«Opiate use is
a known hepatitis C risk factor, and all people with a history of opiate use and substance abuse should be screened for hepatitis C,» Bernstein said.
On November 21st, a relatively small biotech company named Gilead Sciences (GILD) made headline news in the pharmaceutical investment community when it acquired a little -
known hepatitis C drug developer named Pharmasset Inc. (VRUS), for $ 10.8 billion, in an all - cash deal.
Not exact matches
Gilead Sciences is
known for its flagship
hepatitis C and HIV / AIDS drug franchises.
Her $ 5 billion TIAA - CREF Growth & Income Fund bought the stock in 2011, the day after Gilead acquired Pharmasset, a little -
known maker of
hepatitis C drugs.
And as we now
know, chronic inflammation can cause a host diseases and debilitating conditions, including rheumatoid arthritis, heart disease, digestive disorders (from IBD and IBS to Ulcerative colitis and Crohn's disease), asthma, ulcers, sinusitis, atherosclerosis, periodontitis, hay fever, active
hepatitis, diabetes, Alzheimer's and even cancer.
The problem with the targeted strategy is that not everyone
knows that they are at risk or that they have a chronic
hepatitis B infection.
If you do not have
Hepatitis B - you will typically
know by the time your baby is born if you do due to pregnancy screening - your baby has the same likely hood of getting
hepatitis B as he or she has of getting AIDS.
Theoretically they could infest the water leaching out of the dump with bacteria and viruses (polio,
hepatitis, dysentery), though that has never been
known to happen.
The virus can stay dormant for a long period of time and this is
known as chronic
hepatitis B. And if you test positive for
hepatitis B in pregnancy, don't worry, there're ways to protect your baby.
When the doctors or midwives conducting the delivery
know that the mother has
hepatitis B, they take all the preventive measures to minimize the risk of transmission.
We
know that HIV can be transmitted through breast milk, and there is a very small possibility that
hepatitis can be passed along if a woman has cracked nipples (although the risk is so low that experts say that mothers with
hepatitis are encouraged to continue breastfeeding).
He said, «Why should we be busy amassing wealth, beautiful houses, and acquiring exotic cars when there are millions out there who do not
know they are having viral
hepatitis in their system?»
Many Cuban accomplishments of this sector are well
known; for example Cuba produces widely used vaccines for diseases such as meningitis B and
hepatitis B, among others.
«
No matter how uncomfortable syringe service programs make us, they are proven to save lives, both by preventing the spread of diseases like HIV and
hepatitis C, and by connecting people to treatment that can put them on a path to recovery,» he wrote.
They found that
hepatitis in these «human hepatocyte chimeric mice» was caused by white blood cells
known as cytotoxic T lymphocytes (CTLs) that were specifically targeted to
hepatitis B virus.
Gene therapist Mark Kay and his postdoctoral student Anton McCaffrey, both of Stanford University in California, and their colleagues wanted to
know whether RNAi could target the virus behind
hepatitis directly — the only way to ultimately cure people of the disease.
Taylor's team of researchers examined Medicaid policies for
hepatitis C virus treatment using sofosbuvir, more commonly
known as Solvadi, and found that most should change policy to improve access to the treatment.
«It is not unusual for patients with
hepatitis C to come in and they have liver cancer, and they didn't even
know that they had cirrhosis that led to their cancer.»
I didn't
know it, but I had malaria and
hepatitis at the same time.
«Many young people who are at risk for
hepatitis C may acquire the infection and then not
know it, and then through drug injection practices may transmit it to others,» said Brandon Marshall, associate professor of epidemiology in the Brown University School of Public Health and corresponding author of the new study in the Journal of Adolescent Health.
Vaccines made of protein or sugar fragments, also
known as subunit vaccines, have been successful against a few diseases, such as
hepatitis and diphtheria.
«In people chronically infected with
hepatitis B or C, human papillomaviruses or other viruses
known to cause cancer, radioimmunotherapy could potentially eliminate virus - infected cells before they're able to transform into cancer cells.»
One of the most common causes of
hepatitis A (formerly
known as infectious
hepatitis) is a
hepatitis C virus infection in the liver.
«There are many people who don't
know that they have the infection, don't have access to
hepatitis C care and medications, and who haven't been treated.
«The new regimens will be game changers in the treatment of chronic
hepatitis C,» said senior author Vincent Lo Re III, MD, MSCE, assistant professor of Medicine and Epidemiology in the division of Infectious Diseases and department of Biostatistics and Epidemiology at Penn. «Given the high prevalence of this infection, particularly in baby boomers who didn't
know they were infected, having new, highly - effective treatment options to eradicate the virus will be a tremendous benefit to patients that will ultimately help us to reduce liver - related complications and re-infection rates.»
Some 1.8 percent of the U.S. adult population are infected with the
hepatitis C virus, most without
knowing it
Nearly 170 million people worldwide have
hepatitis C infections and one quarter of those cases can lead to liver disease that leaves the organ scarred and otherwise damaged, he says, adding, «The latest estimate is that in the U.S. five million people have
hepatitis C infections and many people don't even
know it.»
In 2001, Yasuhito Tanaka, now at Nagoya University, spent a year in the NIH laboratory of Harvey Alter, the virologist largely credited with the discovery of
hepatitis C. Tanaka wanted to
know when
hepatitis C entered the U.S., so he asked Seeff for viral samples to sequence.
The medications had harsh side effects and worked only for those patients with a particular genetic variant of the virus
known as genotype 1, which is the most common type in the U.S. and Canada but rare in many other countries with
hepatitis C epidemics.
«People just don't
know the various ways they might be able to acquire
hepatitis C, and that's really the point of just testing everyone in that [baby boomer] birth cohort,» Smith says.
But very little is
known about its role in infectious diseases, such as the notorious RNA viruses
hepatitis, influenza and the common cold.
Telomere dysfunction — alterations in the structure and / or functioning of telomeres — is one of the molecular mechanisms underlying a number of age - related diseases but, to date, little is
known about its possible role in pathologies of the liver such as cirrhosis,
hepatitis and liver cancer.
The data suggest that the SARS virus's closest
known, although still relatively distant, relatives are a mouse
hepatitis virus and a virus that causes bronchitis in turkeys.
Scientists already
knew that bacteria could contaminate utensils in this way, but the new study is the first to look at
hepatitis A virus and norovirus, the most common cause of foodborne illness in the United States.
«From a clinical standpoint, we've long
known about the devastating health impacts that chronic
hepatitis C has on a patient,» said Zobair Younossi, MD, chairman of the department of medicine at Inova and lead researcher on the study.
On the basis of the current studies as well as previous reports on the use of intradermal immunization against influenza,
hepatitis B, rabies, and other infectious diseases, 2,3,8 it is becoming clear that use of the intradermal route may at least partially overcome the relatively poor influenza - specific immune responses seen in certain at - risk populations, particularly the elderly, in whom the immune response in general is
known to diminish with age.9 Moreover, in times of shortage, the dose - sparing intradermal approach might be particularly well suited to the young, healthy persons included in the CDC's high - priority group for vaccination, such as health care workers, as well as to younger, otherwise healthy populations in general.
Second, the clinical presentation of pneumonia and
hepatitis is consistent with the
known spectrum of disease associated with adenoviral infections.
• Patients must have adequate coagulation (international normalized ratio (INR) or prothrombin time (PT), partial thromboplastin time (PTT) ≤ 1.5 times ULN) • Adequate liver function (total bilirubin ≤ 1.5 times the ULN, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ≤ 2.5 times ULN Exclusion Criteria: • Presence of active / uncontrolled central nervous system involvement • History of clinically significant cardiac disease; uncontrolled hypertension • Left ventricular ejection fraction (LVEF) < 45 % • Allogeneic stem cell transplant within 100 days before first dose of study drug •
Known history of human immunodeficiency virus (HIV) infection • Chronic or active
hepatitis B or C, requiring antiviral therapy • Evidence of history of bleeding disorder, dialysis, or coexisting cancer that is distinct in primary site or histology from the cancer evaluated in this study • Serious, uncontrolled infection • Unresolved chronic toxicity > grade 1 from prior therapy • Use of strong CYP3A4 inhibitors or strong inducers within 7 days prior to the start of study treatment and for the duration of the study
BPRC applies molecular, biochemical and immunological
know - how to provide new vaccine and therapeutic strategies for malaria, tuberculosis, HIV,
hepatitis C and other infectious diseases.
Many people do not
know that they have
hepatitis C until they already have liver damage.
As our aim was to indicate general tissue specific carcinogenic properties, we used all the
known subtypes of these cancers, including (1) hyper mutated and non-hypermutated colon cancers; (2) lung adenocarcinomas, large cell carcinomas, and squamous cell carcinomas (3) HER2 positive, basal, luminal A and luminal B breast cancers; and (4)
hepatitis B or
hepatitis C, cirrhosis or other agent causing hepatocellular carcinoma data.
«We
know what we can do to reduce the disease burden of
hepatitis C, but we're not even close to making an impact just because of it costing so much money.»
The doctors treating the man who has chosen to remain anonymous, believe that this sudden appearance of
hepatitis was due to his over-consumption of energy drinks, which meant consuming relatively huge amounts of vitamin B3, which is also
known as niacin.
Some research has linked long term consumption to aflatoxins with risk for diseases like liver cancer and
hepatitis B. (2) This is not surprising since aflatoxin in one of the most carcinogenic substances
known to man.
Physalin is another compound that is
known to strengthen the liver and help prevent
hepatitis B and help fight off certain cancers like leukemia.
Over time, the liver can become inflamed as a result of repeated overconsumption of alcohol,
known as alcoholic
hepatitis.
This can cause the low - grade damage
known as nonalcoholic steatohepatitis (steato meaning fat and
hepatitis meaning liver inflammation).
This herb is
no better for the liver than senna, as it contains anthracene glycoside, a compound that can lead to
hepatitis and liver failure.
With nonalcoholic fatty liver disease (NAFLD) currently affecting over 80 million Americans — and newly diagnosed cases of
hepatitis C topping 30,000 a year — the news of a non-toxic natural therapy for liver disease is certainly nice to
know.
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