Obesity suppresses an important cellular process that prevents
kidney cell damage, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).
Not exact matches
Researchers also are developing techniques for assembling living
cells into working biodevices — which could mean a solution for
damaged internal organs, such as livers, bladders, and
kidneys.
Propylene glycol, in particular, has been known to inhibit
cell growth and has been linked to
kidney damage and liver abnormalities.
It may stunt the physical and mental growth of your baby and can cause considerable
damage to the developing lungs, brain, liver, nervous system,
kidneys and red blood
cells in your baby.
In the longer term, these methods could hasten progress toward replacing a
damaged or diseased
kidney with tissue derived from a patient's own
cells.
The new study suggests that the molecular mass of HES is the major factor responsible for
damage to
kidney cells.
But he also has a team working on the model that occurred to him on the beach: Harvest and grow some healthy
cells from a patient's
damaged kidneys.
If large numbers of white blood
cells get into the lungs or
kidneys, or into transplanted organs, they can cause
damage to healthy tissue.
One promising way to treat diseased or
damaged kidneys is
cell therapies that include the transplantation of renal progenitor
cells, which can then develop into the
cells needed for full recovery.
Other immune
cells are lured to the clog, causing severe inflammation that can
damage the
kidneys, other organs, and the skin.
Harvard Stem
Cell Institute scientists at Brigham and Women's Hospital have found the cellular origin of the tissue scarring caused by organ
damage associated with diabetes, lung disease, high blood pressure,
kidney disease, and other conditions.
Increased glucose processing has long been thought to inflict
damage on the mitochondria (the
cell's power generators), which then produce large amounts of reactive oxygen molecules, which in turn leads to
kidney disease.
This has been evidenced by 1) increased acinar
cell necrosis, 2) increased serum amylase and lipase, 3) higher hepatic
damage, 4) altered liver function test, 5) increased
kidney damage, 6) increase in serum urea and creatinine, 7) altered distribution of pancreatic
cells, 8) increased vacoulation and irregular islets, and 9) mild fibrosis in exocrine regions.
However, a new study from the laboratory of James J. Yoo (Wake Forest School of Medicine, North Carolina, USA) now suggests that regeneration may not require exogenous stem
cells, and biomaterial alone may suffice to repair
damage to the
kidney [3]!
Moreover, the award will fund a tissue regeneration program that helps to identify biological factors that either contribute to or help prevent against
damage that diabetes causes to the body's insulin - producing
cells, eyes,
kidneys and cardiovascular system.
High blood levels of creatinine almost always suggest a
kidney disease, most often including
damaged blood vessels, infections or death of
cells caused by toxins.
Without it, the body's
cells starve and blood sugar levels spike, causing
damage to the heart, eyes,
kidneys, and nerves.
The researchers report that glyphosate causes cancer — particularly of the breast, pancreas,
kidney, thyroid, bladder and liver — and add that it also
damages cell DNA, impairs the absorption of minerals such as manganese and iron, and disrupts fructose metabolism.
Much less common — but more serious — is rhabdomyolysis, in which muscle
cells break down and release proteins such as myoglobin that
damage kidneys.
Even when overdosing for years on end, as Mr. Karason obviously did, there has still been no apparent
damage to his blood
cells, and no disruption whatsoever of heart, liver or
kidney function.
We now know that fructose elevates uric acid, which decreases nitric oxide, raises angiotensin, and causes your smooth muscle
cells to contract, thereby raising your blood pressure and potentially
damaging your
kidneys.
Elevated levels of sugar in your blood can
damage certain
cells in your blood vessels, eyes and
kidneys.
In fact,
kidney beans have antioxidant benefits that rival those of blueberries, a food known for its ability to squelch free radicals that
damage cells.
Fructose elevates uric acid, which decreases nitric oxide, raises angiotensin, and causes your smooth muscle
cells to contract, thereby raising your blood pressure and potentially
damaging your
kidneys.
This protective measure of the
cells saves the
cells from
damage and possible destruction, but long term, insulin resistance can contribute to the development of not just diabetes, but also high blood pressure, cardiovascular disease, and
kidney disease.
A substance called myoglobin within the muscle
cells that is released can result in severe
kidney damage and even
kidney failure.
Unfortunately, if the tubules of the
kidney cells are
damaged, there is a tendency that water may no longer be reabsorbed from the urine.
For cats whose excessive urination is caused by
damage to the
kidney cells, treatment will be quite varied depending on the exact cause of the
damage.
The presence of white blood
cells in urine is indicative of a urinary tract infection which may originate anywhere from the
kidney down to the urethra; an high protein levels in the urine may be due to infection,
kidney disease or other
kidney damage.
The inflammation and immune
cells can begin to
damage the
cells they surround which can begin to cause
damage to organs, most commonly the joints, skin,
kidneys, lungs and brain.
Red blood
cell abnormalities can occur as well as
kidney and / or liver
damage.
A dog's
kidneys can't break down naproxen like a human's can, and the medication will
damage the
kidneys»
cells as they try to metabolize the drug.
According to Quimby, her group's prior research has demonstrated that the stem -
cell treatment could decrease inflammation, promote regeneration of
damaged cells, slow loss of protein through urine, and improve
kidney function.
Just one mothball has the potential to sicken a dog or cat and mothballs that contain naphthalene can cause serious illness, including digestive tract irritation, liver,
kidney and blood
cell damage, swelling of the brain tissues, seizures, coma, respiratory tract
damage (if inhaled) and even death (if ingested).
Researchers at Colorado State University's (CSU) James L. Voss Veterinary Teaching Hospital are seeking feline study participants for a novel stem -
cell therapy that could repair the
damaged organs of cats with chronic
kidney disease.
On the other hand, Colchicum autumnale can be much more serious and may cause severe vomiting, diarrhea (possibly with blood), liver and
kidney damage, and possibly bone marrow
damage, which could then lead to a decrease in white and red blood
cells, as well as platelets.
Clinical and laboratory research has shown that certain herbs can support normal function of the liver,
kidneys, heart and immune system; reduce inflammation and improve blood flow through
damaged tissues; promote the differentiation, aging and death of tumor
cells; and reduce pain.
ACT - activated clotting time (bleeding disorders) ACTH - adrenocorticotropic hormone (adrenal gland function) Ag - antigen test for proteins specific to a disease causing organism or virus Alb - albumin (liver,
kidney and intestinal disorders) Alk - Phos, ALP alkaline phosphatase (liver and adrenal disorders) Allergy Testing intradermal or blood antibody test for allergen hypersensitivity ALT - alanine aminotransferase (liver disorder) Amyl - amylase enzyme — non specific (pancreatitis) ANA - antinuclear antibody (systemic lupus erythematosus) Anaplasmosis Anaplasma spp. (tick - borne rickettsial disease) APTT - activated partial thromboplastin time (blood clotting ability) AST - aspartate aminotransferase (muscle and liver disorders) Band band
cell — type of white blood
cell Baso basophil — type of white blood
cell Bile Acids digestive acids produced in the liver and stored in the gall bladder (liver function) Bili bilirubin (bile pigment responsible for jaundice from liver disease or RBC destruction) BP - blood pressure measurement BUN - blood urea nitrogen (
kidney and liver function) Bx biopsy C & S aerobic / anaerobic bacterial culture and antibiotic sensitivity test (infection, drug selection) Ca +2 calcium ion — unbound calcium (parathyroid gland function) CBC - complete blood count (all circulating
cells) Chol cholesterol (liver, thyroid disorders) CK, CPK creatine [phospho] kinase (muscle disease, heart disease) Cl - chloride ion — unbound chloride (hydration, blood pH) CO2 - carbon dioxide (blood pH) Contrast Radiograph x-ray image using injected radiopaque contrast media Cortisol hormone produced by the adrenal glands (adrenal gland function) Coomb's anti- red blood
cell antibody test (immune - mediated hemolytic anemia) Crea creatinine (
kidney function) CRT - capillary refill time (blood pressure, tissue perfusion) DTM - dermatophyte test medium (ringworm — dermatophytosis) EEG - electroencephalogram (brain function, epilepsy) Ehrlichia Ehrlichia spp. (tick - borne rickettsial disease) EKG, ECG - electrok [c] ardiogram (electrical heart activity, heart arryhthmia) Eos eosinophil — type of white blood
cell Fecal, flotation, direct intestinal parasite exam FeLV Feline Leukemia Virus test FIA Feline Infectious Anemia: aka Feline Hemotrophic Mycoplasma, Haemobartonella felis test FIV Feline Immunodeficiency Virus test Fluorescein Stain fluorescein stain uptake of cornea (corneal ulceration) fT4, fT4ed, freeT4ed thyroxine hormone unbound by protein measured by equilibrium dialysis (thyroid function) GGT gamma - glutamyltranferase (liver disorders) Glob globulin (liver, immune system) Glu blood or urine glucose (diabetes mellitus) Gran granulocytes — subgroup of white blood
cells Hb, Hgb hemoglobin — iron rich protein bound to red blood
cells that carries oxygen (anemia, red
cell mass) HCO3 - bicarbonate ion (blood pH) HCT, PCV, MHCT hematocrit, packed -
cell volume, microhematocrit (hemoconcentration, dehydration, anemia) K + potassium ion — unbound potassium (
kidney disorders, adrenal gland disorders) Lipa lipase enzyme — non specific (pancreatitis) LYME Borrelia spp. (tick - borne rickettsial disease) Lymph lymphocyte — type of white blood
cell MCHC mean corpuscular hemoglobin concentration (anemia, iron deficiency) MCV mean corpuscular volume — average red
cell size (anemia, iron deficiency) Mg +2 magnesium ion — unbound magnesium (diabetes, parathyroid function, malnutrition) MHCT, HCT, PCV microhematocrit, hematocrit, packed -
cell volume (hemoconcentration, dehydration, anemia) MIC minimum inhibitory concentration — part of the C&S that determines antimicrobial selection Mono monocyte — type of white blood
cell MRI magnetic resonance imaging (advanced tissue imaging) Na + sodium ion — unbound sodium (dehydration, adrenal gland disease) nRBC nucleated red blood
cell — immature red blood
cell (bone marrow
damage, lead toxicity) PCV, HCT, MHCT packed -
cell volume, hematocrit, microhematocrit (hemoconcentration, dehydration, anemia) PE physical examination pH urine pH (urinary tract infection, urolithiasis) Phos phosphorus (
kidney disorders, ketoacidosis, parathyroid function) PLI pancreatic lipase immunoreactivity (pancreatitis) PLT platelet —
cells involved in clotting (bleeding disorders) PT prothrombin time (bleeding disorders) PTH parathyroid hormone, parathormone (parathyroid function) Radiograph x-ray image RBC red blood
cell count (anemia) REL Rocky Mountain Spotted Fever / Ehrlichia / Lyme combination test Retic reticulocyte — immature red blood
cell (regenerative vs. non-regenerative anemia) RMSF Rocky Mountain Spotted Fever SAP serum alkaline phosphatase (liver disorders) Schirmer Tear Test tear production test (keratoconjunctivitis sicca — dry eye,) Seg segmented neutrophil — type of white blood
cell USG Urine specific gravity (urine concentration,
kidney function) spec cPL specific canine pancreatic lipase (pancreatitis)-- replaces the PLI test spec fPL specific feline pancreatic lipase (pancreatitis)-- replaces the PLI test T4 thyroxine hormone — total (thyroid gland function) TLI trypsin - like immunoreactivity (exocrine pancreatic insufficiency) TP total protein (hydration, liver disorders) TPR temperature / pulse / respirations (physical exam vital signs) Trig triglycerides (fat metabolism, liver disorders) TSH thyroid stimulating hormone (thyroid gland function) UA urinalysis (
kidney function, urinary tract infection, diabetes) Urine Cortisol - Crea Ratio urine cortisol - creatine ratio (screening test for adrenal gland disease) Urine Protein - Crea Ratio urine protein - creatinine ratio (
kidney disorders) VWF VonWillebrands factor (bleeding disorder) WBC white blood
cell count (infection, inflammation, bone marrow suppression)
Certain types of matches contain chlorates, which could potentially
damage blood
cells and result in difficulty breathing — or even
kidney disease in severe cases.
The toxic results of ingestion can include
damaged red blood
cells, gastrointestinal ulceration, and liver or
kidney failure, among other things.
Signs that taking Valturna may be
damaging your
kidney: • Problems excreting potassium • Metabolic acidosis • Arrhythmias • Hyperkalemia • Ventricular fibrillation • Ventricular tachycardia • Uremia • Pericarditis • Hypocalcaemia • Anemia • Lower red blood
cell count • Appetite loss • Fatigue • Lethargy • Coma