Sentences with phrase «killer cells recognize»

David Raulet and Lewis Lanier, separately, show that tumor cells expressing ligands for the natural killer cell activating receptor NKG2D are destroyed by natural killer cells in vivo, establishing a new mechanism for how natural killer cells recognize tumor cells.

«Immune system cells protect against CMV - induced hearing loss in mice: Natural killer cells recognize and bind to viral protein on surface of infected inner ear cells.»

Not exact matches

If so, then different devils» perfectly matched «identity cards» would prevent their killer T cells from recognizing each other's tissues as foreign.

«However, the multiple monobenzone exposures induced only natural killer cells to recognize and attack the pigmented cells.»

Killer T cells recognize tiny, mutated bits of these antigens, known as neoepitopes.

«By treating glioblastoma cells with decitabine, we found that we can unmask targets on the tumor cell that can be recognized by killer T cells.

The immune system also includes natural killer cells (NK cells), which recognize and eliminate tumour or virus - infected cells.

When lysophosphatidic acid (LPA) binds to killer T cells, it acts almost like an «invisibility cloak,» preventing T cells from recognizing and attacking nascent tumors.

Coukos, who is currently leading an ovarian cancer clinical trial sponsored by CRI's Clinical Accelerator, sought to understand why PD - 1 / PD - L1 immunotherapies are often ineffective for these patients, even though ovarian tumors are often infiltrated by «killer» T cells that recognize tumor - specific neoantigens and express high levels of PD - 1.

Using a combination of biochemical and genetic approaches, Darnell's lab discovered that the immune systems of PND patients thwart tumors with what is essentially an antiviral response: The patients» T cells produce CD8 + killer T cells that recognize the neuronal antigens present within their tumors.

His research is related to the work of scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) working to harness the power of killer T cells that can recognize and eliminate cancerous cells.

We found that naive T cells transferred into MHC negative or allogeneic environments often fail to survive because of rejection and / or competition by natural killer (NK) cells, rather than failure to recognize a particular MHC allele.

Killer T - cells first emerge as naïve cells that are out on the lookout for entirely new threats, but in order to do their job, they must assume a specialty, being trained by other immune cells to recognize, seek out, and eliminate a very particular threat.

At the heart of that system are T cells, microscopic killers that recognize and destroy abnormalities.