Sentences with phrase «key unknowns in»

Not exact matches

Such risks, uncertainties and other factors include, without limitation: (1) the effect of economic conditions in the industries and markets in which United Technologies and Rockwell Collins operate in the U.S. and globally and any changes therein, including financial market conditions, fluctuations in commodity prices, interest rates and foreign currency exchange rates, levels of end market demand in construction and in both the commercial and defense segments of the aerospace industry, levels of air travel, financial condition of commercial airlines, the impact of weather conditions and natural disasters and the financial condition of our customers and suppliers; (2) challenges in the development, production, delivery, support, performance and realization of the anticipated benefits of advanced technologies and new products and services; (3) the scope, nature, impact or timing of acquisition and divestiture or restructuring activity, including the pending acquisition of Rockwell Collins, including among other things integration of acquired businesses into United Technologies» existing businesses and realization of synergies and opportunities for growth and innovation; (4) future timing and levels of indebtedness, including indebtedness expected to be incurred by United Technologies in connection with the pending Rockwell Collins acquisition, and capital spending and research and development spending, including in connection with the pending Rockwell Collins acquisition; (5) future availability of credit and factors that may affect such availability, including credit market conditions and our capital structure; (6) the timing and scope of future repurchases of United Technologies» common stock, which may be suspended at any time due to various factors, including market conditions and the level of other investing activities and uses of cash, including in connection with the proposed acquisition of Rockwell; (7) delays and disruption in delivery of materials and services from suppliers; (8) company and customer - directed cost reduction efforts and restructuring costs and savings and other consequences thereof; (9) new business and investment opportunities; (10) our ability to realize the intended benefits of organizational changes; (11) the anticipated benefits of diversification and balance of operations across product lines, regions and industries; (12) the outcome of legal proceedings, investigations and other contingencies; (13) pension plan assumptions and future contributions; (14) the impact of the negotiation of collective bargaining agreements and labor disputes; (15) the effect of changes in political conditions in the U.S. and other countries in which United Technologies and Rockwell Collins operate, including the effect of changes in U.S. trade policies or the U.K.'s pending withdrawal from the EU, on general market conditions, global trade policies and currency exchange rates in the near term and beyond; (16) the effect of changes in tax (including U.S. tax reform enacted on December 22, 2017, which is commonly referred to as the Tax Cuts and Jobs Act of 2017), environmental, regulatory (including among other things import / export) and other laws and regulations in the U.S. and other countries in which United Technologies and Rockwell Collins operate; (17) the ability of United Technologies and Rockwell Collins to receive the required regulatory approvals (and the risk that such approvals may result in the imposition of conditions that could adversely affect the combined company or the expected benefits of the merger) and to satisfy the other conditions to the closing of the pending acquisition on a timely basis or at all; (18) the occurrence of events that may give rise to a right of one or both of United Technologies or Rockwell Collins to terminate the merger agreement, including in circumstances that might require Rockwell Collins to pay a termination fee of $ 695 million to United Technologies or $ 50 million of expense reimbursement; (19) negative effects of the announcement or the completion of the merger on the market price of United Technologies» and / or Rockwell Collins» common stock and / or on their respective financial performance; (20) risks related to Rockwell Collins and United Technologies being restricted in their operation of their businesses while the merger agreement is in effect; (21) risks relating to the value of the United Technologies» shares to be issued in connection with the pending Rockwell acquisition, significant merger costs and / or unknown liabilities; (22) risks associated with third party contracts containing consent and / or other provisions that may be triggered by the Rockwell merger agreement; (23) risks associated with merger - related litigation or appraisal proceedings; and (24) the ability of United Technologies and Rockwell Collins, or the combined company, to retain and hire key personnel.

Saxena informed Kalra on ninth April that these funds had been misplaced because of some unknown assault in keeping with the police assertion which says «Because the personal keys are stored with Dr Amitabh Saxena, we really feel that he's making a false story to divert our consideration and he may need a job to play on this complete incident.»

In our comprehensive review of the GOP tax bill which was scheduled to be unveiled tomorrow, we noted the following key caveat «There are a lot of unknowns in this process, the biggest of which — of course — is whether the bill will be delayed from its scheduled Wednesday appearance.&raquIn our comprehensive review of the GOP tax bill which was scheduled to be unveiled tomorrow, we noted the following key caveat «There are a lot of unknowns in this process, the biggest of which — of course — is whether the bill will be delayed from its scheduled Wednesday appearance.&raquin this process, the biggest of which — of course — is whether the bill will be delayed from its scheduled Wednesday appearance.»

As we wrote back in June about the systemic threat created by passive strategies: «If a key sector failure, a geopolitical crisis, or even an unknown, black box bias pulls an algorithmic risk trigger, will the herd run all at once?»

The term itself is unknown to most U.S. citizens yet low - intensity conflict is the key strategy by which the United States seeks to project its power in the third world in order to protect perceived vital interests.

Going from the unknown levels of French football to the top of his game with Arsenal in the Premier League, Koscielny is an example that hard work, dedication and investment are key to seeing a player develop at a club.

KEY RETURNEES WRJeff Samardzija (Sr.) Went from unknown to first - team All - America in» 05, with77 receptions and 15 TDs LB Maurice Crum Jr. (Soph.)

The measure means that while the Electoral Commission can now publish information about any donations since July last year — and in the future — it is still banned from sharing key information about donations to Northern Irish parties during a period which included the European referendum, when the DUP received # 435,000 for their Brexit campaign from an unknown source via a secretive group in Glasgow whose chair set up a company in 2013 with the former head of the Saudi intelligence service.

They also identified genomic hotspots that seem to play a key role in adaptation and survival, with many having an unknown function.

A key breakthrough in the research came when the scientists discovered something that was previously unknown — a molecular mechanism in the Fanconi anemia DNA repair pathway apparently makes T - ALL resistant to chemotherapy.

Changes in key genes clearly define four previously unknown conditions within the umbrella diagnosis of schizophrenia, according to a study led by researchers from NYU Langone Medical Center published online April 28 in EBioMedicine, a Lancet journal.

GABA has been known for decades to be a key neurotransmitter in the brain, a chemical that nerve cells use to communicate with each other, but its role in the pancreas was unknown until the 2011 paper by Drs. Prud «homme and Wang.

Published a month apart in PLOS Pathogens, the studies from Professor Ethan Bier's laboratory used a series of experiments to identify key pathways and mechanisms previously unknown or overlooked in the body's defenses.

In February, a H10N8 strain previously unknown in humans caused one death in China and in April, an oubreak of bird flu on a California quail farm prompted five key export markets to bar imports of poultry from the statIn February, a H10N8 strain previously unknown in humans caused one death in China and in April, an oubreak of bird flu on a California quail farm prompted five key export markets to bar imports of poultry from the statin humans caused one death in China and in April, an oubreak of bird flu on a California quail farm prompted five key export markets to bar imports of poultry from the statin China and in April, an oubreak of bird flu on a California quail farm prompted five key export markets to bar imports of poultry from the statin April, an oubreak of bird flu on a California quail farm prompted five key export markets to bar imports of poultry from the state.

And they found that key areas in chromosomes, the centromeric regions, are 25 % smaller in the benign fungus, for reasons unknown but that offer «an excellent starting point for follow - up investigations,» notes Kim Hammond - Kosack, a molecular plant pathologist at Rothamsted and leader of the research team.

One of the great unknowns in the history of life is the part that Antarctica may have played in the evolution and migration of vertebrates (backboned animals) during the key time interval that spans the end of the Age of Dinosaurs and the beginning of the Age of Mammals (the Cretaceous — Paleogene or K — Pg, between 100 and 40 million years ago).

However, given that APOE plays key functions in peripheral immune cells that are very similar to microglia (eg, macrophages), it is surprising that the role of APOE in microglia is practically unexplored and remains largely unknown.

Among their results, the researchers have identified enzymes that may allow D. vulgaris to produce energy in two previously unknown ways, and identified the key enzymes involved in protecting D. vulgaris from exposure to oxygen.

These efforts have resulted in the discovery of previously unknown human T cell epitopes that may be key in the initiation of allergic responses, and to the development of biochemical and bioinformatic tools that have been used to map the human T cell response to a large panel of common allergens.

Key to the project are lab and bioinformatics exercises that will give students the unique opportunity to work with Cold Spring Harbor Laboratory researcher David Jackson in determining the cellular analysis of Arabidopsis genes of unknown function.

The bromodomain containing protein 9 (BRD9) has been reported as a component of the switch / sucrose non-fermentable (SWI / SNF) brahma - related gene 1 - associated factor (BAF) complex, which plays a key role in chromatin remodelling and transcription control [1] although the precise biological role is unknown.

Truly understanding a circuit requires identifying and characterizing the component cells, defining their connections with one another, monitoring and recording their activity patterns — and we are still at the point where much work remains to identify the key differences in a vast array of unknown neurons.

Stress resistance has not been assessed however and so the biological relevance of this finding is currently unknown.32 Several IER trials (75 - 85 % ER on restricted days) in overweight / obese populations have reported reductions in various markers of oxidative stress 37, 41, which in one study was accompanied by a complementary increase in the anti-oxidant uric acid.37 In a direct comparison of IER (75 % ER for two days / week) and CER, both ER strategies displayed equal efficacy in reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directioin overweight / obese populations have reported reductions in various markers of oxidative stress 37, 41, which in one study was accompanied by a complementary increase in the anti-oxidant uric acid.37 In a direct comparison of IER (75 % ER for two days / week) and CER, both ER strategies displayed equal efficacy in reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directioin various markers of oxidative stress 37, 41, which in one study was accompanied by a complementary increase in the anti-oxidant uric acid.37 In a direct comparison of IER (75 % ER for two days / week) and CER, both ER strategies displayed equal efficacy in reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directioin one study was accompanied by a complementary increase in the anti-oxidant uric acid.37 In a direct comparison of IER (75 % ER for two days / week) and CER, both ER strategies displayed equal efficacy in reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directioin the anti-oxidant uric acid.37 In a direct comparison of IER (75 % ER for two days / week) and CER, both ER strategies displayed equal efficacy in reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research DirectioIn a direct comparison of IER (75 % ER for two days / week) and CER, both ER strategies displayed equal efficacy in reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directioin reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directioin the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directioin the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directioin the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directioin which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directioin AOPP in both groups after three months.48 Summary and Future Research Directioin both groups after three months.48 Summary and Future Research Directions

Although the reasons for reduced vitamin D status in the high dose group are unknown, the key point here is that vitamin D status and melatonin production were inversely correlated.

In fact, NOW is currently the only natural product manufacturer to invest in and install the new Dupont ™ RiboPrinter ® System, which uses DNA - fingerprinting technology to identify specific strains of bacteria as well as unknown microorganisms, to better verify the identity and purity of our key probiotic productIn fact, NOW is currently the only natural product manufacturer to invest in and install the new Dupont ™ RiboPrinter ® System, which uses DNA - fingerprinting technology to identify specific strains of bacteria as well as unknown microorganisms, to better verify the identity and purity of our key probiotic productin and install the new Dupont ™ RiboPrinter ® System, which uses DNA - fingerprinting technology to identify specific strains of bacteria as well as unknown microorganisms, to better verify the identity and purity of our key probiotic products.

How colloidal silver might be «used up» during the process, thus becoming ineffective (such as in the 1:1 mixture) is unknown, and may be key in understanding exactly how silver works against pathogens.

New to the cast, or at least previously unreported are Tom Wilkinson («Michael Clayton «-RRB- and Tony Revolori, a relative unknown who plays a key young boy character in the movie.

«A BRONX TALE»: When Robert De Niro offered to buy the rights to the autobiographical one - man play «A Bronx Tale» from its largely unknown creator, actor - writer Chazz Palminteri, in order to make his directorial debut, it is said that Palminteri would not sell unless he was allowed to both write the screenplay and play one of its key roles.

The planet destroyer Steppenwolf (Ciaran Hinds) has descended from the interstellar unknown and laid waste to both the hidden island of Themyscira and the lost underwater city of Atlantis in search of powerful artifacts known as «Mother Boxes,» a third one buried in the bowels of the earth by mankind 5,000 years ago the last remaining key that will help this demon cover the world in fire and darkness.

Story detail remain unknown but everyone still alive from the first movie makes a return while several new key mutants (including Domino) get introduced in a film that will setup not only Deadpool 3, but the long - awaited R - rated team - up, X-Force.

There are a number of phonics activities building up through the alphabet, key graphemes, tongue twisters and an unknown text to say out loud accurately (a famous French song) • Powerpoint of the lesson • Sound file for the song • Strategies for students to help improve their pronunciation • Self and peer assessment I have also included a doubled sided colour learning mat that can be laminated to support students in writing longer and more complex sentences.

and poems like Marchetter Chute's Drinking Fountain provide students ample opportunity to practice their reading skills and to meet reading standards in literature such as being able to «ask and answer questions about unknown words in a text» and «With prompting and support, retell familiar stories, including key details.»

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date unknown to me, you can learn more at the website linked in my name) I want to broaden my reach, and I know long - term, an agent is key.

But sometimes through the complication and the inevitable unknowns that come with investing, one or two key variables emerge as the only things that really matter in the end.

I think the above blog post nailed the key unknown and problem which is how much of the business will continue to transition to lower margin services and products, along with how much will the business be impacted by further cuts in defense responding.

As with anything unknown in life, if you don't know how to communicate with your dog appropriately and effectively, education is the key.

LOS ANGELES (Mar. 4, 2016)-- A new trailer for STAR OCEAN ®: Integrity and Faithlessness ™, the latest game in the series, foreshadows an unknown menace headed for the underdeveloped planet of Faykreed, where Fidel Camuze, his childhood friend Miki Sauvester, and a mysterious young girl named Relia, who holds the key to the story, get drawn into a battle that may change the fate of the planet.

Pompidou Centre (PC): The exhibition explores an unknown chapter in art history — the phenomenon of the Vitebsk At School which brought together the key figures of the Russian avant - garde in the same place during a relatively short period of time.

Francis Alÿs runs into the eye of a tornado; Bas Jan Ader sails out to sea in search of the miraculous to tragically never return; ORLAN undergoes plastic surgery; Marina Abramovic's points a a bow and arrow at her own heart; Pedro Reyes creates musical instruments out of firearms and Ruth Proctor freefalls in the gallery... Walk into a physical, audio, intellectual and emotional unknown with over 70 pivotal works from the mid-20th century to the present day by major international artists including Marina Abramović, Eva Hesse, Yves Klein, Marcel Duchamp, Andreas Gursky, Gerhard Richter, Carsten Höller, Yoko Ono, Fischli & Weiss, Jose Dávila, ORLAN, Chim ↑ Pom and Ai Weiwei, as well as key works by JMW Turner and Maze: Risk edition by Jasmin Vardimon Company.

The key developments in the history of abstract art, from relatively unknown artists such as Hilma af Klint to giants of the movement like Mondrian, Klee and Kandinsky

By Proxy includes Marcel Duchamp's assisted readymade With Hidden Noise, a ball of string with an unknown object rattling inside it; embroidery works by Alighiero Boetti; three drawings from John Cage's 1990 series River Rocks and Smoke, in which chance operations are performed by smoke settling in the fibers of the paper; Oliver Laric's Yuanmingyuan Columns, a new work created with 3D scans of Chinese cultural artifacts ensconced in Bergen, Norway; Yoko Ono's seminal chess set and war allegory Play it By Trust; and a work from Xu Zhen's recent Eternity series, which juxtaposes the East and West by mounting headless replicas of key Hellenistic and Buddhist sculptures neck to neck.

However, it is unknown if the temporal variability of these aerosols is a key factor in the evolution of ocean temperature anomalies.

How many more batteries is unknown, how the batteries will work within the system best needs to be determined, and how long the battery systems will survive providing different services is another key element in a cost comparison.

Timing is really the only key unknown with climate risk because any dispassionate investor knows that carbon exposed assets, particularly coal companies, will drop in value at some point.

Such solecisms throughout the IPCC's assessment reports (including the insertion, after the scientists had completed their final draft, of a table in which four decimal points had been right - shifted so as to multiply tenfold the observed contribution of ice - sheets and glaciers to sea - level rise), combined with a heavy reliance upon computer models unskilled even in short - term projection, with initial values of key variables unmeasurable and unknown, with advancement of multiple, untestable, non-Popper-falsifiable theories, with a quantitative assignment of unduly high statistical confidence levels to non-quantitative statements that are ineluctably subject to very large uncertainties, and, above all, with the now - prolonged failure of TS to rise as predicted (Figures 1, 2), raise questions about the reliability and hence policy - relevance of the IPCC's central projections.

In order to manipulate your volume keys and assign them other tasks, you will need to be rooted with the Xposed Framework installed, as well as have «Unknown sources» enabled.

Thus, if your Bitcoin funds are stored in an address that you have not spent from (so the public key is unknown), they are safe against a quantum computer - at least until you try to spend them.

Google's new smartwatch platform is full of potential, but also shrouded in mystery as many of its key functions remain unknown.

Forward - looking information is subject to known and unknown risks, uncertainties and other factors that may cause the actual results, level of activity, performance or achievements of the Company to be materially different from those expressed or implied by such forward - looking information, including but not limited to: risks related to changes in cryptocurrency prices; the estimation of personnel and operating costs; general global markets and economic conditions; risks associated with uninsurable risks; risks associated with currency fluctuations; competition faced in securing experienced personnel with appropriate industry experience and expertise; risks associated with changes in the financial auditing and corporate governance standards applicable to cryptocurrencies and ICO's; risks related to potential conflicts of interest; the reliance on key personnel; financing, capitalization and liquidity risks including the risk that the financing necessary to fund continued development of the Company's business plan may not be available on satisfactory terms, or at all; the risk of potential dilution through the issuance of additional common shares of the Company; the risk of litigation.