Sentences with phrase «key mechanisms of»

Accordingly, there is considerable evidence that improvements in parenting skills are key mechanisms of change in these interventions, with outcomes accounted for by both increased positive parenting (e.g., warmth, contingent positive reinforcement) and decreased negative parenting (e.g., harsh / inconsistent discipline; Beauchaine et al. 2005; Gardner et al. 2006).

Travel can seriously mess with key mechanisms of oral contraceptives such as The Pill, rendering travellers susceptible to unplanned pregnancy.

Because cyclodextrin treatment in humans is safe (FDA approved application of 2 hydroxypropyl - β - cyclodextrin for the treatment of Niemann - Pick disease, type C. Phase I clinical trial) and cyclodextrin beneficially affects key mechanisms of atherogenesis, it may therefore be used clinically to prevent or treat human atherosclerosis http://stm.sciencemag.org/content/8/333/333ra50.

Borgeson said one of lipoxin A4's key mechanisms of action is to switch the phenotype of the fat tissue macrophage cells from inflammatory to anti-inflammatory.

Some of the common genetic alterations identified in the study were gains and losses in chromosome 8, as well as cell proliferation and cell - cycle progression — key mechanisms of cancer caused by genetic alterations — linked to the genes AURKA, AURKB and FOXM1.

Whereas most traditional antibiotics target specific groups of bacteria and kill by disrupting key mechanisms of those microbes, SAAP - 148 is more of a generalist.

While difficult for those with travel or business expenses in U.S. dollars, the lower exchange rate is a key mechanism of adjustment for the Canadian economy.

«Anandamide, an endocannabinoid, has been shown to have neuroprotective effects against seizures in basic research studies and this may turn out to be a key mechanism of seizure control,» explained Dale Deutsch, PhD, Professor of Biochemistry and Cell Biology and a faculty member of the Institute of Chemical Biology and Drug Discovery at Stony Brook University.

An explanatory research question asks is an increase in mindfulness skills the key mechanism of change?

Not exact matches

As Stanek explained, «The key to dynamic HTML in both Internet Explorer and Navigator is a live update mechanism that allows a browser to modify sections of a Web page in the background.

M&A will never be 100 % successful and we learn from every deal we do, and so not to pick on any specific deal, but I've learned, based on relative success of deals we've done in the past, is making sure the key leaders at the company share a vision with the founder, making sure the strategy drives the M&A, as opposed to the M&A driving the strategy, and making sure we have good support mechanisms for these companies after they come in.

Though the researcher said there needs to be more research into the exact mechanisms of why that is, they concluded that «healthy sleep appears to play an important role in maintaining brain health with age, and may play a key role in [Alzheimer's disease] prevention.»

To government officials and consumer watchdogs alike, it's a sign that a key element of Washington's chief mechanism for overseeing Facebook — and many of its privacy - infringing tech industry peers — isn't sufficiently independent and may lack teeth.

If a non-replay mechanism is properly integrated, spending your BTC will not spend your BTU and both coins and chains will exist individually.If multiple chains stand the test of time, CoolWallet will update our function, adding BTC and BTU switch, so that our users can manage both their BTC and BTU coins at the same time, and without exporting their private keys.

It may be used as a funding mechanism for your buy - sell agreement and as business interruption insurance to pay the business for interruptions caused by the death of key employees.

Some key parts of the agreement are the reduction (or elimination) of tariffs on a wide variety of goods and services, ranging from alcohol to beef and pork, and the creation of an investor - state dispute settlement mechanism.

9 Therefore globalization as a concept and a working mechanism translates the compulsive logic and propellants of capitalist accumulation and dis - accumulation which could provide a key to the working and failure of the system.

The future of research into the potential health benefits of cocoa should focus on the mechanisms and active compounds, with well defined clinical trials key to this burgeoning segment, says a new review by Nestlé.

It is the key mechanism to «bridge the gap» to the sustainable diversion limits (the recovery of 2,750 GLs) under the Murray Darling Basin Plan.

A recent analysis of the Longitudinal Study of Australian Children (LSAC) found that, in fathers, a higher parenting self - efficacy score was related to lower work - family strain; and a key mechanism by which fathers» work / family strain was decreased was by their doing more than they regarded as their «fair share» of child rearing tasks.

This vital information often is the key to understanding the breast mechanisms and points of intervention that may cause significant delay in milk production and glandular response.

The key difference between a Diaper Genie and your run - of - the - mill kitchen can is a clever little mechanism that ensures that the main storage compartment remains closed at all times, even when the lid is open.

Other key features of this stroller include its double wheel system for a smoother ride, an adjustable 5 - point harness, and a one hand folding mechanism.

Indeed, many consider the development of emotional self - regulation in particular to be one of the key processes in childhood behaviour problems.27, 28,29,30 For example, in characterizing the behaviour of children with early externalizing behaviour problems, there is often reference to a lack of control, under - control, or poor regulation.29, 30 In characterizing the behaviour of children with internalizing disorders, there is often a discussion of over - control.12 Understanding the role of temperament in child development may be facilitated by examining the possible mediational effects of emerging self and emotion regulation, and may provide a more proximal mechanism for the development of different forms of behavioural adjustment difficulties characteristic of childhood.

e) Re-commit to open government and open data — in the coming years, transparency will be one of the key mechanisms by which the government can explain what it is doing, and ordinary people can feel they are well informed about the changes to come.

In the case of devolution to UK cities, the key focus seems to be on devolution as a mechanism of economic regeneration?

Conversely, disrupting the mechanisms of party strategy, such as the message of the day and surrogate talking points, will provide key enabling capabilities for some future, truly democratic, Democratic Party.

In a rough outline, the governor touted public - private partnerships (or PPPs, as they're known) as a key mechanism to pay for «the repair and development of highways, bridges and major construction projects.»

«The Government should increase the intake of Schools of Midwifery & Nursing to 100 and the State should devise a mechanism for safer blood transfusion by equipping one comprehensive health centre and one secondary health centre per LGA Other recommendations include, all key institutional stakeholders such as the Ministry of Health, Hospital's Management Board and the Ondo State Primary Healthcare Development Board should be strengthened to better perform their respective regulatory and implementation roles as regards the RBF in the state.

This week will be full of both private negotiations and public sessions in Albany, where lawmakers attempt to come to a budget deal while showing significantly divergent takes on key issues - as well as central mechanisms related to the budget and policy.

The next key event was the Conservative conference in the autumn of 1992, held after the government had been forced to leave the European exchange rate mechanism.

This report is intended to foster understanding of those mechanisms among the science and engineering community and provide a record of key debates.

«Understanding the molecular mechanism of the disease is the key to finding a treatment that works.»

Analysis of endogenous small RNAs indicated that a fraction derive from a biosynthetic mechanism that is similar to that of secondary siRNAs formed during RNAi, suggesting that small antisense transcripts derived from cellular messenger RNAs by RdRP activity may have key roles in cellular regulation.

One of the key questions in cancer biology is to understand the mechanisms that control tumor heterogeneity and to determine to which extend tumor heterogeneity influences clinical outcome.

«This is wonderfully serendipitous — our drug just happens to be able to overcome both of the biological mechanisms that are key to survival of aggressive lymphoma,» Dr. Melnick says, adding that the inhibitor completely eradicated DLBCL in mice in a short time, with no detectable side effects.

Publishing online this week in Cell Host & Microbe, researchers at Johns Hopkins report the discovery of a key underlying immune mechanism that explains why to how our skin becomes inflamed from conditions such as atopic dermatitis, more commonly known as eczema.

This could be key given that the underlying mechanisms of metastasis and resistance to cancer drugs are nothing if not complex interactions in a biological system.

In a study published in the journal Science, an international collaboration of investigators from Dana - Farber, Harvard Medical School, Boston Children's Hospital, and the University of Strasbourg uncovered a mechanism that allows key immune system cells to keep a steady rein on their more belligerent brother cells, thereby protecting normal, healthy tissue from assault.

Researchers at the University of Leeds have made a new synthetic anti-cancer molecule that targets two key mechanisms in the spread of malignant tumors through the body.

It must also be a key priority at the G7 summit in June 2015... We call for one of their recommendations to be the establishment of a global biomedical R&D fund and mechanism for innovations of public health importance.»

It has been used to make a bewildering variety of objects, from toothed gears to 3D boxes with a lock - and - key mechanism.

As his research progressed and he and others began unraveling the sophisticated mechanism by which the Ebola virus enters cells, he was «bitten by the Ebola bug» and made studying the virus a key focus of his lab, which he started up in 2007.

«Our work introduces a design scheme to mimic the key flight mechanisms of biological bats,» said Chung, who is also a research scientist at the Jet Propulsion Laboratory, which Caltech manages for NASA.

Next, Lu et al. found that 3BNC117 was not effective at clearing infected cells when their Fcγ receptor was mutated or blocked, suggesting that this receptor is a key mechanism behind 3BNC117 - mediated clearance of HIV - infected cells.

Published a month apart in PLOS Pathogens, the studies from Professor Ethan Bier's laboratory used a series of experiments to identify key pathways and mechanisms previously unknown or overlooked in the body's defenses.

Using the nanodiscs, the team elucidated the activation mechanism of receptor kinase AgrC and discovered a key regulatory hotspot in the kinase that could greatly affect its activity.

University of Tokyo researchers have discovered the structure and transport properties of the «intermediate state» in lithium - ion batteries — key to understanding the mechanisms of charge and discharge in rechargeable batteries.

Autophagy has emerged as a key pathway that cancer cells use to survive in the face of assault by chemotherapy and radiation; however, autophagy as a potential druggable mechanism in patients who become resistant to BRAF inhibitors has not been investigated.

A new investigation of more than 48,000 stored tumor samples finds evidence of a key deficiency in a repair mechanism designed to keep DNA from being mutated and causing cancer.