Sure enough,
the kidney cyst growth was inhibited.
In 2013, Dr. Patel and fellow researchers reported in Proceedings of the National Academy of Sciences that this microRNA cluster indeed appeared to promote
kidney cyst growth.
«The HALT - PKD findings show that people with polycystic kidney disease do not need to take both of the drugs studied to slow their rate of
kidney cyst growth and decline in kidney function.»
Not exact matches
As patients»
kidney volume increases due to
cyst growth, they gradually lose their
kidney function and often develop
kidney failure.
After running the simulations at IU Bloomington, Bacallao confirmed the
cyst growth predictions seen in the virtual
cysts in experiments using real human cells cultivated from polycystic
kidneys from patients at the IU School of Medicine.
The HALT - PKD trial enrolled volunteers to test whether a combination of commonly used FDA - approved drugs, lisinopril and telmisartan, could shrink
kidney cysts and therefore slow progression of ADPKD, a genetic disorder characterized by
growth of fluid - filled
cysts in the
kidneys.
The test drug slowed the
growth of
kidney cysts in two mouse models and in cell cultures of human
kidney cysts, the study showed.
«This is the first treatment that targets a mechanism that directly contributes to the development and
growth of the
kidney cysts in autosomal dominant polycystic kidney disease,» says Vicente Torres, M.D., Ph.D., director of Mayo Clinic's Translational Polycystic Kidney Disease C
kidney cysts in autosomal dominant polycystic
kidney disease,» says Vicente Torres, M.D., Ph.D., director of Mayo Clinic's Translational Polycystic Kidney Disease C
kidney disease,» says Vicente Torres, M.D., Ph.D., director of Mayo Clinic's Translational Polycystic
Kidney Disease C
Kidney Disease Center.
Persians and Himalayans often develop severe cases of
cyst growth inside the
kidneys and eventually lead to
kidney failure.