Sentences with phrase «kinesins as»
Not exact matches
The researchers found that AS - 2 binds strongly to the kinesin motor, preventing it from sticking to a cell's monorails — that is, traveling along microtubules.
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This particular active material, originally developed at Brandeis University, borrows elements of cellular machinery, with bundles of rod - like microtubules forming the filaments, kinesin motor proteins acting as the engines, and ATP as the fuel.
Proteins called kinesins, for example, are natural nanomotors that support cellular functions such as mitosis (the chromosomal process that creates two nuclei from one parent nucleus) and meiosis (when the number of chromosomes per cell is reduced by one half).
As many kinesin - 5 molecules work together directing microtubules, they become the governing force of the spindle formation.
The researchers found that the motor protein kinesin - 5 (green) helps prepare the spindle by organizing its filaments, or microtubules, (red) by pushing them or acting as a brake.
Kinesin - 5 has been identified as a target for drugs to treat cancers that involve uncontrolled cell division, such as colorectal cancer, Al - Bassam said.
Originally identified as a protein essential for mitosis in fungi, kinesin - 5 was first purified about 20 years ago by Scholey's lab who found that it is unusual because it has motor units at both ends, allowing it to link two microtubules and walk them past each other.
His lab provided the first molecular descriptions of kinesin structure and organization, and has recently discovered important links between transport processes and diseases such as Alzheimer's disease and Huntington's disease.
As a graduate student at the European Molecular Biology Lab in Heidelberg he used cryo - EM to study kinesin motors, capturing snapshots that show how kinesin «walks» along a microtubule.
The investigators showed that kinesin movement corresponds to traffic from the center of a nerve cell to its axonal tips — and a different motor in the squid's cytoplasm, which was subsequently identified as dynein, travels in the opposite direction.