Sentences with phrase «to kill tumors»

Similarly, it may be possible to identify and validate new targets for drugs that would selectively kill tumor cells with a particular molecular context.

Many standard cancer treatments for pancreatic cancer, including chemotherapy and radiation therapy, kill tumors by damaging their DNA.

Natural killer cells are an important part of our body's immune response, capable of killing tumor cells and viruses, for example.

In mice, the study found this helped kill tumors hiding elsewhere in the body — not just at the site of the injection.

The team believes the method could be ideal for various uses including repairing tissue after a heart attack and delivering cancer drugs to kill tumor cells left behind after surgery.

«However, we found that the drug does not kill tumor cells directly.

The results confirmed that cabazitaxel was more effective at killing tumor cells than docetaxel.

Scientists who are in the process of developing prototypes for potential new anticancer agents that selectively kill tumor cells by interfering with the regulation of intracellular pH, have found that alkaline treatments do NOT have the desired effect - but strongly acidic treatments do.13

An ideal chemotherapeutic agent is expected to specifically kill tumor cells, cause the least amount of undesirable side effect, and leave normal cells unharmed.

His work indicates that this cell surface marker could serve as a target for a novel brain cancer vaccine or T - cell therapies engineered to recognize and kill tumors carrying that neoantigen.

In lab experiments, his group found that PARP inhibitors killed tumors with the defect.

Harvard Stem Cell Institute (HSCI) scientists at Massachusetts General Hospital have a potential solution for how to more effectively kill tumor cells using cancer - killing viruses.

Giving the mice antibiotics helped gemcitabine kill tumor cells, increasing the number of tumor cells going through a type of cell death called apoptosis from about 15 percent to 60 percent or more.

We want to kill these cells that are feeding the tumor rather than just killing the tumor cells, which is less effective.»

In a four - year study conducted on the mouse model in advanced breast cancer metastasis in the eye's anterior chamber, Petty and colleagues found that the new nanoparticle not only killed tumor cells in the eye, but also extended the survival of experimental mice bearing 4T1 tumors, a cell line that is extremely difficult to kill.

Researchers now think that irradiation sometimes kills tumor cells in a manner that exposes new antigens to T cells, priming them to target other tumor cells that carry them as well, says Wenbin Lin, a chemist at the University of Chicago in Illinois, and one of the authors of the current study.

When combined with immune checkpoint inhibitors, an existing technology that amplifies T - cell tumor - fighting responses, the nanodisc technology killed tumors within 10 days of treatment in the majority of the mice.

You're hoping that the poison will kill the tumor before it kills the host.»

Radiation kills tumors by initiating DNA damage, but oxygen is required to help finish the job.

Atif, Stein, and colleague Seema Yousuf found that low, physiological doses of progesterone stimulate the growth of glioblastoma tumor cells, but higher doses kill the tumor cells while remaining nontoxic for healthy cells.

Dr. Allison: The way the field of immunotherapy is going now is toward combinatorial therapies, where we combine these different immune checkpoints blockers, and also combine these with drugs that actually kill tumor cells.

A virus not known to cause disease kills triple negative breast cancer cells and killed tumors grown from these cells in mice, according to Penn State College of Medicine researchers.

Drug from Mediterranean Weed Kills Tumor Cells Scientists at the Johns Hopkins Kimmel Cancer Center, working with Danish researchers, have developed a novel anticancer drug designed to travel — undetected by normal cells — through the bloodstream until activated by specific cancer proteins.

These tumors are often resistant to radiation because they rapidly outgrow their blood supply and are therefore hypoxic (lacking oxygen), and radiation works better at killing tumors when there is oxygen present.

Even when radiation doesn't totally kill a tumor, it can keep the tumor from growing, which can prolong the dog's life and also improve its quality of life.

M032 kills tumor cells directly through oncolytic replication and then proceeds to infect tumor cells in proximity, continuing the process of tumor destruction.

The macrophages are capable of killing tumor cells or sending out an alarm to T cells of the adaptive immune system that something is amiss.

Iodine 131 is a radioactive isotope that selectively kills the tumor cells, sparing the healthy tissue.

Although doxorubicin can be effective at killing tumor cells, its noxious impact can hurt healthy tissues as well.

«Clearly the zymosan was not killing the tumors directly,» Old says.

Researchers are experimenting with two ways to use gold nanoparticles — in one case, to reduce the collateral damage caused during radiation therapy while increasing effectiveness, and in another, as the targets of laser beams to help kill tumor cells.

Dr. Cripe and his colleagues at The Ohio State University, the University of Pittsburgh School of Medicine and Cincinnati Children's Hospital Medical Center tested how well the oncolytic viral therapy — a cancer - killing form of the herpes simplex virus, called oHSV — infected and killed tumor cells in mice with and without a healthy immune system.

Researchers have injected mice with human breast, ovary, colon, bladder, brain, liver and prostate tumors, and their new drug has killed the tumors every time.

Killing a tumor does nt deprive it of an existence on this earth as a human being.

A century ago, an «electrical bath» was sometimes used to kill tumors.

They discovered that the chemicals and radiation used to kill tumor cells damage the stem cell reservoir in the hippocampus and nearly halt the formation of new neurons in both children and adults.

To more efficiently treat breast cancer, scientists have been researching molecules that selectively bind to cancer cells and deliver a substance that can kill the tumor cells, for several years.

Chemotherapy drugs designed to kill tumors may actually encourage ovarian cancer by stimulating the growth of cells that give rise to the malignancy, a new study finds.

Rubinstein said checkpoint therapies work by cutting the brake cables on the white bloods cells that are inherently able to kill tumor cells.

An experimental drug in early development for aggressive brain tumors can cross the blood - brain tumor barrier, kill tumor cells and block the growth of tumor blood vessels, according to a study led by researchers at the Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James).

Patients received a tandem of lenalidomide, a drug that kills tumor cells, blocks blood vessel growth, and acts on the immune system, and dexamethasone, an anti-inflammatory agent, plus one of three new agents:

Hence, a major goal of cancer scientists has been to develop drugs that prevent Mdm2 from binding to p53, and to thereby activate p53 to kill the tumor cell.

«If the only effect of the virus is to infect and kill the tumor cells, that should be fine.

The researchers found that higher levels of fibronectin allow melanoma cells to form their own protective environment that reduces the ability of BRAF inhibitors to kill tumor cells.

Dr. Folkman's War: Angiogenesis and the Struggle to Defeat Cancer, Robert Cooke (Random House) Judah Folkman is convinced the best way to kill tumors is to cut off their blood supply.

The researchers tested extracts from leaves for the ability to kill tumor cells and parasites and identified the active ingredient for 15 plant species.

CTL119 manufacturing begins with a patient's own T cells, some of which are removed and then reprogrammed in Penn's Clinical Cell and Vaccine Production Facility with a gene transfer technique designed to teach the T cells to target and kill tumor cells.

NK cells find and destroy virally infected cells and also play an important role in detecting and killing tumor cells.

With standard treatments of surgery, chemotherapy and radiation, the median survival time is only 14.6 months, and improvement will only come with the ability to kill tumor cells resistant to standard treatments, according to Alfredo Quiñones - Hinojosa, M.D., a professor of neurosurgery at the Johns Hopkins University School of Medicine and a member of the research team.