Sentences with phrase «known gene clusters»

Four of these six regions are located in known gene clusters: the protocadherin alpha cluster, two olfactory receptor clusters and a recently identified human microRNA cluster (Figure 2).

Not exact matches

Researchers have known for decades that the glycophorin cluster of genes is highly variable, but it was not possible to show that this genetic variation was responsible for protecting people against severe malaria.

Genome sequencing revealed that the isolated B. pumilus contained three unique gene clusters for the production of antimicrobial peptide compounds known as bacteriocins.

These microbes essentially keep mug shots of dangerous viruses in their DNA, storing snippets of viral genes between certain repeated segments of their own genes in a natural biological process known as CRISPR, for clustered regularly interspaced short palindromic repeats.

Most analytical approaches to this problem are rather rudimentary and involve calculating simple correlations among the genes whose expression changes in response to a perturbation, clustering the genes by molecular or known functional class, and drawing crude inferences about mechanism on that basis.

Plant biologists have long known that clusters of genes can do related tasks.

In their new study, the researchers looked for gene clusters associated with calcium - binding motifs similar to those in known antibiotics such as daptomycin and friulimicin, which require calcium for their antimicrobial action.

This past year, scientists hijacked survival tactics of prokaryotes to deliver the technological biological blockbuster known as the CRISPR (clustered regularly interspaced palindromic repeats) Cas (CRISPR associated genes) system.

Clustered regularly interspaced short palindromic repeats, also known as CRISPR, evokes a sense of unease in many people, especially since the term has become synonymous to gene editing technology.

The human T cell receptor beta (TRB, previously known as TCRB) gene locus on chromosome 7 (7q34) includes 65 Vb (variable) gene segments, followed by two separate clusters of genes each containing a Db (diversity) gene, several Jb (joining) genes, and a Cb (constant) region spread over 685 kilobases.

Our analysis predicts that the latter participate in the same biological processes as the known genes in the corresponding clusters — thus providing a starting point to study the function of poorly characterized transcripts.

In addition to well - described genes, clusters often contain transcripts the function of which has not yet been associated with a specific biological process thus providing novel unexplored links to known molecular pathways.

A large number of both known and novel biosynthetic gene clusters were identified, indicating that P. mesoacidophila ATCC 31433 is an untapped resource for discovery of novel bioactive compounds.

Genes with high expression levels are clustered in genomic regions known as ridges.