To test whether the P210 is the product of the novel 8.5 - kilobase bcr / abl fusion transcript, antibodies were prepared against c - abl and bcr determinants.
CML cells have two novel products: an 8.5 - kilobase RNA transcript containing both abl and bcr and a 210 - kilodalton phosphoprotein (P210) recognized by v - abl - specific antisera.