Sentences with phrase «kill myeloma cells»
The idea is to use the understanding of the pathways that adiponectin uses to kill myeloma cells to create a drug that would do the same thing.
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The researchers then tested the capacity of the modified cells to kill human multiple myeloma cells in laboratory studies and an animal model.
The investigational treatment was combined with chemotherapy and an autologous stem cell transplant — a new strategy designed to target and kill the cells that give rise to myeloma cells.
The researchers grew the modified cells in the lab to increase their numbers and then injected them into an animal model where they again killed human myeloma cells.
The researchers modified a type of human immune cell — called T lymphocytes, or T cells — to target a molecule called CS1, which is found on more than 95 percent of myeloma cells, and to kill the cells.
The new immune system that grows from the donor stem cells can recognize myeloma cells as «foreign» and kill them, which is known as the «graft - vs - myeloma» effect.