Sentences with phrase «knowledge of the human genome»

Careful attention to phenotyping diseases, facilitated by our knowledge of the human genome and computational analysis, has allowed observant physicians and physician - scientists to identify and categorize diseases in a manner that has informed basic science, given it new contexts, and in many instances provided important new directions for investigation.

«This work is a great example of how knowledge of the human genome sequence can lead to valuable insights into human diseases.

The most likely outcomes from our knowledge of the human genome will continue to orbit around sequencing techniques and basic biological discoveries.

«The time is right for pursuing the complex question of healthy aging given the rapid advances in analytical technologies and the expanding knowledge of the human genome and microbiome and their interactions.

This innovation could revolutionize medicine and our knowledge of the human genome.

Despite the significant insights gained from large - scale studies designed to interpret this instruction book, including HapMap, Encyclopedia of DNA Elements (ENCODE), and genome - wide association studies (GWAS), our knowledge of the human genome remains far from complete.

Not exact matches

The, members of the workshop believe that knowledge gained from mapping and sequencing the human genome can have great benefit for human health and well being.

With the advances in knowledge that are almost certain to be gained from the Human Genome Initiative — or, if its critics should win the day and it lose support, from more piecemeal genetic - research — we will know more and - more about genetic factors causally related to health and disease and to other important aspects of life, such as intelligence and emotional states.

The principles that have emerged thus far are these: We should seek new knowledge of our genes (and we can say this without deciding whether the Human Genome Initiative is the wisest and most cost - effective way to do so) We should seek therapies for the genetic disorders that afflict many people.

Since the completion of the Human Genome Project in 2003, scientists have expanded their knowledge of how living cells work with new approaches including genomics, proteomics, and systems biology.

The partitioning of humans into biological races was permissible when the knowledge of our genetic inheritance was based on less than 0.1 percent of the human genome.

In this era of the human genome map, it would seem a simple matter to pinpoint the bit of DNA responsible for each disease and use that knowledge to find a cure.

«Having the genome sequence is like having part of the instruction manual,» says study author Richard Wilson of Washington University in Saint Louis (W.U.), echoing the famous 2000 comment of then Human Genome Project leader Francis Collins, who called knowledge of our genome a «glimpse of our instruction book.&genome sequence is like having part of the instruction manual,» says study author Richard Wilson of Washington University in Saint Louis (W.U.), echoing the famous 2000 comment of then Human Genome Project leader Francis Collins, who called knowledge of our genome a «glimpse of our instruction book.&Genome Project leader Francis Collins, who called knowledge of our genome a «glimpse of our instruction book.&genome a «glimpse of our instruction book.»

He added: «The sequencing of genomes from this key region will have a major impact on the fields of palaeogeneomics and human evolution in Eurasia, as it bridges a major geographic gap in our knowledge.»

The human genome is diploid, and knowledge of the variants on each chromosome is important for the interpretation of genomic information.

During those years, the way we study fundamental biological processes underwent a major shift that has now culminated in sequenced human genomes, knowledge of many cellular processes, and a clear path to unraveling roles for individual molecules.

Each of the working groups is responsible for developing a proposal for a set of genomes to sequence that would advance knowledge in one of three important scientific areas: identifying areas in genetic research where the application of high - throughput sequencing resources would rapidly lead to significant medical advances; understanding of the human genome; and understanding the evolutionary biology of genomes.

No doubt, knowledge of the mouse genome will help scientists design more effective mouse models for human disease and disorder.

Building on the foundation laid by the Human Genome Project, Dr. Collins is now leading NHGRI's effort to ensure that this new trove of sequence data is translated into powerful tools and thoughtful strategies to advance biological knowledge and improve human heHuman Genome Project, Dr. Collins is now leading NHGRI's effort to ensure that this new trove of sequence data is translated into powerful tools and thoughtful strategies to advance biological knowledge and improve human hehuman health.

ASHG and its members are committed to become fluent in the language of the genome, understand human variation, and promote the public health as well as transfering new knowledge to the next generation of genetics professionals and the public in order to improve clinical practice.

This knowledge, which will only be rapidly obtainable in the model organisms, will allow the reduction of most of the approximately 70,000 individual genes encoded by the human genome into a much smaller number of multicomponent, core processes of known biochemical function.

«It's been 10 years since the Human Genome Project was declared «complete,» but the amount of genomic knowledge we've gleaned since then — in large part due to advances in bioinformatics and supercomputing — have catapulted us far beyond what we thought we knew,» added Dr. Pollard.

Over the past two decades, we've been told that a new age of molecular medicine — using gene therapy, stem cells, and the knowledge gleaned from unlocking the human genome — would bring us medical miracles.

A remarkable explosion of new knowledge about the developing brain and human genome, linked to advances in the behavioral and social sciences, tells us that early experiences are built into our bodies and that early childhood is a time of both great promise and considerable risk.

The Institute's aim is to realize the promise of the human genome to revolutionize clinical medicine and to make knowledge freely available to scientists around the world.