The team has already successfully repopulated pig
kidneys with human cells, but Ott says further studies are vital to guarantee that the pig components of the organ do not cause rejection when transplanted into humans.
Not exact matches
The researchers detected this SMN long noncoding RNA, or lnc - RNA (pronounced «link RNA») for short, in
human embryonic
kidney cells, brain
cell samples and neurons derived from the stem
cells of healthy people and those
with spinal muscular atrophy type I and II.
Gather and Yun did this
with cells derived from a
human kidney, adding the DNA that codes for GFP.
The researchers inserted the genes for the 25 subtypes into
human kidney cells (an easier feat than working
with real taste
cells).
Tests
with kidney cancer and two
human uterine sarcoma
cell lines, one
with multidrug resistance, showed that 10 of these new compounds were impressively potent against all three
cell lines, the researchers reported.
«First, by genetically modifying the iPS
cells, we created
human kidney tissue in vitro
with green fluorescence.
Before toying
with worms, the S.U.N.Y. Buffalo team tried out their technique on cultures of
human embryonic
kidney cells and neurons from a rat hippocampus, a part of the brain integral to memory.
«This data allows classification of all
human protein - coding genes into those coding for house - hold functions (present in all
cells) and those that are tissue - specific genes
with highly specialized expression in particular organs and tissues, such as
kidney, liver, brain, heart, pancreas.
Human embryonic
kidney (HEK) 293T
cells, a packaging
cell line for lentivirus production, and the preosteoclast
cell line RAW264.7 (ATCC) were maintained in DMEM supplemented
with 10 % FBS and antibiotics.
«The development of a functional
human kidney glomerulus chip opens up an entirely new experimental path to investigate
kidney biology, carry out highly personalized modeling of
kidney diseases and drug toxicities, and the stem
cell - derived
kidney podocytes we developed could even offer a new injectable
cell therapy approach for regenerative medicine in patients
with life - threatening glomerulopathies in the future,» said Ingber.
Each of Emulate's proprietary Organ - Chips — such as the lung, liver, brain, intestine or
kidney — contains tiny hollow channels lined
with tens of thousands of living
human cells and tissues, and is approximately the size of an AA battery.
Organ - Chips — such as the lung, liver, brain or
kidney — are micro-engineered environments lined
with living
human cells and tissues.
Lysates from
human embryonal
kidney (HEK) 293T
cells transfected
with or without the precursor for miR - 142 or miR - 150 were immunopurified using an anti-Ago antibody.
The effect of diet on the gluconeogenic capacity of rat -
kidney - cortex slices [5] Liver and
kidney metabolism during prolonged starvation [6] Unrecognized Pandemic «Subclinical» Diabetes of the Affluent Nations: Causes, Cost and Prevention [7] Carbohydrates and Immune Function [8] Overexpression of glut1 and glut3 in stage I nonsmall
cell lung carcinoma is Associated
with poor survival [9] The in?uence of diet on the mucin carbohydrates in the chick intestinal tract [10] Rat intestinal mucosal responses to a microbial flora and different diets [12] Chronic Ethanol Induced Impairment of Hepatic Glycosylation Machinery in Rat Is Independent of Dietary Carbohydrate [13] Glycosylation in Cellular Mechanisms of Health and Disease [14] Metabolic Aberrations Associated
with Arginine Deficiency [15] Glycerol gluconeogenesis in fasting
humans
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