Sentences with phrase «key protein domains»

Another algorithm, PolyPhen, applies protein structural information in a rule - based system to evaluate whether a mutation affects key protein domains.

It has three key protein domains: a DNA - binding domain, a chromodomain (which may bind euchromatin), and a helicase domain (which is thought to activate transcription by acting against repressing transcription effects, such as heterochromatin structure).

Not exact matches

A protein domain once considered of little importance may be key to helping patients who are fighting acute myeloid leukemia (AML) avoid a relapse.

He discovered that one of the vesicle membrane proteins, synaptotagmin, had separate calcium and phospholipid binding domains, suggesting it had a key role in transmitter release.