Sentences with phrase «key role in cancer»
In this new model, we propose that this loss may play a key role in cancer by disrupting the communication between cells that is essential to healthy cell turnover, allowing more aggressive cancer cells to take over.»
https://articles.mercola.com/
She chose the dynamics and function of the tumor suppressor protein p53, which plays a key role in cancer and is widely studied.
Using the same computer - based approach, the team has now been able to target the c - FLIP (cellular FLICE [FADD - like IL - 1β - converting enzyme]- inhibitory) protein, known to play a key role in cancer stem cell maintenance and survival, described in previously published work by the Institute.
Not exact matches
That's the Manhattan law firm perhaps best known (in political circles, anyway) for its key role in the corruption scandal of now former Assembly Speaker Sheldon Silver, and in legal circles for representing clients suffering from mesothelioma, an asbestos - related cancer.
«The insurance industry has a key role to play in helping to ensure that access to the very best healthcare and drugs becomes a realistic choice for most people, not just the very few who can afford to pay for cancer drugs that can cost many tens of thousands of pounds.»
«Cancer Research UK scientists first discovered abiraterone and subsequently played a key role in its development, including funding the first clinical trials.
«Essentially, we are using the human placenta as a model to identify genes that play a key role in invasion in both the placenta and cancer,» wrote Chi Sutherland, a Ph.D. candidate leading the project, in an email.
For prostate cancer, the key reason for the fall in death rates is improved management and treatment, with a possible role played by screening and early diagnosis.
But a new study suggests that mature cells also play a key role in initiating cancer — a finding that could upend the way scientists think about the origins of the disease.
They looked beyond lung cancer, and discovered the KRAS - variant played a key role in half a dozen other particularly lethal malignancies, especially in women.
Working with human breast cancer cells and mouse models of breast cancer, scientists identified a new protein that plays a key role in reprogramming cancer cells to migrate and invade other organs.
«Mysterious» non-protein-coding RNAs play important roles in gene expression: Study describes how enhancer RNAs are key to gene expression, possibly cancer mutations.»
The work, funded by national charity Pancreatic Cancer Research Fund, uncovers new evidence that PAK4 plays a key role in enabling cancer cells to grow and to spread from the pancreas into other areas of the body, a process called metasCancer Research Fund, uncovers new evidence that PAK4 plays a key role in enabling cancer cells to grow and to spread from the pancreas into other areas of the body, a process called metascancer cells to grow and to spread from the pancreas into other areas of the body, a process called metastasis.
The researchers also confirmed the key role of a peptide (an extremely small protein) in regulating vascular access of the nanoparticle to the cancer site.
He says that the extracts from their fibroblasts do contain the sticky substance, but that in spalacids it does not seem to play a key role in the animals» natural resistance to cancer or activity against cancer cells in the lab.
Scientists from the Crick Institute, London and the Hebrew University, Jerusalem, discover a protein that plays a key role in turning cancer tumor cells into cancer stem cells that are able to renew outbreaks of the disease
The adhesive properties of cancer cells play a key role in the formation and development of a tumour.
Both papers analyzed members of the RAF gene family that play key roles in driving cancer.
It's helped Bertozzi capture the first images of glycoproteins, proteins coated with sugars that play a key role in diseases such as cancer.
Most excitingly, by comparing between individual cells, the team expect to reveal differences which could play key roles in both the early stages of life and the first stages of diseases such as cancer.
«Liver cancer is a deadly disease,» says Luca Tordella, a postdoctoral researcher at the CSC who played a key role in the study.
The work suggests that these viral fossils probably played a key role in the evolution of our species, adds Harmit Malik, an evolutionary biologist at the Fred Hutchinson Cancer Research Center in Seattle, Washington.
Due to these crucial roles in regulating normal cellular behavior, redox status has been recognized as a key area of biological research in various diseases, including cancer.
In a study published in Proceedings of the National Academy of Sciences, researchers at Tokyo Medical and Dental University (TMDU) report the discovery of an RNA molecule that may play a key role in bone restructuring caused by prostate canceIn a study published in Proceedings of the National Academy of Sciences, researchers at Tokyo Medical and Dental University (TMDU) report the discovery of an RNA molecule that may play a key role in bone restructuring caused by prostate cancein Proceedings of the National Academy of Sciences, researchers at Tokyo Medical and Dental University (TMDU) report the discovery of an RNA molecule that may play a key role in bone restructuring caused by prostate cancein bone restructuring caused by prostate cancer.
A key challenge of treating these cancers has been to identify a way of eliminating the abnormal T - cells whilst sparing the healthy ones that play an essential role in providing protection against infections.
Graduate student Megan Radyk and Jason Mills, MD, PhD, led a study revealing that although many cancer therapies target rapidly dividing stem cells, mature cells also seem to play a key role in initiating cancer, at least in forming precancerous lesions.
O - GlcNAc not only plays a key role in signaling, in transcription and in cytoskeletal functions, but it also underlies glucose toxicity in diabetes, is important in neurodegenerative diseases and is important in cancer etiology.
October 21, 1994 Immortalizing agent of tumor cells found in yeast Researchers at the University of Chicago Medical Center have isolated the gene for a component of the elusive molecular machinery that plays a key role in making cancer cells immortal.
Researchers at the University of Chicago Medical Center have isolated the gene for a component of the elusive molecular machinery that plays a key role in making cancer cells immortal, offering scientists a tantalizing target for new anticancer drugs of greater effectiveness and lower toxicity.
«Under her leadership, the Ben May Department has played a key role in basic biological research as well as in bridging basic cancer biology and translational research.
Aug 8, 2008 Two New Predisposition Genes For Breast, Thyroid And Kidney Cancers Could Lead to More Accurate Diagnosis and Earlier Detection of These Cancers Charis Eng, MD, PhD, Sondra J and Stephen R Hardis Endowed Chair of Cancer Genomic Medicine and Chair, GMI, and her team published in the Aug 8, 2008 issue of the American Journal of Human Genetics that germline mutations in SDHB and SDHD, which play key roles in the mitochondria (the cell's power houses), predispose to Cowden and Cowden - like syndromes.
Scientists from the UNC School of Medicine have developed a new tool for studying a key process in cells called G - protein signaling, which plays a central role in the normal functioning of cells and can go awry to cause severe disease, including cancers.
This is why recent work in the field of cancer research has focused on picking apart the complex cellular pathways involved in the development of different cancers and identifying the roles of key proteins involved, with the goal of being able to discriminately and effectively eliminate cancerous cells from the body.
These two histones thus have a key role of epigenetic silencing of tumor suppressor genes in breast cancer (and likely other cancers), suggesting that they may represent new therapeutic targets.
The role of new genetic pathways in cancer biochemistry (the genome mutation profiles), the identification of the key targets and their validation, as well as utilization of new knock - out or knock - in animal models for such studies are among topics that will be discussed.
Scientists discover that a regulator of inflammation plays a key role in the proliferation of lung cancer cells
Type - I interferons (IFNs) play a key role in the immune defences against viral and bacterial infections, and in cancer immunosurveillance.
Dr. Mayer is a key component of the Vanderbilt - Ingram Cancer Center (VICC) Breast Cancer Program, where her role is to implement and conduct investigator - initiated, mechanism - based clinical and translational trials in breast cancer, focusing in novel diagnostic and therapeutic approCancer Center (VICC) Breast Cancer Program, where her role is to implement and conduct investigator - initiated, mechanism - based clinical and translational trials in breast cancer, focusing in novel diagnostic and therapeutic approCancer Program, where her role is to implement and conduct investigator - initiated, mechanism - based clinical and translational trials in breast cancer, focusing in novel diagnostic and therapeutic approcancer, focusing in novel diagnostic and therapeutic approaches.
The CXCR4 receptor and its ligand CXCL12 (also named stromal cell - derived factor 1, SDF1) have a critical role in chemotaxis and homing, key steps in cancer metastasis.
«Although we need to wait for the long - term results of this trial, it's an important «proof - of - concept», and hints that there are exciting times ahead for these drugs, which Cancer Research UK played a key role in researching and developing.»
We had a very interesting talk from Lynda Chin, a researcher from the Dana - Farber Cancer institute who played a key role in the analysis of our TCGA glioblastoma publication.
August 15, 2017 New genomic data platform to focus on children's health issues UChicago Medicine to play key role in NIH - funded initiative that concentrates on genetic flaws related to pediatric cancer, birth defects
GSK3β, the first neighbour of β - catenin is a central, highly multi-functional protein known as a key protein difficult to inhibit without causing side effects and toxicity.41 In glioblastoma and NSCLC cancer, previous studies found that the decreased level of FRAT1 influences the GSK3β activity to phosphorylate β - catenin and by that, inhibit the WNT pathway.39, 40 The role of FRAT1 in colon cancer is less known but based on its function in other cancer types and its special influencing position in colon cancer signalling, we point out its relevance as a potential target in colon cancer therapy (Fig. 3dIn glioblastoma and NSCLC cancer, previous studies found that the decreased level of FRAT1 influences the GSK3β activity to phosphorylate β - catenin and by that, inhibit the WNT pathway.39, 40 The role of FRAT1 in colon cancer is less known but based on its function in other cancer types and its special influencing position in colon cancer signalling, we point out its relevance as a potential target in colon cancer therapy (Fig. 3din colon cancer is less known but based on its function in other cancer types and its special influencing position in colon cancer signalling, we point out its relevance as a potential target in colon cancer therapy (Fig. 3din other cancer types and its special influencing position in colon cancer signalling, we point out its relevance as a potential target in colon cancer therapy (Fig. 3din colon cancer signalling, we point out its relevance as a potential target in colon cancer therapy (Fig. 3din colon cancer therapy (Fig. 3d).
Parents play a key role in deciding whether their kids will get the vaccine, and as more millennials reach parenthood, social media may play an even bigger role in cancer prevention, especially concerning HPV vaccination.»
(GETTY IMAGES / HEALTH) Estrogen is probably the hardest - working hormone in a womans body, but it also has a dark side: Research has determined that estrogen often plays a key role in the development of breast cancer, especially after a woman reaches menopause.
Fruits and veggies play key roles in reducing many health risks, including heart disease, stroke, type 2 diabetes, and certain types of cancer.
IL - 6 plays a key role in inflammation, and high levels are tied to harmful proteins that fuel the growth and spread of cancer cells, said Vanamala.
And speaking of metabolic syndrome, one of the key issues addressed in the ``... Breast Cancer» book is the role of excess sugar and carbohydrates in setting the stage for breast cCancer» book is the role of excess sugar and carbohydrates in setting the stage for breast cancercancer.
But now we're starting to see more evidence that the type of cancer in question may not be all that important, because vitamin D appears to play a key role in the development of ALL types of cancer!
DHEA and its metabolite etiocholanolone (also reported by the 24 - Hour Urine Test, see below), inhibit glucose -6-phosphate dehydrogenase (G6PD), an enzyme that plays a key role in anerobic glycolysis, the major route of energy production for cancer cells.91, 92