Not exact matches
The researchers then used a 3 - D
cell culture system to coax their mutant and healthy hPSCs down the differentiation pathway into
becoming kidney progenitor
cells and finally the proximal tubule
cells found in
kidney nephrons.
Once it starts, this process is usually irreversible — much as embryonic stem
cells have no alternative but to
become part of a
kidney or cartilage once the biological «switch» is thrown.
Nevertheless, Hahm adds, it appears that «these
cells are producing high amounts of suPAR, which
becomes the mediator that communicates between the immune system and the
kidney.
In the Nature Communications study, UTSW researchers also reported how miR - 17 causes cyst proliferation: the molecule essentially reprograms the metabolism of
kidney cells so that cellular structures called mitochondria use less nutrients, freeing up resources to instead make
cell parts that
become cysts.
A class of therapeutic drugs known as protein kinase inhibitors has in the past decade
become a powerful weapon in the fight against various life - threatening diseases, including certain types of leukemia, lung cancer,
kidney cancer and squamous
cell cancer of the head and neck.
Scientists need to prompt stem
cells to
become kidney, liver or lung
cells, which must then recreate the complex anatomy of a real organ in order to function in a human recipient.
Thus, upon activation by ActD, AKT
becomes an inducer of p53 tumor suppression instead of being a survival factor, as consistently shown in human embryonic
kidney cell lines (293 and 293T), human hepatoma
cell line (HepG2), and mouse hepatoma
cell line (Hepa - 1c1c7).
In addition to increased thirst and urine volume (often called PU / PD, meaning polyuria and polydipsia) over time a cat with CRD may
become anemic, since the
kidneys produce a hormone that stimulates the bone marrow to produce red blood
cells.
Many animals with CRF
become anemic, because the
kidneys are also responsible for stimulating production of new blood
cells.