Sentences with phrase «kill rifampin»

Intensive efforts also have been underway to develop new, non rifampin - related Mtb RNAP inhibitors that function through binding sites on Mtb RNAP that do not overlap the rifampin binding site and that thus can kill rifampin - resistant TB bacteria.

The results show that AAPs inhibit Mtb RNAP through a binding site that does not overlap the rifampin binding site and thus can inhibit rifampin - resistant Mtb RNAP and kill rifampin - resistant TB bacteria.

Not exact matches

The alterations of the rifampin binding site prevent rifampin from binding to and inhibiting Mtb RNAP, preventing rifampin from killing TB bacteria.

In addition, the Rutgers scientists report the discovery and properties of new, non?rifampin?related compounds — Na - aroyl - N - aryl - phenylalaninamides (AAPs)-- that potently and selectively inhibit Mtb RNAP and potently and selectively kill TB bacteria.They also report the structures of Mtb RNAP bound to an AAP and Mtb RNAP bound to both an AAP and rifampin.