Sentences with phrase «kinase pathway regulates»

p38 MAP kinase pathway regulates apoptosis through phosphorylation and up - regulation of BimEL: ProQuest.

LKB1 - NUAK1 kinase pathway regulates terminal axon branching through mitochondrial trafficking.

Not exact matches

In this pathway, dopamine - and an adenosine 3 ′, 5 ′ - monophosphate (cAMP)-- regulated phospho - protein of 32 kilodaltons (DARPP - 32) is phosphorylated or dephosphorylated at three sites, in a pattern predicted to cause a synergistic inhibition of protein phosphatase — 1 and concomitant regulation of its downstream effector proteins glycogen synthesis kinase — 3 (GSK - 3), cAMP response element — binding protein (CREB), and c - Fos.

MicroRNA -7-5p regulates the proliferation and migration of intestinal epithelial cells by targeting trefoil factor 3 via inhibiting the phosphoinositide 3 - kinase / Akt signalling pathway.

Molecular genesis of cutaneous melanoma pathways; rous avian sarcoma homologue (Ras); v - raf murine sarcoma viral oncogene homologue B1 (BRAF); mitogen - activated protein kinase (MEK); extracellular signal - regulated kinase (ERK); microphthalmia transcription factor (Mitf); phosphatidylinositol - 3 kinase (PI3K); murine v - akt oncogene homologue (Akt).

PACAP regulates immediate catecholamine release from adrenal chromaffin cells in an activity - dependent manner through a protein kinase C - dependent pathway.

In the last decade the identification of genetic drivers of melanoma cell which regulate proliferation and survival - such as BRAF and other activators of the MAP - kinase pathway - along with the recent development of immunotherapy has taken away in many cases the invasive treatment of melanoma as an option.

Synapses are regulated by the cytoplasmic tyrosine kinase Fer in a pathway mediated by p120catenin, Fer, SHP - 2, and β - catenin.

ABL kinases regulate the expression of genes in the JAK / STAT and Hippo pathway signatures in metastatic breast cancer cells.

This is a very important lipid, that actually is involved in signaling, to many other kinases, and the key kinase that through this pathway gets activated is Akt; and Akt is a very important kinase that regulates many other factors.

We study the signal transduction pathways regulating cell growth and proliferation, with an emphasis on kinase enzymes.

This is quite a complex pathway and I don't have time to go through details, but just briefly, glucose metabolism is regulated by insulin, so is lipid metabolism and this is one of many pathways where insulin activates a number of kinases, but particularly Akt.

We further demonstrate that the cAMP - responsive enhancement of Oct4 activity is at least partially regulated through the p38 MAP kinase pathway.

Pterostilbene also increases activity of the AMPK (adenosine monophosphate - activated protein kinase) pathway, which regulates production of energy, reduces chronic inflammation, lowers levels of blood sugar and fats in the blood, and reduces stores of body fat.

Insulin - like growth factor - 1 (IGF - 1) inversely regulates atrophy - induced genes via the phosphatidylinositol 3 - kinase / Akt / mammalian target of rapamycin (PI3K / Akt / mTOR) pathway

mTORC1 is the central component of the insulin - signaling cascade [insulin / insulin - like growth factor (IGF)-- phosphatidylinositol 3 - kinase (PI3K) pathway)(Fig. 1) that regulates protein synthesis and mRNA translation through 2 primary mechanisms: 1) inactivation of the repressor of mRNA translation, eukaryotic translation initiation factor 4E - binding protein 1 (eIF4E - BP1), and 2) the activation of 70 - kDa ribosomal protein S6 kinase.