Sentences with phrase «key mouse tests»

Not exact matches

It is these long lasting memories and drug - associated cues, key to the transition from recreational drug taking to compulsive drug use, which the new treatment inhibited when tested on mice.

When the researchers used optogenetics, a biological technique which involves the use of light to control neurons, to inhibit the key social - spatial pathway they had identified in the brain, the test mouse wandered freely through the space.

Chung and his team used mice to test the potentially key role this enzyme plays in obesity and exercise capacity.

Although the behavior of the mutant mice seemed mostly normal, further testing showed that they had deficiencies in spatial learning, confirming the enzyme's key role in that process.

This call for projects «Mouse models and rare diseases» aims to give a significant boost to the development of mouse models, in order to: ◊ gain a better understanding of the pathophysiological mechanisms involved in rare diseases whose defective genes have been identified ◊ test and validate therapeutic proofs of concept, at the pre-clinical in vivo level Indeed, producing these models meets a key objective in the development of a therapeutic straMouse models and rare diseases» aims to give a significant boost to the development of mouse models, in order to: ◊ gain a better understanding of the pathophysiological mechanisms involved in rare diseases whose defective genes have been identified ◊ test and validate therapeutic proofs of concept, at the pre-clinical in vivo level Indeed, producing these models meets a key objective in the development of a therapeutic stramouse models, in order to: ◊ gain a better understanding of the pathophysiological mechanisms involved in rare diseases whose defective genes have been identified ◊ test and validate therapeutic proofs of concept, at the pre-clinical in vivo level Indeed, producing these models meets a key objective in the development of a therapeutic strategy.

Specific Aim 2: Having utilized mutant mice to identify the key players in AMD pathology from Specific Aim 1, we will develop and test molecules that target either the anaphylatoxins or the MAC, or both, in the context of practical therapies that can be utilized in humans.

The key was the development of a special «birdcage» coil for MRI of the mouse mammary glands, and the team began testing a wide range of protocols to get images that could distinguish between cancer, normal breast tissue and fat.

Having discovered a genetic «key» (called P - TEFb) that is important in both cancer cell growth and immune cell differentiation, they tested the drugs on a mouse model for uveitis, an incurable eye condition in which the immune system mistakenly attacks healthy tissue leading to inflammation of the uvea (the middle layer of the eye).

After the vocabulary has been introduced and key teaching points explained, further slides test the children's vocabulary before the answer appears on the click of the mouse.