Metabarcoding works by comparing short genetic sequence «markers» from unidentified biological specimens to libraries of
known reference sequences.
Not exact matches
Kary Mullis [winner of the 1993 Nobel Prize for DNA
sequencing, and well
known for his unconventional scientific views] said in an interview that he went looking for a
reference substantiating that HIV causes AIDS and discovered, «There is no such document.»
In response, Page and colleagues devised what is
known as SHIMS (single - haplotype iterative mapping and
sequencing) to establish a definitive
reference DNA
sequence of the Y chromosome.
Reference materials are critical to properly evaluate the next - generation of gene
sequencing and genetic testing methods that will increase the reliability and effectiveness of precision medicine (also
known as «personalized medicine»), in which a person's genetic profile is used to create treatments and therapies unique to that individual.
From the test
sequence data, my colleagues and I
knew that the specimens were «complex» enough to obtain the full genome, but the only way to put the code together would be by using the genome of the band - tailed pigeon as a
reference map.
The alignment was performed using BLAT41 («− fine − maxGap = 3» for maximum sensitivity) using the
known plasmid as the
reference sequence.
The distance between Mezmaiskaya and a particular modern human
sequence known as the
reference sequence (Anderson et al. 1981) was 22, compared to 27 for the first Neandertal.
It's hard to
know which is more clever, the stripper's bare corpse in stiletto boots (one of the camera's favorite
reference points) or the
sequence in which her hacked - up body parts are wrapped in plastic and buried in a desert grave.
Instead, this is one of the many pieces of concept art from production designer Ralph Eggleston that allows more detailed planning of
sequences and shots and provides a frame of
reference for animators to
know what they're going to be creating.
The linear attribute indicates whether the
referenced item contains content that contributes to the primary reading order and has to be read sequentially («yes») or auxiliary content that enhances or augments the primary content and can be accessed out of
sequence («
no»).
SNPs were selected for each region based on
known polymorphisms between the Boxer
reference sequence and other breeds.