Sentences with phrase «key proteins involved»

Since 2007 he has focussed his research on kinase structural biology and structures of key proteins involved in cell signalling.

Robin Dowell, Ph.D., CU - Boulder: Understand how an extra copy of chromosome 21 affects the behavior of key proteins involved in regulating expression

The two teams (Südhof also partly in collaboration with Reinhard Jahn) purified, cloned and defined the functions of virtually all the key proteins involved in neurotransmitter release.

Key proteins involved in gene expression depend on each other when forming a heart in an embryo, but, if left alone, they start to run amok

This is why recent work in the field of cancer research has focused on picking apart the complex cellular pathways involved in the development of different cancers and identifying the roles of key proteins involved, with the goal of being able to discriminately and effectively eliminate cancerous cells from the body.

Cold Spring Harbor, N.Y. — Human Argonautes (hAgo), are key proteins involved in a process known as RNA interference.

Focusing on just these protein - producing genes allows scientists to zero in on mutations that alter key proteins involved in cancer growth.

Although researchers had identified the key proteins involved, that is, middle T antigen for polyomavirus and Src for Rous, they weren't sure what those proteins did.

They realized that during SCNT, monkey cells lose two key proteins involved in cell and chromosomal division [source: Graham].

They show that the timing of synthesis of a steroid hormone called ecdysone is sensitive to nutrition in the fruit fly and describe the key proteins involved in this regulatory mechanism.

The effort to identify new ways of fighting infections has taken a step forward now that scientists have identified a key protein involved in the host's response to strep infections.

A key protein involved in initiating Alzheimer's disease is called amyloid - beta (Aβ).

BRCA1 is a key protein involved in DNA repair, and mutations that impair its function increase the risk for breast and ovarian cancer.

For 2016, the focus will be on «Dissecting the molecular basis of aluminum tolerance in rice» and the intern will help characterize a key protein involved in rice aluminum tolerance using a variety of molecular tools and strategies.

Not exact matches

A third group first got an injection of a compound known to block the effects of interleukin - 1 beta (IL - 1), a protein involved in activating the inflammatory immune response and shown in previous research to be a key player in modulating fetal brain injury following exposure to inflammation in the womb.

Óscar Llorca and his team have used this technique to learn about the structure and functioning of a complex system called R2TP, which is involved in various key processes for cell survival such as the activation of the kinases mTOR, ATR and ATM, proteins that are the target of various cancer drugs currently being developed.

A key insight from this work has been that short - term memory (lasting minutes) involves chemical modifications that strengthen existing connections, called synapses, between neurons, whereas long - term memory (lasting days or weeks) requires protein synthesis and probably the construction of new synapses.

According to Beg, NF - κB proteins regulate key genes involved in immune response, inflammation, cell death and cell growth.

The method has allowed researchers to study key players involved in cell division — which include proteins that form much of the structure of chromosomes, and fragments of DNA that help to orchestrate the process.

Scientists have captured atomic level snapshots showing how one key enzyme modifies a protein involved in turning genes on or off inside cells.

«Since conventional methods, such as X-ray crystallography, capture only averaged frozen structures, it is not possible to investigate how the dynamic of the protein could be involved in key aspects of their function,» explains physicist Alipasha Vaziri, a joint group leader at the Max F. Perutz Laboratories (MFPL) and the Institute of Molecular Pathology (IMP) and head of the research platform «Quantum Phenomena & Nanoscale Biological Systems» (QuNaBioS) of the University of Vienna.

A new study just published in the journal Glia and available online on July 11th, details the newly discovered mechanism by which astrocytes are involved in inhibitory synapse formation and presents strong evidence that Transforming Growth Factor Beta 1 (TGF β1), a protein produced by many cell types (including astrocytes) is a key player in this process.

To narrow down the number of chemical compounds that could be potential drug candidates, scientists utilize computer models that can predict how a particular chemical compound might interact with a biological target of interest — for example, a key protein that might be involved with a disease process.

A key protein called PRDM16 appears to be involved in the transformation.

Researchers at the Okinawa Institute of Science and Technology Graduate University (OIST) have found that the protein hinders a key step involved in the transmission of neuronal signals, which is essential for higher - brain functioning: vesicle endocytosis at the nerve terminal.

NIH scientists have discovered a mechanism involved in stabilizing key HIV proteins and thereby concealing sites where some of the most powerful HIV neutralizing antibodies bind, findings with potential implications for HIV vaccine research.

This resulted in over 5,000 virus - host protein - to - protein interactions, which the investigators narrowed down to 139 key connections that are necessary for HCV infection, involving all 10 HCV proteins and 133 proteins in the host liver cells.

Research in the lab of Edward P. Feener, Ph.D., Investigator in the Section on Vascular Cell Biology and Director of the Proteomics Core at Joslin Diabetes Center and an Associate Professor of Medicine at Harvard Medical School, now has shown that a substantial percentage of patients with DME do not have high levels of VEGF in the fluid inside their eyes but do have high levels of a protein called PKal (plasma kallikrein) and associated molecules that are key players in an inflammatory molecular pathway involved in the disease.

You'll find out what DNA code represents, how it creates proteins inside the body, and what key molecules are involved.

Although some of the key molecular components involved in the formation of cellular structures and tissue formation are known, we currently lack a bottoms up understanding of how the behavior of these molecules gives rise to the formation of large structures, partly because of the lack of tools for both studying the spatial regulation of soluble proteins and biophysically characterizing the behavior of large structures and tissues.

Richard Scheller has used a combination of biochemistry, molecular biology, and cell biology to identify several key synaptic vesicle and plasma membrane proteins involved in fusion of the neurotransmitter - containing vesicles with the membrane of the presynaptic terminal.

«We identified additional key components to PSII involved in assembly and function,» said Dr. Jon Jacobs, a protein chemist at PNNL.

In the late 1990s, he and Reinhard Jahn, now at the Max Planck Institute of Biophysical Chemistry, determined the structures of some of the key proteins and complexes involved in the process of synaptic vesicle fusion.

9/20/2007 UCSD Study Reveals the Regulatory Mechanism of Key Enzyme Protein kinase A (PKA) involved in cardiac disease and breast cancer Research conducted at the University of California, San Diego (UCSD) School of Medicine has shed new light on the structure and function of one of the key proteins in all mammalia... MoreKey Enzyme Protein kinase A (PKA) involved in cardiac disease and breast cancer Research conducted at the University of California, San Diego (UCSD) School of Medicine has shed new light on the structure and function of one of the key proteins in all mammalia... Morekey proteins in all mammalia... More...

PTPN22 is involved in the formation of a key protein known as lymphoid tyrosine phosphatase (LYP), which helps control the activity of T and B cells in the immune system.

Black arrows show the brain region responsible for producing seizures in a patient involved in a new study showing that loss of the protein CLOCK may be a key factor in severe forms of focal epilepsy.

By targeting the protein made by a major disease gene, we are in a position to manipulate the key biological pathway involved in the disease.

To address key questions of meiotic ploidy reduction, we screen for and characterise novel meiotic proteins, focusing on proteins that are specifically involved in meiotic chromosome segregation and chromosome dynamics in mice.

Our researchers have made key discoveries of the specific gene mutations and proteins involved in both syndromic and non-syndromic congenital sideroblastic anemias, and we have an open research protocol that is helping us to reach our ultimate goal of understanding the genetic basis of all types of CSAs.

Earlier lab work by the researchers helped explain key mechanisms involved with assisting vitamin D3 to clear the abnormal protein amyloid - beta, which is found within the plaque.

The bracketing method simply involves consuming a high carbohydrate drink typically with a serving of creatine, and sometimes with protein, glutamine, BCAA's or a few other key supplements.

In particular, consuming sunflower seeds more than five times per week was associated with reduced levels of C - reactive protein (CRP), a key chemical involved in inflammation.

A lot of beginning lifters will mistakenly think that since protein is the primary nutrient involved in building muscle, eating more and more protein throughout the day is the key to packing on size as fast as possible.

Energy supply: - Vitamin B1 is vital for releasing energy from starchy foods - Vitamin B2, B6 and niacin help release energy from proteins and fat - Vitamin B12 and folic acid are involved in the formation of red blood cells and therefore key to high performance