Her work focuses on identifying and validating protein targets of small molecules capable of
killing Mycobacterium tuberculosis.
Introduction of the vaccine, which contains
a killed mycobacterium — a distant relative of the leprosy organism — began early last month in the state of Gujarat in western India, and it will soon be deployed in Bihar state, in the east.
Not exact matches
Devastating though it sounds, this does present an excellent target for
killing off an infecting
mycobacterium.
The innate system — via stem cells in the bone marrow — mobilizes macrophages, which are a type of white blood cell that swallows and
kills invading bacteria like
Mycobacterium tuberculosis (Mtb) that causes TB.
He added: «
Mycobacteria are incredibly resilient and can remain dormant for many years inside cells where they are exposed to significant levels of free radical damage designed to
kill foreign «invaders.»
But if we could prevent
mycobacteria from hiding in this compartment, or force the bacteria out of it, they would have a hard time not being
killed.
Tumor necrosis factor alpha stimulates
killing of
Mycobacterium tuberculosis by human neutrophils.
TB
kills more people than any other infectious disease, and the causative bacterium,
Mycobacterium tuberculosis, is becoming increasingly resistant to antibiotics used to treat the infection.