Sentences with phrase «kynurenine into»
It turns out that activation of the PGC - 1a1 pathway increases skeletal muscle expression of kynurenine aminotransferases, to enhance the conversion of kynurenine into kynurenic acid.
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KATs convert a substance formed during stress (kynurenine) into kynurenic acid, a substance that is not able to pass from the blood to the brain.
Also, it seems that in the presence of inflammation, tryptophan is not metabolized into serotonin but instead kynurenine and eventually the excitotoxin quinolonic acid, contributing to unoexcitoxicity and neuronal degeneration.