Sentences with phrase «known targets of»

To examine the functional role of Smad1 and Smad5 in GDF5 - induced neurite length, primary cultures were transfected by microporation with siRNAs targeting the co-Smad4 (required for nuclear translocation of Smad1 / 5 transcriptional complex [33]-RRB- or the Smad1 and Smad5 effectors proteins, which are known targets of miR - 181a (Table 2).

The «hotspots» of these trans associations, when grouped by pathway, highlight known targets of dysregulation in breast cancer such as ERBB2 and MYC.

Assume you are no the target of their actions.

We all know the target of adult dating, to find someone who is looking for some casual sex in your town or city.

First, we have to know the targets of our Playroom Organization Design.

Not exact matches

Recorded Future, a cybersecurity firm, published an analysis Tuesday laying out evidence that North Korean hackers — the same group, known as Lazarus, blamed for the infamous hack of Sony Pictures Entertainment in 2014 — were systematically targeting and plundering South Korean cryptocurrency exchanges.

«While some content marketers might assume they know what's of value to the target audience, the best way to identify the best opportunities is to do market research before any content is created.

Cornell knows the plight of retailers that can't adapt, and he's the first to acknowledge that Target has a lot of work ahead.

However, if your prospect list targets a limited range of contacts, the caller will know something specific about whom he or she is speaking with, thus making it easier to establish rapport and authority.

Social networks know a lot about consumer interests and demographics, so even though there are hundreds of millions of fans, marketers can accurately target the right people with the right message.

If Target can predict a pregnant woman's due date based solely on her buying habits at its stores (and it can), then just imagine how intimately Google — with access to your e-mail, calendar, address book and list of friends and acquaintances — could know you already.

Known as a «225 Action,» the Delaware filing would allow the current board, including the five targeted directors, to remain in place temporarily but would also bar the board from making any moves outside the normal course of business.

Your target market is made up of individuals just like me, and what they want to know is: «Do you even care about me?»

Although OPEC and allies have never officially targeted any specific price of oil with the production cut agreement, each member of the pact knows very well where they want oil prices to be in order to balance their budgets that have been stretched thin in the price plunge.

The model of many a successful small firm is one «get - up - and - go» individual with an entrepreneurial flair who has identified a market they would like to get involved with; and one other individual who may be less entrepreneurial in spirit but knows the target market well.

She's got a clear concept of what she wants her brand to be and she knows her target market.

Of course no matter if it is NGDP targeting, the Taylor rule, or even a rule that would have the Fed tie itself to gold - the entire debate about rules - based monetary policy ignores the obvious: rules are meant to be broken.

The grand opening of Target Canada was set to begin in one month, and Tony Fisher needed to know whether the company was actually ready.

However, it's still important to select a target time frame in the letter of intent and outline any known provisions, such as: whether it will happen over time (a progressive close), whether there will be an escrow period, or if everything is expected to happen on a single day (a sign and close).

You already know they are interested in spending money with you and chances are they are your target demographic (or part of a new emerging target demographic).

The Bank of Canada's 2 % inflation target may no longer make sense.

Right now I'm using my blog as a «Get to Know Me» type of free service to really build up a strong presence before offering up targeted services & products.

Moss points to a number of options, including targeted communications that let them know that management is aware of their concerns.

Sticking to a prescribed format, requiring that the updates be concise and on target and knowing when to move a discussion outside of the regular meeting is important to making sure the meetings maintain effectiveness.

A few of the well - known companies are Target, Google and Dell, and the common thread found in all of the companies was that they had a specific group, or person, dedicated to solely doing social media.

Here's what we do know about the state of Afghan security forces: A September report from the Special Inspector General for Afghanistan Reconstruction indicated that ANDSF is nowhere near its 352,000 target personnel level: Afghan National Army force strength, in particular, fell from 185,817 in September 2013 to 168,327 in November 2016, thanks to increasing attrition rates and fluctuating readiness.

«And then we have a legal review that says that engaging this target comports with the laws of armed conflict and that engaging in these circumstances is permissible according to those laws, and once we've established all of those things we go to the government of Iraq and ask them for permission to strike that building, and they'll say yes or no, and they do say both, depending on the structure.

Like them, Charney has built a powerful brand known in many parts of the world, which is why American Apparel is an attractive acquisition target in its weakened state.

In fact, it supplies you with a mountain of data that will tell you everything you need to know about buying trends, customer demographics, peak hours, and whatever else you need to optimize your sales targeting.

But looking through resume books, consulting alumni networks and generally poking around to know which students make the most attractive targets for recruitment is only the very beginning of APT's efforts:

We don't know whether the officials targeted in the «anti-corruption» campaigns were really unusually corrupt, lascivious, or treacherous — or whether they were just political opponents of Xi.

We don't know where those people are; Rural counties are incentivized to overreport population to receive more benefits from higher levels of government, while city districts report lower figures to hit population control targets.

«No one, not even the North Koreans, knows the CEP of the HS - 12,» Mike Elleman, the senior fellow for missile defense at the International Institute for Strategic Studies, told Business Insider, referring to circular error probable, or the distance by which a missile can be expected to miss its target.

«When clients get bored of the advertisements you've created, you know when it's starting to sink in with your target market,» she says.

What isn't often talked about, however, is that one of the best ways to get to know your target audience isn't just by using Google Analytics or some other type of software.

At first, the platform will target individuals who are experiencing well - known health conditions, such as knee surgery, following them throughout the regimen of pre-op, post-op, and maintenance.

Identify the values of the target group and make sure prospective employees know how the company lives them.

Islamic State's offshoot in Afghanistan, known as the Sunni jihadist group's so - called Khorasan Province, is suspected of carrying out several attacks on minority Shi'ite Muslim targets.

Everyone knew Target was struggling with its supply chains, but we never knew the full extent of the chaos until now

Once they knew it was safe to leave their homes, they went to relatives, coffee shops and even a Target to take advantage of available electricity and WiFi.

State officials have been targeted with withering criticism for the website, known as Cover Oregon, which never launched because of technical problems.

And what I know for sure is that it's much easier to hit a target when one is in front of you.

However, even if they're not fans but you know they are inside your exact, ideal target audience, then you can still create high - value content and amplify that content into the news feed of those folks!

Desperate for some kind - any kind - of retail store in which to spend their money up in the frozen, polar - bear - infested land known as «Canada,» shoppers flocked to recently opened Target stores across the country, giving the U.S. retailer 86 million of their «loonies.»

For instance, an initiative known as «should - cost» has effectively driven down the high price of many programs by requiring managers to determine what a given program or piece of a program should cost and then set targets for fitting the program into its cost paradigm.

A number of high priority targets with strong potential for discovery were identified, including at least 30 known gossan outcrops with similarities to the original gossans above the known lodes at Bawdwin and at least 30 shallow historical mine adits outside the known mine area, with several containing substantial base metal sulphide intersections.

And he also knew that the business he's starting, a service called Diggen to allow Web retailers to better target shoppers, was hardly about to inflame the passions of the kinds of people who donate money on sites like Kickstarter.

Once you know who you want to target, the next step is talking to the company or its representative and convincing them of your product's potential.

The anti-abortion targeting effort relies on a feature of ad networks known as geofencing.

Each radio station delivers a very specific audience, so once you know the age and gender of your target customers, you can zoom in on stations that serve those people.