Sentences with phrase «knockin mouse lines»
Disease progression was compared in three knockin mouse lines with similar CAG repeat expansion lengths of approximately 190 repeats, were compared at 2, 4, 6 and 10 months of age utilizing PsychoGenics proprietary cubes platform technologies: PhenoCube ®, Smart Cube ® and Neurocube ® as well as standard behavioral testing paradigms including Open Field and Tapered Balance Beam.
http://www.psychogenics.com/ Not exact matches
Development of innovative mouse lines by targeted genome modification (knockin - knockout (KI / KO) approaches).
Given that many recent studies of B cell biology take advantage of Ig - transgenic (or knockin equivalent) mice for their entire analysis, we do not feel that our use of the approach as one part of the present study is out of line with currently accepted practice in the field.