Sentences with phrase «known mechanisms of resistance»

Adds Tsvetkov: «We know a mechanism of resistance now.

Not exact matches

The mechanism of resistance in this variety was found to be antibiosis, and the level of resistance was found to be equal to that of the most resistant sources known to sorghum breeders in the world.

Although the general mechanism of resistance has been known for some time, exactly how M2 functions was less clear.

Researchers at the San Diego Supercomputer Center (SDSC) and the Moores Cancer Center at the University of California, San Diego, have described for the first time the molecular mechanism of cancer development caused by well - known «resistance» mutations in the gene called epidermal growth factor receptor (EGFR).

«Now, because we know the resistance mechanism, we can design elements to minimize the emergence of resistance as these promising new drug candidates are developed,» said Ben Shen, a TSRI professor who led the study, which was published February 20, 2014 online ahead of print by the Cell Press journal Chemistry & Biology.

«Knowing how these bacteria protect themselves, what the mechanisms of self - resistance of the bacteria are, is important because they could transfer that resistance to other bacteria,» said Tingting Huang, a research associate in the Shen laboratory who was first author of the study with Ryan M. Peterson of the University of Wisconsin, Madison.

The research, led by the University of Southampton and UCL, which took place on Mount Everest, assessed the mechanisms by which low oxygen levels in the body — known as hypoxia — are associated with the development of insulin resistance.

The role of gene regulation in C. auris drug resistance mechanisms and host interactions — such as overexpression of ERG11 and other known fluconazole resistance genes — are currently unknown.

Many mechanisms of MDR have been described, such as the overexpression of MDR1 (also known as P - glycoprotein or ABCB1) or other ATP - dependent transporters that pump drugs out of the cancer cells, amplification of drug - inactivating enzymes, mutations or modifications of drug targets, alterations in DNA repair machinery, and increased resistance to apoptosis (1 — 3).

Although that study didn't specify the disease mechanism at play, it's a well - known fact that excessive grain consumption leads to insulin resistance — sooner or later — and that insulin resistance is the primary underlying factor of most chronic disease, including cancer.

So we know if they're overweight, part of what's driving that metabolically is the mechanism of insulin resistance and inflammation.

So personally, if I already had the disease, and wanted to clean out and retool the cellular machinery as efficiently as possible, I would choose less saturated fat rather than more and leave out the oil, again based on what we know of the mechanisms of saturated fat induced insulin resistance.

On the commercial side, NAR is letting lawmakers know that proposals to curb 1031 exchanges will also meet with strong resistance, because the tax deferral mechanism is one of the main drivers of commercial real estate development today.