Sentences with phrase «known synergistic effects»

But you will only get the 5 strategies that have the greatest known synergistic effects on student learning.

Not exact matches

One group of chemicals, known as synergistic chemicals, makes it hard to accurately calculate chemical effects.

«One of the greatest uncertainties in EU environmental legislation is that we do not know the precise effects of synergistic chemicals when determining the scale of damage to nature from chemical cocktails,» says environmental chemistry professor and lead researcher, Nina Cedergreen.

This is in accordance with previous reports that decitabine and 5 - azacytidine produce a marked synergistic effect in combination with suberoylanilide hydroxamic acid and romidepsin in T - lymphoma cell lines by modulating cell cycle arrest and apoptosis.26, 27 As a mechanism of action, KMT2D mutations of B - lymphoma cells promote malignant outgrowth by perturbing methylation of H3K4 that affect the JAK - STAT, Toll - like receptor, or B - cell receptor pathway.28, 29 Here our study indicated that dual treatment with chidamide and decitabine enhanced the interaction of KMT2D with the transcription factor PU.1, thereby inactivating the H3K4me - associated signaling pathway MAPK, which is constitutively activated in T - cell lymphoma.13, 30,31 The transcription factor PU.1 is involved in the development of all hematopoietic lineages32 and regulates lymphoid cell growth and transformation.33 Aberrant PU.1 expression promotes acute myeloid leukemia and is related to the pathogenesis of multiple myeloma via the MAPK pathway.34, 35 On the other hand, PU.1 is also shown to interact with chromatin remodeler and DNA methyltransferease to control hematopoiesis and suppress leukemia.36 Our data thus suggested that the combined action of chidamide and decitabine may interfere with the differentiation and / or viability of PTCL - NOS through a PU.1 - dependent gene expression program.

It's possible to mix different types of nootropics, also known as «stacking», which results in a potent synergistic effect where the different components of the entire stack cause a greater effect than the sum of each nootropic's individual effects.

In one representative country, chronic pain takes up one - fifth of the entire health care expenditure, whereas in another it is three times as costly as all types of cancer together.59 One strategy which remains unexplored and could yield important insights is to combine a ketogenic diet with a known hypoalgesic pharmacological agent (e.g. amitriptyline) and note additive or synergistic effects, as have been noted for seizure control but only for some drugs.60

Many environmental contaminants have a synergistic effect as well; non-carcinogenic chemicals are known to turn to cancer - promoting carcinogens when combined.

Cistyase, for a healthy urinary tract Food supplement with Cranberry and plant extracts — 30 capsules • Synergistic action of plant extracts known for their beneficial properties on the urinary track and bioflavonoids from grapefruit seeds with antioxidant effects.

I know plant - based foods can be filling due to their fiber, but this natural pairing creates a wonderful synergistic health effect in order to rid your body of toxins that were produced during the workout while at the same time building your muscle better than it was before.