Sentences with phrase «key genes encoding»
The susceptibility of German shepherds to chronic diarrhoea is not due to a failure of transcription of key genes encoding molecules involved in mucosal IgA secretion In collaboration with scientists at the University of Bristol, UK, WALTHAM investigated a potential cause of the susceptibility of German shepherd dogs to chronic diarrhoea (Peters et al. 2005).
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One key gene encodes the making of a receptor called TREM2, a docking site for molecules on the surface of microglia and other innate immune cells.
Not exact matches
Biologists now know that the genome sequence holds only a small part of the answer, and that key elements of development and disease are controlled by the epigenome — a set of chemical modifications, not encoded in DNA, that orchestrate how and when genes are expressed.
The second gene, TNFRSF6B, encodes a receptor related to those that bind tumor necrosis factor (TNF)-- a key chemical signal for triggering inflammation in IBD as well as in patients with other autoimmune disorders such as rheumatoid arthritis and psoriasis.
They found what they were looking for on the CNGA3 gene, which encodes a cyclic nucleotide channel and plays a key role in transducing visual signals.
But a new report published today in Current Biology reveals that genes that encode key hair - building proteins are also present in reptiles and birds.
«Our findings show that the parts of genes that we think of as being silent actually encode very key functional information.»
In rice, Oryza sativa HOMEOBOX1, a key regulator of meristem maintenance similar to kn1 from maize, controls local BR accumulation by directly targeting and upregulating genes encoding BR catabolism and conjugation enzymes (Tsuda et al., 2014).
HIBM is caused by mutations in the gene encoding the key enzyme in sialic acid synthesis, UDP - GlcNAc 2 - epimerase / ManNAc kinase, which in turn leads to sialic acid deficiency.
Rather it is the definition of those key genes that encode the targets for intervention in disease.