«Once this novel
tumor - homing agent binds to the EphA2 receptor, the oncogene functions as a cancer - specific molecular Trojan horse for paclitaxel, carrying the drug
inside the cancel
cell,
killing the
cell, and thwarting metastasis,» said Maurizio Pellecchia, a professor of biomedical sciences at UCR's School of Medicine who led the research.
When these antibodies were injected into laboratory mice bearing a transplantable
tumor, there was a large proliferation of T -
cells and strong
killing of cancer
cells inside the
tumors!