Sentences with phrase «known human variation»

While 9 of them fitted within known human variation, it was claimed that the oldest sequence, from the 60,000 year old Mungo 3 fossil, was distinct from those of recent humans, and cast doubt on the theory that modern humans had originated in Africa.

We identify 13.4 million variants, substantially increasing the set of known human variation.

Not exact matches

With variation, but in essential correspondence of members of the plot, it happened of course throughout the spreading human family in the centuries and years, perhaps even months or days, preceding; and it has most assuredly continued to happen, in its significant essence, with persistence and always accompanying human carnage down to our own time and decade and, who knows, even day and hour.

Although researchers do not yet know the biological significance of these discoveries, they say that fully cataloguing the genome may help them understand how genetic variations affect the risk of contracting diseases such as cancer as well as how humans grow from a single - celled embryo into an adult.

Variation in pigmentation among human populations may reflect local adaptation to regional light environments, because dark skin is more photoprotective, whereas pale skin aids the production of vitamin D. Although genes associated with skin pigmentation have been identified in European populations, little is known about the genetic basis of skin pigmentation in Africans.

The study (which also involved a colleague) may sound simple, if a little gross, but variation in intestinal microbes, known as human microbiota, is highly complex.

And the variation in skull size and facial shape is no greater than in other species, including both modern humans or chimps, says Ponce de León — especially when the growth of the jaw and face over a lifetime are considered.

Whether the loss of mass by the glaciers is due to natural variation or is caused by human - influenced warming of the oceans is not known for sure.

Human traits like hair distribution, fatness and fat distribution, blood chemistry, and ear form are known to be affected by variation in dozens or hundreds of genes.

The mitochondrial genome of healthy humans also exhibits some natural variation — a single component of the mitochondrial DNA sometimes differs between one human and another — this is known as a SNP (single nucleotide polymorphism, «snip»).

But Dr. David Goldstein, director of Duke University's Center for Human Genome Variation, says, «Right now we know very, very little of the genetics of the diseases that most people will get.»

«Genetic recombination is a fundamental process, at the core of reproduction and evolution,» said study author Graham Coop, PhD, post-doctoral fellow in the Department of Human Genetics at the University of Chicago, «yet we know very little about where it occurs or why there is so much variation among individuals in this important process.»

We know, of course, that noncoding portions of the human genome contain functional elements contributing to phenotypic variation.

Taken together, these studies both highlight a fact that I find myself repeating many times: a significant fraction of functional variation in the human genome lies outside the exons of known protein - coding genes.

He is best known for his discovery that copy - number variation — a state in which cells have an abnormal number of DNA sections, sometimes associated with susceptibility or resistance to disease — is widespread and significant in the human genome.

If you remember, there were three different races to choose from in addition to three separate classes and genders, each variation making up a unique name for your choice (example: a male android Ranger was known as a RAcast; a female human Ranger was a RAmarl).

known for his synthesis of wit and formalism, reinventing the vocabulary of sculpture and turning it on its head, wurm works with the corporal silhouette in the same manner as a traditional sculptor, yet severely deconstructs and distorts each element of human likeness, mutating the body in unexpected and unconventional variations to further its ambiguity.

That said, human - induced climate changes there, and elsewhere, will, over the coming decades, reach the amplitude of known past and natural persistent variations, if the models are correct.

The team ran a suite of 400 computer simulations incorporating both what is known about how the climate could react to a greenhouse - gas buildup and a wide range of variations in the global economy and other human factors that might affect the outcome.

We now know that to be false — not because of the natural long - term variations in climate (to which you refer and which water planners could safely ignore), but to new, short - term dramatic changes that result from human - induced climate change.

If the answer is no, the next question is whether or not human activity can meaningfully avert this change outside of the normal variation.

The problem with this whole approach is that they still have this idea that natural variation is a small «error» ontop of a huge known, and not that natural variation is almost all the signal of which a small part ought to be human induced, but you really can't tell because the noise dominates the signal.