Sentences with phrase «known gene transcripts»
The draft genome generated by the present study covered > 70 % of the whole genome and harbored > 87 % of the known gene transcripts, thereby constituting the most informative genome resource currently available for bay scallop.
http://www.jgenomics.com/ Not exact matches
Based on the transcript sequences, the researchers identified 1,437 new promoters — short DNA sequences where transcription begins — in or between genes, on top of the 1,730 promoters they knew of.
Researchers know that cells chop single genes into shorter pieces called exons, which they mix and match into one transcript for creating a protein.
Here, segments of RNA known as transcripts — derived from specific DNA genes — hold vital clues regarding health.
Single - cell differential gene expression analysis revealed a spectrum of known transcripts, including several linked to cytotoxic and costimulatory function that are expressed at higher levels in the TEMRA (effector memory T cells expressing CD45RA) subset, which is highly enriched for CD4 - CTLs, compared with CD4 + T cells in the central memory (TCM) and effector memory (TEM) subsets.
The Neurogenomiks research group, linked to the Achucarro Basque Centre for Neuroscience (EHUgroup) and the University of the Basque Country (UPV / EHU), has just had a research article published in the scientific publication Journal of Immunology; it details how they have managed to show that the gene known as ANKRD55 produces 3 different transcripts of the messenger RNA, and that the genetic variant associated with MS greatly increases the production of these transcripts.
About 30 % of these putative genes have known protein domains and 80 % lie within transcripts predicted in silico.
Our analysis predicts that the latter participate in the same biological processes as the known genes in the corresponding clusters — thus providing a starting point to study the function of poorly characterized transcripts.
In addition to well - described genes, clusters often contain transcripts the function of which has not yet been associated with a specific biological process thus providing novel unexplored links to known molecular pathways.
Additional upregulated signal transduction related genes encoded proteins polycystin - 1L1, MLP and LIM regulatory proteins, fibrillins or related proteins containing Ca2 + - binding EGF - like domains, Ca2 + / Mg2 + - permeable cation channel, and other differentially expressed putative transcripts that may play a role in cellular signaling, including known extracellular proteins c - type lectin and collagen (see electronic supplementary material, table S5).