Sentences with phrase «knockdown with»

Play can knockdown with this can toss game.

In contrast, in five luminal breast cell lines, MELK knockdown with equivalent efficiency did not result in obvious inhibition on cell growth (Figure 5E, Figure 5 — figure supplement 1A, B).

TAZ knockdown with two distinct shRNAs decreased the phosphorylation of STAT5 and, to a lesser extent, total STAT5 protein abundance (fig.

Weissman and his colleagues demonstrated in a paper in Cell that they could typically achieve 90 - 99 % knockdown with minimal off - target effects.

Gerrard himself slammed home an equaliser from a Peter Crouch knockdown with nine minutes of the second half played, but just past the hour mark future Liverpool left - back Paul Konchesky watched his lofted cross sail over Pepe Reina and into the Reds goal to put the Irons back in the lead.

-- Slice and dice monstrous foes and travel through 3D environments powered by Unreal Engine 4 — Dominate foes with aerial attacks, throws, and knockdowns with just one tap!

Not exact matches

Custer is a knockdown shooter and heady floor general, finishing the year with a 2:1 assist to turnover ratio.

i think if we by any chance got griezmann that would be awesome, against bus parking teams like norwich we could play with a top 2 with griezmann and giroud they can play very well with eachother and griezmann could get on to girouds flicks and knockdowns and griezmann does play in a top2 at atletico and against the most teams griezmann could play as a lone striker, but anyway i do nt think he will leave atletico

Giroud is a target that works well with players that follow the ball and are in the general vicinity for his knockdowns.

SEE MORE: Spurs & England winger to sign with Premier League punching bag (Video) Mike Tyson falling off a hoverboard — better knockdown than Buster Douglas?

Thiago then headed over and Messi nearly connected with Cesc Fabregas» knockdown at the end of a wonderful move as Barce continued to dominate, but they were rocked when Granada took the lead on 26 minutes.

OG is the best set piece player in the league and creates chances with his knockdowns to players.

Porto took the lead with little more than 10 minutes left, as Joao Mario capped of a fast counterattack to leave Chelsea on the brink of elimination, but Josh Grant levelled in the 86th minute when he fired in from Trevoh Chalobah's knockdown after a Juan Castillo corner.

Marseille came within a whisker of taking the lead in the 42nd minute, Sarr hitting the woodwork with a scrappy volley from Mitroglou's knockdown, only to find themselves behind at the break.

Look at the work Arsenal forward Olivier Giroud does in the buildup, drawing both defenders and then assisting Griezmann with a perfect knockdown header

Burnley's Ashley Barnes went close with an overhead kick from Danny Ings» knockdown and closer still when he so nearly reached a Matthew Taylor cross with a diving header that would have been impossible to stop.

The 20 year old did well, using his strength to hold the ball up, linking up nicely with Pedro who raced down the left, and eventually providing a cushioned knockdown for Michy Batshuayi to score from.

Paulo Dybala made amends for slicing Gonzalo Higuain's knockdown wide from the edge of the area by deftly playing his fellow Argentinian into a one - on - one with Monaco goalkeeper Danijel Subasic.

Like two prized fighters, these two giants of European football sized each other up with gentle jabs before Robin Van Persie delivered a knockdown in the 78th minute.

Cesar Azpilicueta, a surprisingly consistent threat in the penalty box at set pieces today, prodded home from Morata's knockdown in the aftermath of a corner kick to provide Chelsea with a 36th - minute lead.

Berchelt finished the job after the second knockdown in connecting with several hard...

With just over six months until the Democratic primary, no credible challenger — a person with some combination of name recognition, a political base, governmental experience and the funding to wage a knockdown campaign — has emerged to take on de Blasio, despite all his problWith just over six months until the Democratic primary, no credible challenger — a person with some combination of name recognition, a political base, governmental experience and the funding to wage a knockdown campaign — has emerged to take on de Blasio, despite all his problwith some combination of name recognition, a political base, governmental experience and the funding to wage a knockdown campaign — has emerged to take on de Blasio, despite all his problems.

«We developed Drosophila lung cancer models by targeting Ras alone and in combination with PTEN knockdown in the tracheal system of the fruit fly,» says Cagan, PhD, Professor in the Department of Developmental & Regenerative Biology, Senior Associate Dean of the Graduate School of Biomedical Sciences, and Director of the Center for Personalized Cancer Therapeutics at Icahn School of Medicine at Mount Sinai.

«If the gene has been blocked in a knockdown, blood vessels do not develop normally,» explains Andrea Rossi, together with Zacharias Kontarakis first author of the study.

When «knockdown» animals are treated with emilin 3B after egfl7 has been blocked, blood vessels develop almost normally.

Knockdown of approximately 75 % was seen at day 7 at a dose of 0.1 mg per kilogram and 90 % at day 14 at a dose of 0.3 mg per kilogram, with more than 70 % suppression persisting at day 28 in the high - dose group.

In nonhuman primates that received ALN - TTR01 in a single dose of 1.0 mg per kilogram, the mean percent transthyretin knockdown at the nadir level (7 days after administration) was approximately 50 %, with recovery to the baseline level by day 28 (Fig.

Further studies of ALN - TTR02 are needed to examine the clinical efficacy and safety of long - term transthyretin knockdown in patients with familial amyloidotic polyneuropathy.

This could be due to incomplete gene knockdown, the presence of another body pigment in analogy with the Drosophila eye, or accumulation of colored intermediates in ommochrome biosynthesis (for instance, kynurenine imparts a yellow color to the eyes of deep - sea fish; Thorpe et al., 1992).

Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion.

As the level of gene activity knockdown associated with transgenic RNAi depends on the level of expression of the hairpin constructs, we generated a number of derivatives of our initial vector, called the «VALIUM» series, to improve the efficiency of the method.

Bone marrow cells cultured with conditioned medium derived from ABL1 / ABL2 knockdown 1833 and SKBR3 breast cancer cells had decreased numbers of TRAP + cells compared to the control groups (Fig. 5, B and C, and fig.

(K) Representative immunoblots of 1833 cells transfected with control shRNA, shRNA against ABL1 (shABL1), ABL2 (shABL2), and shRNA # 2 against both ABL1 and ABL2 (shAA # 2) and ABL1 / ABL2 knockdown cells with overexpression of mouse Abl1 / Abl2 (shAA + mAbl1 / Abl2).

Comparison of the transcripts revealed that breast cancer cells with knockdown of ABL2 alone shared a similar gene expression pattern with that of the ABL1 / ABL2 double - knockdown cells (Fig. 6A and fig.

Moreover, three - dimensional (3D) μCT reconstruction of the tibia revealed that mice injected with control cells had a significantly higher degree of osteolysis with a decreased ratio of bone volume to total volume compared to mice injected with ABL1 / ABL2 knockdown breast cancer cells (Fig. 4, E and F).

The overall score encompass several factors: reproducibility of the antibody staining in different cell lines (and if signal strength correlates with RNA expression levels); assays for enhanced antibody validation by using antibodies binding to different epitopes on the same target protein (independent antibodies), by knockdown / knockout of the target protein (genetic methods) and by matching of the signal with a GFP - tagged protein (recombinant expression); experimental evidence for location described in literature.

Notably, analysis of cell lysates from ABL2 - depleted and ABL1 / ABL2 double - knockdown breast cancer cells showed a greater reduction of the phosphorylation of CrkL compared to cells with knockdown of ABL1 alone (Fig. 2K).

Knockdown of Nrf2 expression resulted in reduced induction of HMOX1 by HPP - 4382, CoPP and bardoxolone, consistent with the well - characterized role of Nrf2 as a critical activating transcription factor for HMOX1.

Knockdown of dynamin - binding protein or Tuba results in abnormal kidney development and other aberrant phenotypes in zebrafish models (middle and right panels) compared with controls (left panel).

(E) MELK knockdown induces the accumulation of cells with 4n DNA content and G2 / M arrest.

To study the impact of MELK knockdown on tumor growth, mice were randomly sorted into groups on the second day of injection, and were untreated or treated with doxycycline (2 mg / ml in 5 % dextrose in drinking water, refreshed twice a week) for the duration of the study.

Experiments in Muc1 knockout mice and mice with Muc1 knockdown have shown that under Helicobacter infection, mice deficient in Muc1 develop far more cancer - promoting inflammation than normal mice.

From the photographer, The venue (Knockdown Center in Queens, New York) was my inspiration + starting off point — it's a partially restored glass factory with a beautiful industrial feel (and the lighting was amazing!).

Instead of putting itself best foot forward this game offers a complete arcade fighter experience against humans, and AI fully equipped with static manufactured drama with its sudden and most time random flash knockdowns, to strikes that deal significant damage not causing the fighter to show any visual que that it was effective.

Her repartee with Deadpool is knockdown funny.

You can pick a variety of tracks with different modes like race, battle, stunts and knockdown.

There's a light and medium attack, as well as a strong attack that serves as more of a combo ender / knockdown button that you can play with and cancel into special moves.

The first application of flea granules should be used with a liquid form of insecticide spray that gives quick «knockdown».

2K Games will offer up their own knockdown - dragout clash for the PS4 this week with the release of WWE 2K18.

While this helps open up the game to more casual players, the auto combos aren't exactly viable as the more intermediate to advanced players can play around with jump cancels, hard knockdowns and other methods to extend combos to do more damage.