Sentences with phrase «key genes in»

Researchers from North Carolina State University have developed a high - throughput technique that can determine if a chemical has the potential to activate key genes in seconds rather than the typical 24 hours or more.

They demonstrate that shutting down key genes in the initiation of the process allows the worms to live longer compared with leaving it running crippled.

A new technique can determine if a chemical has the potential to activate key genes in seconds rather than the typical 24 hours or more.

By flipping on three key genes in cells from the lower stomach, scientists may have engineered a viable replacement for those beta cells.

In recent years, clock researchers have uncovered some of the gears and springs that keep this circadian timepiece running, largely by identifying a handful of key genes in organisms from bread mold to mice.

Upon joining the lab, Lee chose a high - risk project — «it sounded like more fun,» she says — aimed at determining whether a key gene in the yeast cell cycle, cdc2, was also present in human cells.

The team sequenced the gene that codes for the NaV1.7 channel in mole rats, and compared it with SCN9A — a key gene in the human version of the channel.

By isolating a key gene in the remaining plants, scientists found the receptor that aids in plant development and helps repair a plant during major events.

They had identified a key gene in the beet cyst nematode that makes the cytokinin hormone.

«Key gene in early brain regeneration in planarians described by scientists.»

Therefore, egr - 4 is a key gene in early brain regeneration.

Nevertheless, our data clearly point to ANKRD55 as the key gene in this area.

In a separate paper, virologist Mark Gibbs and his colleagues at Australian National University in Canberra report that a key gene in the virus that caused the 1918 pandemic is part pig, part human.

Not exact matches

In other words, these four genes likely play a key role in the biology of the disordeIn other words, these four genes likely play a key role in the biology of the disordein the biology of the disorder.

Many genetic tendencies don't exist in isolation; the key is to understand how multiple genes interact.

Spark Therapeutics (ONCE)- The $ 2 billion gene therapy pioneer has over a quarter of its market capitalization in cash, a key ex-US partnership with Novartis (NVS)(can leverage its infrastructure plus adds credibility to LUXTURNA prospects), and pipeline of promising assets with several opportunities to create value in 2018.

In sum, we believe in hiring and mentoring talented people who have the «collaboration gene» — and that it is a key requirement for success at MFIn sum, we believe in hiring and mentoring talented people who have the «collaboration gene» — and that it is a key requirement for success at MFin hiring and mentoring talented people who have the «collaboration gene» — and that it is a key requirement for success at MFS.

One of the key caveats at the time, however, was that the technique required the use of a virus to introduce several genes into the skin (or other) cell, and these would remain in the cell, and so might contaminate the resulting stem cell or create cancer risks.

However, this first phase fairly rapidly was superseded by a second, in which Sewall Wright and Theodosius Dobzhansky were the two key figures, both of them insisting on the importance of thinking of populations of many genes, as well as populations of many individuals.

I think everyone who hates Thanksgiving leftovers should be rounded up in a room, door locked, and the key thrown away to prevent them from spreading their gene pool, haha!

Two key components come into play in coeliac disease: genes and environmental factors.

Other factors such as hormones and genes also cause hair loss, but the key factor is the deficiency in nutrients.

Following this in 2015, an article (Alsaweed et al.) described over 300 novel milk microRNA molecules, components that are known to play a key role in the regulation of gene expression.

We identify key candidate genes that may control rate - limiting steps during lactation and outline future work in the endeavor to discover the biological underpinnings of poor lactation performance in women attempting to breastfeed.

We observed strong modulation of key genes involved in lactose synthesis and insulin signaling.

However, the impact of the two methylation - regulating enzymes was still seen at 10 to 15 months, when scientists found decreased expression of hundreds of genes — many of which are key tumor suppressor genes such as BMP3, SFRP2 and GATA4 — in the smoke - exposed cells and a five - or - more-fold increase in the signaling of the KRAS oncogene that is known to be mutated in smoking - related lung cancers.

That entailed, among other things, splicing in rat genes that direct the production of dopamine, a key intermediate in noscapine synthesis.

Together, these experiments show that the PERIOD3 gene likely plays a key role in regulating the sleep - wake cycle, influencing mood and regulating the relationship between depression and seasonal changes in light availability, the team reports today in the Proceedings of the National Academy of Sciences.

In individuals affected by SMA, the survival motor neuron - 1 (SMN1) gene is mutated and lacks the ability to process a key protein that helps neurons function.

Studies involving mice also helped to answer a key question: What turns on the activity of the per and tim genes in the first place?

«The key point here is that we can say something about how the gene acts to influence this behavior — that is, is by functioning as a chemical messenger in cells that control this behavior in the brain.

«Essentially, we are using the human placenta as a model to identify genes that play a key role in invasion in both the placenta and cancer,» wrote Chi Sutherland, a Ph.D. candidate leading the project, in an email.

This image shows the metabolic expression of a gene identified by scientists from EPFL in Lausanne and ETH Zürich as being a key player in the development of type 2 diabetes.

Biologists now know that the genome sequence holds only a small part of the answer, and that key elements of development and disease are controlled by the epigenome — a set of chemical modifications, not encoded in DNA, that orchestrate how and when genes are expressed.

The key insight for building such drugs came to Tim Tully, founder and chief science officer of Helicon, when his team at Cold Spring Harbor Laboratory on Long Island stumbled upon the molecular switch: a gene called CREB, which is involved in converting short - term memories into long - term ones.

While most of biology and medicine focus on the key roles genes and chemicals play in the formation and control of living systems, the spatial arrangement of the components that make up those systems and the physical forces they experience are being increasingly recognized as equally important.

But a new study, published today in Nature, has revealed that m6A plays a key role in the regulation of the Sex - lethal (Sxl) gene, which controls sex determination of the fruit fly Drosophila.

A team of researchers at the Stanford University School of Medicine has used a gene - editing tool known as CRISPR to repair the gene that causes sickle cell disease in human stem cells, which they say is a key step toward developing a gene therapy for the disorder.

Changes in key genes clearly define four previously unknown conditions within the umbrella diagnosis of schizophrenia, according to a study led by researchers from NYU Langone Medical Center published online April 28 in EBioMedicine, a Lancet journal.

For the first time, the response of more than 10,000 genes was followed simultaneously, which identified brassinosteroids and auxins and their signalling molecules as key to the growth stimulation observed in biochar.

«When most people think about cancer genetics, they think about single key mutations that foster tumor formation — very specific things like the BRCA genes,» said Joe R. Delaney, PhD, a fellow in the Clinical Translation program at UC San Diego Moores Cancer Center and lead author of the paper published February 15 in Nature Communications.

In individuals affected by SMA, the spinal motor neuron - 1 (SMN1) gene is mutated and lacks the ability to process a key protein that helps muscle neurons function.

The gene amplifies transmission of electrical signals — a key step in strengthening connections.

Research published this month in Nature Neuroscience identified a surprisingly small set of molecular patterns that dominate gene expression in the human brain and appear to be common to all individuals, providing key insights into the core of the genetic code that makes our brains distinctly human.

Readers will have at their fingertips key articles in the history of science from the late 19th through the early 21st centuries, including research about the human genome, breast and colon cancer genes, and the Bose - Einstein condensate in physics.

Indeed, the group found that the affected gene, named left - right dynein (lrd), comes on in the «node» — a key source of patterning signals — just before the appearance in the mouse embryo of the first known left - right asymmetries, the left - sided expression of two genes called nodal and lefty.

It was assumed that these fish became blind because mutations disabled key genes involved in eye development.

The second gene, TNFRSF6B, encodes a receptor related to those that bind tumor necrosis factor (TNF)-- a key chemical signal for triggering inflammation in IBD as well as in patients with other autoimmune disorders such as rheumatoid arthritis and psoriasis.

Of the nearly 7,000 genes in the mycobacterial genome, one region spanning just 6 genes appears to be key in determining whether a mycobacterial strain will be a donor or recipient when it comes to mating.

What's more, they managed to disable the gene in 65 per cent of cells in the key area of the animals» brains.