Sentences with phrase «key regulator»
A "key regulator" refers to a person or entity that has significant control or authority over a particular system, process, or industry. They are responsible for setting rules, overseeing operations, and ensuring compliance. Their influence and decisions can have a major impact on how things work. Full definition
In this post you will learn how you can benefit from understanding just two key metabolic hormones that are also key regulators of fat and sugar storage.
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As they generated this catalogue of genes, they were searching for key regulators of genes for hair cells.
The Eischen group focused on the role of long non-coding RNAs (lncRNAs), which have emerged as key regulators of genes.
[71] Furthermore, EPA and DHA inhibit key regulators of the inflammatory process and suppress their activation which can help alleviate pain and reduce inflamed joints associated with many skeletal disorders.
One mechanism is protein synthesis by key regulators such as S6 kinase (S6K).
Even getting smaller fixes through the agencies may be problematic until the administration gets its own appointees at key regulators such as the Federal Reserve, the Federal Deposit Insurance Corp. and the CFPB.
The expression changes in proneural glioblastoma associated with key regulators in the regression model are consistent with in vivo expression changes in mouse PDGF ‐ driven tumors.
In addition, the lab's research into putative involvement of inflammation pathways in neurodegeneration and other conditions such as autism includes studies focusing on the interaction between the immune system and the brain, with the goal of identifying key regulators of neuroinflammation.
The report reminds that many key regulators, including German Bundesbank, Bank of China, Bank of England, US Federal Reserve, have already launched such initiatives on a local level.
«It appears that UPB1 is a pretty key regulator of this process,» Benfey says.
Professor Taylor added: «This is a counter-intuitive finding but strongly suggests that stomatal pore numbers increase, since we have identified several key regulators of stomatal number that are sensitive to future high CO2.
This information would be crucial for furthering our knowledge concerning key regulators of cellular plasticity.»
«New key regulator of acquisition of immune tolerance to tumor cells in cancer patients.»
«Pin1 is a common key regulator in many types of cancer, and as a result, can control over 50 oncogenes and tumor suppressors, many of which are known to also control cancer stem cells.»
She has characterized key regulators of a signaling pathway that tells cells to grow, a process that goes awry in cancer and diabetes.
Yvonne Gloor (Walch - Solimena, MPG)-- «The Arf GTPase exchange factor sec7p interaction network: unraveling the crosstalk between key regulators of golgi transport» (2007)
Overall, Chd1 definitely merits further investigation as a possible key regulator of stem cell potency and differentiation.
Several IFN signaling pathway — related key regulators, including STAT1, STAT2, IRF - 1, and IRF - 9, were transfected individually or in combination into STAT1 - deficient U3A cells, together with a luciferase reporter gene containing RIG - G promoter.
«Our study focused on a class of enzymes called methyltransferases, which have emerged as key regulators of HIV latency,» explained Melanie Ott, MD, PhD, a senior investigator at Gladstone and lead author of the study published in the scientific journal Cell Host & Microbe.
«Key regulator in pacemakers of our brain, heart discovered.»
As Kia has gained market share, and surpassed the sales volume of major competitors, Nguyen has advocated for greater industry involvement by her company and for the development of more effective relationships and communication with key regulators.
In particular, they are key regulators of energy and glucose.
The role of PI (3,4) P2 is still becoming clear but it may be able to alter the activity of the AKT protein, a key regulator of cell growth.
«Scientists discover peptide that could reduce the incidence of RSV - related asthma: A peptide developed to inhibit a key regulator of asthma responses reduces development of inflammation and «twitchy» airways in mice.»
Akt, a key regulator of cell biology, is directly involved in cell proliferation, cell survival and cell growth.
The missing link turns out to be a protein called sirtuin 1 or SIRT1, which is also a key regulator of aging.
Partly related to its function as a regulator of the immune response, the NF - kB pathway is also a key regulator of cancer progression.
But in addition to these factors, Hunt, who won a share of the 2001 Nobel Prize in physiology or medicine (along with Leland Hartwell and Paul Nurse) for his discovery of cyclin, a key regulator of the cell cycle, emphasizes early independence and playfulness.
This led me to enter the field of developmental and cell biology, and to eventually discover cyclin as a key regulator of the cell cycle.
The key regulator they identified were the RFX transcription factors.
«These subcortical circuits are the key regulators of our emotional life,» said Helen Mayberg, a professor of psychiatry, neurology and radiology at Emory University who was not involved in this research.
The team has identified the protein kinase MSK1 as a key regulator of dormant or latent metastases.
According to the authors, this is the first study to identify this protein as a key regulator in cellular senescence, a process in which cells stop multiplying.
In the intestinal stem cell niche, the key regulators are hormones called R - spondins and Wnts, which are frequently expressed together.
The researchers found that mutations to a gene called ATF6, a key regulator of the unfolded protein response, can lead to achromatopsia, a hereditary visual disorder characterized by color blindness, decreased vision, light sensitivity, and uncontrolled eye movement in children.
The new findings come on the heels of a series of pivotal discoveries made by Yuan and colleagues over the last decade revealing RIPK1 as a key regulator of inflammation and cell death.
«In this study, we show that PVT1 can be a key regulator of MYC protein, which can shift the paradigm in our understanding of MYC amplified cancers.»
And when researchers experimentally increased deltaFosB levels in normal mice, calbindin expression was suppressed and the animals» memory deteriorated, demonstrating that deltaFosB and calbindin are key regulators of memory.
Researchers from the Vetmeduni Vienna have now discovered that NK cells can switch and promote tumor growth, with STAT5 acting as the key regulator.
Using newly discovered information, the researchers made significant advances in developing a family of drug candidates that target a receptor known as peroxisome proliferator - activated receptors gamma (PPARγ), a key regulator of stem cells controlling bone formation and bone resorption and a master regulator of fat.
The key regulator of autophagy is the protein Atg1.
They also found that a protein called Seven in absentia 2 (Siah2) is a key regulator of the turnover of a well - studied, clock nuclear protein called RevErbα on a 24 - hour cycle.
To start the process, both the key regulator Atg1 as well as the «waste» to be discarded are separately brought to the precise location where the waste is packed into cellular «garbage bags.»
Their results, the researchers conclude, identify IL - 28B as a key regulator of the immune response to influenza vaccination.