Not exact matches
The Company focuses on discovering and developing small
molecule drugs directed against tumor and
immune cell targets that control
key metabolic pathways in the tumor microenvironment.
One
key gene encodes the making of a receptor called TREM2, a docking site for
molecules on the surface of microglia and other innate
immune cells.
Because Zika typically has trouble establishing infections in mice, the researchers used animals that were genetically altered so that they could not produce interferon, a
key immune system signaling
molecule, thus dampening the animals»
immune response to the virus.
The study pinpoints an
immune molecule called interferon gamma as the
key to this link.
Jules Hoffmann of the University of Strasbourg in France first identified a
key molecule, called Toll, involved in the innate
immune response in fruit flies.
But by eliminating the sugar
molecule, the new mutation also affects «a
key region in the virus that is targeted by the
immune system,» Hensley adds, making the vaccine less effective.
The HLA (human leukocyte antigen) is a system of genes responsible for regulating
immune responses, and peptides are short chains of amino acids that play
key roles in regulating the activities of other
molecules.
Since T cells can only recognize neoantigens that are «presented» to them by HLA
molecules of the
immune system, a
key step in making the vaccine is using computer algorithms to predict which neoantigen peptides will bind strongly to the HLA
molecules for recognition by T cells.
Many of the
key molecules and proteins that allow our
immune system to work have been visualised in unprecedented detail with this technology.
A team of researchers based partly in South Africa has identified a
key set of
immune system
molecules that helps determine how effectively a person resists infection with human immunodeficiency...
Antibodies are
key effector
molecules in health and disease as they harbor the ability to recognize specific molecular structures and, consequently, elicit
immune responses.
Through his work with large patient groups, he has managed to show that narcolepsy is closely genetically linked to so - called HLA
molecules, which play a
key part in the
immune system by presenting foreign substances to
immune cells.
And,
key regulatory hormones, such as insulin, are also proteins, as are many important
molecules in our
immune system and cell transport and messaging
molecules.
The
immune system creates two
key molecules: interleukin and interferon.
What is known is that the
immune system creates two
key anti-cancer
molecules called: interleukin and interferon.
The
immune system creates two
key molecules called: interleukin and interferon.