In a recent study, researchers injected carbon nanotubes into
kidney tumors in mice, and then directed a near - infrared laser at the tumors.
Not exact matches
A few animal studies have raised red flags, including some showing intestinal damage; structural changes
in the
kidneys, pancreas, and spleen; infertility; low birth weights
in mice litters; and cancerous
tumors in rats.
Mice engineered to express Lin28
in their
kidneys developed Wilms
tumor, which regressed when Lin28 was withdrawn, indicating that strategies aimed at blocking or deactivating the gene hold therapeutic promise for children with Wilms.
Recently, we showed that bortezomib treatment
in mice bearing breast and
kidney tumors provided host survival benefit by amplifying
tumor cell caspase8 activation, CD8T cell effector molecules via increased NotchNFkB crosstalk and Fas ligandmediated lysis of
tumor cells.
However, their initial finding demonstrated that progenitor derived from iPSCs generated using lentiviral gene transduction led to the high incidence of highly aggressive
tumors in immunodeficient
mice after transplantation under the
kidney capsule.
Studying cells from the stomach and pancreas
in humans and
mice, as well as
mouse kidney and liver cells, and cells from more than 800
tumor and precancerous lesions
in people, the researchers found when tissue is injured by infections or trauma, mature cells can revert back to a stem - cell state
in which they divide repeatedly.
Thus, upon activation by ActD, AKT becomes an inducer of p53
tumor suppression instead of being a survival factor, as consistently shown
in human embryonic
kidney cell lines (293 and 293T), human hepatoma cell line (HepG2), and
mouse hepatoma cell line (Hepa - 1c1c7).