and large gene expression analysis of the kidneys.

Tattersall explains how epigenetic effects on key genes cascade to produce radical morphological changes in an eye blink, and why our unusual thinking style, far from being the perfected product of long - term selective pressures, was bootstrapped out of existing abilities barely 100,000 years ago.

Indiana University scientists have discovered the first known instance of a plant or animal lacking several key genes involved in energy production in cells.

According to Beg, NF - κB proteins regulate key genes involved in immune response, inflammation, cell death and cell growth.

The susceptibility of German shepherds to chronic diarrhoea is not due to a failure of transcription of key genes encoding molecules involved in mucosal IgA secretion In collaboration with scientists at the University of Bristol, UK, WALTHAM investigated a potential cause of the susceptibility of German shepherd dogs to chronic diarrhoea (Peters et al. 2005).

«What we observed is that the levels of many miRNAs change significantly throughout the 48 - hour period following a blood meal, indicating that these miRNAs, in turn, may be establishing significant changes in expression of key genes during this time in the fat body,» said Fedor V. Karginov, an assistant professor of cell biology and neuroscience, who co-led the research team along with Alexander S. Raikhel, a distinguished professor of entomology at UC Riverside.

Scientists have now sequenced the genome of the Mexican axolotl, and have identified a few key genes hidden amongst its extremely complex genetic blueprint that shed some light on its remarkable regeneration capabilities.

Matthew Dyson, research assistant professor of obstetrics and gynecology at Northwestern University Feinberg School of Medicine and and Serdar Bulun, MD, chair of obstetrics and gynecology at Feinberg and Northwestern Memorial Hospital, also identified a novel role for a family of key gene regulators in the uterus.

The DNA variation observed at key genes revealed a large diversity of coat coloration patterns within Scythian horses, including bay, black, chestnut, cream and spotted animals.

After several rounds of validation, functional classification and gene expression analysis, we have identified key genes likely to be involved in CD1d antigen presentation.

SOX2 is one of two key genes researchers use to generate induced pluripotent stem cells (iPSCs), which are capable of differentiating into all cell types for research and potential therapeutic applications.

Researchers from North Carolina State University have developed a high - throughput technique that can determine if a chemical has the potential to activate key genes in seconds rather than the typical 24 hours or more.

However, another strain of E. coli has several key gene changes that can cause severe food poisoning if it enters the gut.

For Chris Wozniak of EPA's Office of Pesticide Programs in Washington, D.C., the uncharted territory is RNA interference — a process of exposing weeds or insects to engineered, double - stranded RNA molecules that silence key genes by disrupting a cell's ability to translate them into proteins.

Study Dispels Theories of Y Chromosome's Demise: Stripped - Down Chromosome Retains Key Genes for Fertility

Changes in key genes clearly define four previously unknown conditions within the umbrella diagnosis of schizophrenia, according to a study led by researchers from NYU Langone Medical Center published online April 28 in EBioMedicine, a Lancet journal.

A second key gene, SLC39SA13, codes for a zinc transporter that helps nerve cells to «decide» whether or not nerve impulses are amplified of dampened.

Researchers have found that the expression of three key genes drops during the fasting - mimicking diet.

While the findings demonstrate how altering the expression of a single key gene can make a big difference to brain development, a future challenge will be to obtain a comprehensive, integrated view of all the molecular changes that made our brains big.

They showed that NDP1 bioactivity governs key gene interactions decisive in cell survival when threatened by disease or injury.

In addition to its effect on the insulin pathway, the let - 7 microRNA appears to drive these metabolic and functional changes by acting on other key gene regulators.

The authors conclude that the study of marine mammals is just the first demonstration of this new evolutionary approach, and is versatile enough to be applied to many other emerging questions concerning key genes involved in the diversity of life.

In 1972, he devised a now widely used formula, Nei's standard genetic distance, which compares key genes of different populations to estimate how long ago the groups diverged.

This caused two key genes normally activated solely on the left side of the body to be expressed on the right side, the team reports in the 4 July issue of Nature.

Bert Vogelstein and Kenneth Kinzler, who co-direct a lab at the Johns Hopkins University medical campus, helped lay the foundation of cancer genetics by revealing how mutations in key genes lead to a tumor.

During the 1990s, a team led by Jeffery Taubenberger at the Armed Forces Institute of Pathology in Washington, D.C., sequenced key gene fragments of the 1918 flu strain, recovered from frozen victims found in the Alaskan permafrost and in archived autopsy material.

His lab initially tried making the virus more transmissible in ferrets — virologists» preferred animal model — by mutating key genes.

There is no way to change people's sexuality, but if key genes are found, it might be possible to detect homosexuality before birth, or to «cure» people by altering those genes.

Professor Frédéric Veyrier's most recent research, in collaboration with the team of Professor Hilde De Reuse at the Institut Pasteur, has shed light on key genes essential to the pathogenesis of Helicobacter pylori bacterium, which causes gastric infections.

Next, in mouse studies, the scientists deleted key genes, called Atg7 or Atg5, whose function was necessary for autophagy in regulatory T cells.

Cook's illustrious subjects include the umbrella - bearing British cosmologist Sir Martin Rees of the University of Cambridge, the wrinkle - faced late naturalist and flea expert Miriam Rothschild, and the biologist Christiane Nüsslein - Volhard (left) of the Max Planck Institute for Developmental Biology in Tübingen, Germany, who won the 1995 Nobel Prize in Physiology or Medicine for codiscovering key genes that shape embryonic development.

When the research team used pharmaceuticals to inhibit one function of the endoplasmic reticulum (the building of so - called lipoprotein particles that will export fats out of the cell), the gene activation process was inhibited for many key genes and nuclear ruffling was also altered.

This technology is based on differential expression of key gene transcript variants (isoform - level gene expression) and was originally tested on a vast collection of glioblastoma samples made available by the University of Pennsylvania.

The aim of this study is to identify potential key genes and pathways that are related to the calcification apparatus.

Novak and his team are studying DNA from taxidermied museum specimens and planning to insert key genes into the genomes of band - tailed pigeons.»

Bisphenol A affects amelogenesis by modulating enamel key genes expression.

Drug developers, meanwhile, are exploring compounds that may be capable of thwarting epigenetic modifications that cause key genes to become under - or overactive, thereby promoting cancer and other diseases.