Sentences with phrase «kilobase region»

A positional cloning approach was used to fine - scale map the ws1 locus to a 13.5 kilobase region.

Here we report a public database of common variation in the human genome: more than one million single nucleotide polymorphisms (SNPs) for which accurate and complete genotypes have been obtained in 269 DNA samples from four populations, including ten 500 - kilobase regions in which essentially all information about common DNA variation has been extracted.

Not exact matches

One of the noncoding de novo mutations was 254 kilobases downstream of FGFR2, in a noncoding region that looks (according to chromatin marks) like a neural crest enhancer.

Negative frequency dependent selection acting at the locus responsible of self - incompatibility in Arabidopsis represents one of the strongest cases of balancing selection, and yet we have shown that its indirect effects on neighboring regions are restricted to a few kilobases [2].

In truth, human chromosomes are tightly organized and packed into the nucleus, a situation which causes physical interaction between regions that might be hundreds of kilobases apart.

The human T cell receptor beta (TRB, previously known as TCRB) gene locus on chromosome 7 (7q34) includes 65 Vb (variable) gene segments, followed by two separate clusters of genes each containing a Db (diversity) gene, several Jb (joining) genes, and a Cb (constant) region spread over 685 kilobases.

Unfortunately, LOH regions tend to be kilobases or megabases in size, containing dozens or hundreds of genes, and identifying which ones are truly affected in terms of cancer remains challenging.

Lindblad - Toh and a large group of investigators [31] compared the haplotype structure of the genome of the Boxer and 10 other breeds and found regions of linkage disequilibrium extending over several megabases within a breed and tens of kilobases between breeds.