Sentences with phrase «key receptor»

It bore a chemical «bump» that the team suspected kept it from locking into key receptors on the surface of immune cells.
The team, led by Thirumala - Devi Kanneganti, Ph.D., a member of the St. Jude Department of Immunology, found key receptors responsible for sensing DNA in cells infected by the tularemia - causing bacterium, Francisella.
It's especially problematic for children with behavioral disorders because it can bind to key receptors that effect mood and behavior, as well as those with autoimmune diseases.
Scientists funded by the National Institutes of Health have achieved a landmark of psychiatric neuropharmacology: deciphering the molecular structure of a widely prescribed antipsychotic docked in its key receptor.
β - arrestin, which has several known roles in signaling systems, also links a key receptor to a motor protein so that the receptor can be transported to cilia for sensing environmental cues.
«The space in lock - and - key receptors is much smaller.»
Using a tool that mimics the cellular environment, Princeton University researchers reconstituted a key receptor protein responsible for regulating S. aureus virulence.
He examined the mice's brains and found that the cells had lower levels of delta GABA, a key receptor subunit that stops nerves from firing too often and has been linked to epileptic seizures.
«Because it targets a key receptor and works through different mechanisms than other available agents, it clearly has merited comprehensive testing in larger clinical trials.
Researchers from North Carolina State University and the National Institutes of Health (NIH) have developed a method that stops allergic reactions by removing a key receptor from mast cells and basophils.
The work, led by Dr Jurriaan Ton and Dr Estrella Luna at the University of Sheffield, has identified the key receptor binding a chemical called BABA (β - aminobutyric acid) which is boosting plant immunity.
For Alzheimer's disease, the aim is for the investigational drug to target major pathologies of the disease and selectively activate a key receptor in the brain.
In the present study, the scientists created a genetically mutant mouse model deficient in type 1A BMP - receptor (BMPR1A), a key receptor for BMP - 7 which has been shown to be associated with obesity in human populations.
GluN2B is part of the N - methyl - D - aspartate receptor, or NMDAR, a key receptor involved in synaptic plasticity.
Cruciferous vegetables are considered to be a good source of antioxidants and may be able to activate a key receptor on our intestinal immune cells that helps fight pathogens and toxins.
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