Sentences with phrase «key mechanisms in»

Scientists from the Academy of Immunology and Microbiology (AIM) within IBS in South Korea have recently uncovered one of the key mechanisms in the small intestine that triggers this process.

Researchers at the University of Leeds have made a new synthetic anti-cancer molecule that targets two key mechanisms in the spread of malignant tumors through the body.

«In this research we determined that in cases of severe infection and sepsis, a key mechanism in the body's response to infection is broken.

«Key mechanism in the plant defense against fungal infections.»

The treatment did a lot to prevent cell migration, a key mechanism in metastasis, in experiments on laboratory cultures (in vitro) of cancerous human cells.

«Accretion of cool molecular gas is thought to be a key mechanism in galaxy evolution.

Another key mechanism in their strategy involves variable spending rules that link «spending» (income generated by the portfolio) to the performance of the portfolio.

This study identified a key mechanism in chemotherapy resistance in hemangiosarcoma tumors.

Interpersonal family stress contributes to relationship breakdown and lack of perceived social support, and high expressed emotion may contribute to relapse.21 Family - focused treatment has been shown to reduce recurrence when used as an adjunct to medication for bipolar disorder.38 It is initiated once stabilisation of mood has been effected after an acute episode, and includes the patient and at least one significant family member (eg, parent or spouse).39 The underlying focus of family - focused treatment is to provide education regarding the recent illness episode; this includes exploring possible causes and the patient's personal triggers, discussing the importance of medication, differentiating between the person and the illness, and enhancing positive family relationships.40 Improved positive communication appears to be a key mechanism in this approach.38, 41 Recent studies suggest greater benefits in reducing depressive rather than manic relapses.23, 38,42

There is also increasing empirical support for the premise that change in parental behaviour is a key mechanism in producing child behaviour change.

Not exact matches

As Stanek explained, «The key to dynamic HTML in both Internet Explorer and Navigator is a live update mechanism that allows a browser to modify sections of a Web page in the background.

M&A will never be 100 % successful and we learn from every deal we do, and so not to pick on any specific deal, but I've learned, based on relative success of deals we've done in the past, is making sure the key leaders at the company share a vision with the founder, making sure the strategy drives the M&A, as opposed to the M&A driving the strategy, and making sure we have good support mechanisms for these companies after they come in.

Though the researcher said there needs to be more research into the exact mechanisms of why that is, they concluded that «healthy sleep appears to play an important role in maintaining brain health with age, and may play a key role in [Alzheimer's disease] prevention.»

Although the digital currency isn't literally in your head, the access mechanism (a 12 - word phrase) to a private key (which opens your Bitcoin wallet) is known only to you.

Messaging platforms like Slack, HipChat, or Skype are key distribution mechanisms for chatbots and already mainstream in the enterprise.

The ONLY key element defined in the original Satoshi whitepaper is the mechanism to resolve the Byzantine Generals problem.

Informal networks play a key role in building a trust mechanism that dispels the fear in rebels to quit...

In 2005, NDRC, another powerful government department overseeing outward investment, and China Export and Credit Insurance Corporation set up a risk prevention mechanism for key overseas investment projects.

While difficult for those with travel or business expenses in U.S. dollars, the lower exchange rate is a key mechanism of adjustment for the Canadian economy.

A recent analysis of the Longitudinal Study of Australian Children (LSAC) found that, in fathers, a higher parenting self - efficacy score was related to lower work - family strain; and a key mechanism by which fathers» work / family strain was decreased was by their doing more than they regarded as their «fair share» of child rearing tasks.

This vital information often is the key to understanding the breast mechanisms and points of intervention that may cause significant delay in milk production and glandular response.

In addition to identifying key stressors and larger sociopolitical mechanisms related to homebirth transfers, they also consider possible solutions in the movement towards developing an integrated maternity systeIn addition to identifying key stressors and larger sociopolitical mechanisms related to homebirth transfers, they also consider possible solutions in the movement towards developing an integrated maternity systein the movement towards developing an integrated maternity system.

Indeed, many consider the development of emotional self - regulation in particular to be one of the key processes in childhood behaviour problems.27, 28,29,30 For example, in characterizing the behaviour of children with early externalizing behaviour problems, there is often reference to a lack of control, under - control, or poor regulation.29, 30 In characterizing the behaviour of children with internalizing disorders, there is often a discussion of over - control.12 Understanding the role of temperament in child development may be facilitated by examining the possible mediational effects of emerging self and emotion regulation, and may provide a more proximal mechanism for the development of different forms of behavioural adjustment difficulties characteristic of childhooin particular to be one of the key processes in childhood behaviour problems.27, 28,29,30 For example, in characterizing the behaviour of children with early externalizing behaviour problems, there is often reference to a lack of control, under - control, or poor regulation.29, 30 In characterizing the behaviour of children with internalizing disorders, there is often a discussion of over - control.12 Understanding the role of temperament in child development may be facilitated by examining the possible mediational effects of emerging self and emotion regulation, and may provide a more proximal mechanism for the development of different forms of behavioural adjustment difficulties characteristic of childhooin childhood behaviour problems.27, 28,29,30 For example, in characterizing the behaviour of children with early externalizing behaviour problems, there is often reference to a lack of control, under - control, or poor regulation.29, 30 In characterizing the behaviour of children with internalizing disorders, there is often a discussion of over - control.12 Understanding the role of temperament in child development may be facilitated by examining the possible mediational effects of emerging self and emotion regulation, and may provide a more proximal mechanism for the development of different forms of behavioural adjustment difficulties characteristic of childhooin characterizing the behaviour of children with early externalizing behaviour problems, there is often reference to a lack of control, under - control, or poor regulation.29, 30 In characterizing the behaviour of children with internalizing disorders, there is often a discussion of over - control.12 Understanding the role of temperament in child development may be facilitated by examining the possible mediational effects of emerging self and emotion regulation, and may provide a more proximal mechanism for the development of different forms of behavioural adjustment difficulties characteristic of childhooIn characterizing the behaviour of children with internalizing disorders, there is often a discussion of over - control.12 Understanding the role of temperament in child development may be facilitated by examining the possible mediational effects of emerging self and emotion regulation, and may provide a more proximal mechanism for the development of different forms of behavioural adjustment difficulties characteristic of childhooin child development may be facilitated by examining the possible mediational effects of emerging self and emotion regulation, and may provide a more proximal mechanism for the development of different forms of behavioural adjustment difficulties characteristic of childhood.

e) Re-commit to open government and open data — in the coming years, transparency will be one of the key mechanisms by which the government can explain what it is doing, and ordinary people can feel they are well informed about the changes to come.

In the case of devolution to UK cities, the key focus seems to be on devolution as a mechanism of economic regeneration?

In a rough outline, the governor touted public - private partnerships (or PPPs, as they're known) as a key mechanism to pay for «the repair and development of highways, bridges and major construction projects.»

«The Government should increase the intake of Schools of Midwifery & Nursing to 100 and the State should devise a mechanism for safer blood transfusion by equipping one comprehensive health centre and one secondary health centre per LGA Other recommendations include, all key institutional stakeholders such as the Ministry of Health, Hospital's Management Board and the Ondo State Primary Healthcare Development Board should be strengthened to better perform their respective regulatory and implementation roles as regards the RBF in the state.

A key factor in eroding the Conservatives» poll lead in the 1992 was Black Wednesday, when the pound's disastrous exit from the European exchange rate mechanism ruined the Tories» reputation for economic competence.

This week will be full of both private negotiations and public sessions in Albany, where lawmakers attempt to come to a budget deal while showing significantly divergent takes on key issues - as well as central mechanisms related to the budget and policy.

The next key event was the Conservative conference in the autumn of 1992, held after the government had been forced to leave the European exchange rate mechanism.

Analysis of endogenous small RNAs indicated that a fraction derive from a biosynthetic mechanism that is similar to that of secondary siRNAs formed during RNAi, suggesting that small antisense transcripts derived from cellular messenger RNAs by RdRP activity may have key roles in cellular regulation.

One of the key questions in cancer biology is to understand the mechanisms that control tumor heterogeneity and to determine to which extend tumor heterogeneity influences clinical outcome.

Clipping the younger flies» wings significantly reduced the positive effects on the mutants» life span, suggesting that physical activity plays a key role in the life - extending mechanism.

«This is wonderfully serendipitous — our drug just happens to be able to overcome both of the biological mechanisms that are key to survival of aggressive lymphoma,» Dr. Melnick says, adding that the inhibitor completely eradicated DLBCL in mice in a short time, with no detectable side effects.

Publishing online this week in Cell Host & Microbe, researchers at Johns Hopkins report the discovery of a key underlying immune mechanism that explains why to how our skin becomes inflamed from conditions such as atopic dermatitis, more commonly known as eczema.

A key breakthrough in the research came when the scientists discovered something that was previously unknown — a molecular mechanism in the Fanconi anemia DNA repair pathway apparently makes T - ALL resistant to chemotherapy.

This could be key given that the underlying mechanisms of metastasis and resistance to cancer drugs are nothing if not complex interactions in a biological system.

In a study published in the journal Science, an international collaboration of investigators from Dana - Farber, Harvard Medical School, Boston Children's Hospital, and the University of Strasbourg uncovered a mechanism that allows key immune system cells to keep a steady rein on their more belligerent brother cells, thereby protecting normal, healthy tissue from assaulIn a study published in the journal Science, an international collaboration of investigators from Dana - Farber, Harvard Medical School, Boston Children's Hospital, and the University of Strasbourg uncovered a mechanism that allows key immune system cells to keep a steady rein on their more belligerent brother cells, thereby protecting normal, healthy tissue from assaulin the journal Science, an international collaboration of investigators from Dana - Farber, Harvard Medical School, Boston Children's Hospital, and the University of Strasbourg uncovered a mechanism that allows key immune system cells to keep a steady rein on their more belligerent brother cells, thereby protecting normal, healthy tissue from assault.

It must also be a key priority at the G7 summit in June 2015... We call for one of their recommendations to be the establishment of a global biomedical R&D fund and mechanism for innovations of public health importance.»

The researchers behind the new study say that the fact that this mechanism is highly similar in human cells and yeast cells suggests that it plays a key role in ensuring proper chromosome distribution following each cell division.

As his research progressed and he and others began unraveling the sophisticated mechanism by which the Ebola virus enters cells, he was «bitten by the Ebola bug» and made studying the virus a key focus of his lab, which he started up in 2007.

Published a month apart in PLOS Pathogens, the studies from Professor Ethan Bier's laboratory used a series of experiments to identify key pathways and mechanisms previously unknown or overlooked in the body's defenses.

Using the nanodiscs, the team elucidated the activation mechanism of receptor kinase AgrC and discovered a key regulatory hotspot in the kinase that could greatly affect its activity.

University of Tokyo researchers have discovered the structure and transport properties of the «intermediate state» in lithium - ion batteries — key to understanding the mechanisms of charge and discharge in rechargeable batteries.

Until now, scientists were unable to prove that mammals use RNAi for killing viruses, but ironically, it was Ding's earlier research into plants, nematodes and fruit flies that helped him find the key: viruses have been outwitting that innate protection in our cells by using proteins to suppress our virus - killing mechanism.

They also are key to cell differentiation in developing organisms, but the mechanisms are not fully understood.

Autophagy has emerged as a key pathway that cancer cells use to survive in the face of assault by chemotherapy and radiation; however, autophagy as a potential druggable mechanism in patients who become resistant to BRAF inhibitors has not been investigated.

A new investigation of more than 48,000 stored tumor samples finds evidence of a key deficiency in a repair mechanism designed to keep DNA from being mutated and causing cancer.

These techniques are key to understanding the molecular mechanisms underlying cell function in healthy and diseased individuals and the development of diseases like cancer.

The key to this device is not so much in its physical mechanisms but in the algorithms behind it, says neurosurgeon Edward Chang of the University of California, San Francisco.