It starts with a little -
known compound found in cranberries — just like the unique antioxidants that made cranberry juice so frequently recommended in the first place.
The first recognized antioxidants were vitamin C and vitamin E, but other substances that have powerful antioxidant properties have also been recognized: Selenium, Carotenoids (Beta - carotene, Lutein, Lycopene, Sulforaphane, Zeaxanthin, and Astaxanthin), Bioflavonoids (Anthocyanins, Proanthocyanidins, Quercetin, and Apigenin), Coenzyme — Q10 (Co — Q10), Soy Isoflavones (Genistein and Daidzein), and many other less well -
known compounds found in fruits and vegetables.
Not exact matches
Cauliflower is also jam - packed with phytonutrients (those are the super-charged healthy
compounds found exclusively in plants), such as the familiar beta - carotene, as well as the lesser -
known beta - cryptoxanthin, caffeic acid, cinnamic acid, ferulic acid, quercetin, rutin, and kaempferol (there will be a quiz at the end of this post;) This broad spectrum antioxidant support helps lower the risk of oxidative stress in our cells.
BPA is a
compound that is commonly
found in plastics and that is
known to leach out as the plastic degrades over time.
In your particular example, least of all others would
know that those «novel
compounds» were either not promising, or had to have that little bit of a «different something needed to them», and whoever will
find that, will recognise the importance of the contribution his / her predecessors made.
Who
knows, there may even be useful
compounds hidden away in alternative or traditional medicines that could be
found through a good testing program.
In the new paper, George Cotsarelis of the University of Pennsylvania and his team
found that a
compound known as prostaglandin D2 (PD2) was elevated in the blood of men with male - pattern baldness.
Evidence for such an origin might be bolstered if scientists
find signs of other materials
known to be present in comets, like carbon - based
compounds called organics.
Instead of systematically testing the effects of
known compounds — the pharmaceutical industry's basic model for more than a century — scientists can now investigate backward, combing through genomic data to
find links between specific genotypes and diseases and then screening drug data to identify therapeutic candidates.
Trifluoromethyl groups are
found in a wide variety of
compounds, including such well -
known drugs as Prozac and Celebrex.
Researchers Jan Kramers and Georgy Belyanin
found mineral
compounds unlike anything on Earth, or in
known meteorites or comets, in these fragments from the Hypatia stone, which was picked up in south - west Egypt in the Libyan Desert Glass Field.
While these
compounds did not reduce the amount of protein aggregates, they were
found to reduce the protein's toxicity and to increase the stability of amyloid fibrils — a
finding that lends further evidence to the theory that smaller assemblies of amyloid - beta
known as oligomers, and not the fibrils themselves, are the toxic agents responsible for Alzheimer's symptoms.
They
found that the
compound reduces levels of a key protein —
known as IkappaBzeta — in the IL - 17 inflammatory pathway.
Using data captured by ALMA in Chile and from the ROSINA instrument on ESA's Rosetta mission, a team of astronomers has
found faint traces of the chemical
compound [Freon - 40]--(CH3Cl), also
known as methyl chloride and chloromethane, around both the infant star system IRAS 16293 - 2422, about 400 light - years away, and the famous comet 67P / Churyumov - Gerasimenko (67P / C - G) in our own Solar System.
As far as we have tested in these experiments, we
found that the CDDO
compound had no
known side effects.
The human brain naturally produces and processes
compounds closely related to those
found in Cannabis sativa, better
known as marijuana [see «The Brain's Own Marijuana,» by Roger A. Nicoll and Bradley E. Alger.
When food begins to rot, the smell that we
find repulsive comes from a
compound known as cadaverine.
We now
know that most venoms are complex cocktails of
compounds, with dozens to hundreds of different proteins, peptides and other molecules to be
found in every one.
Researchers at Oregon State University have discovered novel
compounds produced by certain types of chemical reactions — such as those
found in vehicle exhaust or grilling meat — that are hundreds of times more mutagenic than their parent
compounds which are
known carcinogens.
Air monitoring by researchers in 2000
found levels of volatile organic
compounds — highly reactive ozone precursors such as benzene,
known as VOCs — were 10 to 100 times higher than what had previously been estimated.
A study of Italians who consume a diet rich in resveratrol — the
compound found in red wine, dark chocolate and berries —
finds they live
no longer than and are just as likely to develop cardiovascular disease or cancer as those who eat or drink smaller amounts of the antioxidant.
The
compounds,
known as ribonucleoside analogs 8 - azaadenosine, formycin A, 3 - deazauridine, 5 - fluorocytidine and 2» - C - methylcytidine, were
found to stop the replication and spread of HIV by blocking HIV DNA synthesis or by inducing lethal mutagenesis.
They then soaked tiny collagen sponges (which are made from the same protein
found in dentin) in various drugs
known to stimulate Wnt signaling, including tideglusib, a
compound that has been investigated in clinical trials for its potential to treat Alzheimer's and other neurological disorders.
They will
know that
compound X inhibits kinases A, B and C, but
compound Z inhibits kinases D and E. With such a big data set people can easily
find compounds of particular interest to them and
know that the
compounds are annotated with near full - kinome inhibition data.»
One of the Holy Grails in chemical science has been to
find the late - stage, site - specific incorporation of a halogen atom into a complex natural product by replacing an sp ³ C - H bond (one of the most inert chemical bonds
known in an organic
compound) with a C - X bond (X = halogen).
Humans have reduced fevers for thousands of years; Hippocrates recommended extracts of the willow tree bark, which was later
found to contain salicylic acid, better
known as aspirin; Romans, Chinese, and Native Americans used other plants containing similar
compounds.
Using a laboratory technique called chromatography, they
found three new
compounds, one already -
known compound that was identified for the first time in plants and 20 already -
known compounds that were
found for the first time in hops.
They
found that adding one particular set of these
compounds,
known as oligomeric procyanidins (PCs), to the food made the biggest difference in keeping the mice's weight down if they were on high - fat diets.
And despite the methanol in its name, it not the same
compound as the «wood alcohol» most famously
found in moonshine and
known to cause headaches, blindness and even death.
They
found that gas from the sea - soaked samples contained a sulphur
compound known to attract some birds, unlike untreated plastic beads (Science Advances, doi.org/bsz7).
University of Illinois professor of entomology May Berenbaum, who led the study, said that many organisms use a group of enzymes called cytochrome P450 monooxygenases to break down foreign substances such as pesticides and
compounds naturally
found in plants,
known as phytochemicals.
But in 2013, researchers
found that a
compound in the plants,
known as aristolochic acid, seems to cause a specific DNA mutation.
No link has been
found between autism spectrum disorders (ASD) and a mercury - containing
compound known as thiomersal that is used in some vaccines.
There have only been seven
known enzymes associated with Dehalococcoides
found to have confirmed function on chlorinated
compounds.
These encouraging preclinical results suggest the
compound,
known as GS - 5734, should be further developed as a potential treatment, according to research
findings to be presented tomorrow at the IDWeek conference.
«It'd be good to
know, when these
compounds are mixed with other
compounds found in pesticides [such as fungicides], how that affects the efficiency of these P450 enzymes to detoxify neonicotinoids.»
The researchers also screened more than 100 anticancer
compounds to see whether they killed lab - grown cancer cells from the devils and
found that both strains responded to inhibitors of proteins
known as receptor tyrosine kinases.
«For example, you could figure out patterns of toxicity of potential new drug
compounds by looking at cellular responses and
finding common responses to other
known toxic molecules.»
We combined our
compound SH11037 with a
known antibody that works very similarly to the existing anti-VEGF drugs and
found that we could use doses of the two drugs.
These peptides interact with the same nucleobases
found in DNA, but each nucleobase is bound to an organic
compound known as a thioester.
The
findings indicate that
compounds known as positive allosteric modulators, or PAMS, can increase the natural pain - relief chemicals produced by the body in response to injury.
But the most precious nutrient
found in garlic is called allicin and is
known to be an extremely efficient antioxidant that destroys free radicals faster than any other similar
compound.
A Japanese study
found that an aromatic
compound in red raspberries was able to prevent and improve obesity in animal subjects; additional research on the effect is needed, but we
know enough to conclude that a handful of fresh raspberries sounds like an excellent summer snack.
From their previous studies, the researchers
knew that some foods worked better than others to neutralize garlic breath, and they theorized that two separate factors are responsible: Phenolic
compounds, which are antioxidants
found in fruits and vegetables; and enzymes, which are proteins that help speed up chemical reactions.
It's important to
know that although THC and CBD are the most studied components of cannabis, there are many more chemical
compounds found within the plant, such as cannabigerol (CBG), cannabichromene (CBC), cannabidivarin (CBDV), tetrahydrocannabivarin (THCV), terpenes, and flavonoids.
Garlic supplements contain a special
compound which is
known as alliin, which has been
found to be an extremely potent and powerful antioxidant.
However, within the past decade, researchers have become increasingly interested in the medical benefits of another
compound found in both plants,
known as cannabidiol (CBD).
Found in herbs like goldenseal, barberry and Oregon grape root, the
compound known as berberine has been used in Chinese medicine for centuries to treat a variety of health conditions.
This
compound can also be
found in a less common form
known as D - alanine
One study
found that a
compound in Spanish black radish was
found to be effective in helping with detoxification of acetaminophen, otherwise
known as Paracetamol, which is hepatoxic.