Sentences with phrase «lab animal studies»

While little data about toxicity exists, lab animal studies have shown toxicity to the nervous system and liver at high doses.

More than 6,000 papers have been published on these so - called beta glucans, but almost all the data about preventing infections had come from petri dish or lab animal studies, until a few years ago when a series of experiments on athletes showed beneficial effects — but that was in marathon runners.

In lab animal studies, we aim to reduce variability between groups by housing all of the animals in the same room, using the same number of animals per cage and using the same water, bedding, enrichment and diet.

Not exact matches

A number of lab and animal studies have found that healthy organic food may increase antioxidant content, helping to protect cells from damage.

They say a new study found that, when exposed to heat, baby bottles release a chemical that, researchers say, has been linked to obesity, diabetes and developmental problems in lab animals.

Pairing state - of - the - art technology like DNA sequencers and robotic fluid handlers in the lab with Shedd's world - class animal expertise, the lab enables Aquarium researchers to study the countless invisible organisms that co-exist with the 32,000 animals in Shedd's care.

All of these toxicological statistics are derived from studies wherein the targets (almost always lab animals) did not receive decontamination or treatment for their injuries.

By studying human cancer cells and animal models of cancer in the lab, our researchers have shown that loss of PTEN leads to high levels of PI (3,4) P2, which could result in hyperactivation of AKT.

In the Eickbush lab, he began a study of the evolutionary relationships among non-long-terminal-repeat (non-LTR) retrotransposons, which are abundant in the genomes of animals, plants, and fungi.

In addition, formaldehyde has been linked to reproductive problems, including miscarriages, in some studies of industrial workers and lab animals.

The research is part of a growing field called ecoimmunology, which aims to push the study of immunology beyond lab animals like fruit flies and mice and understand how immune systems function in real - world settings outside the lab.

For example, animal studies have shown that neurons derived in the lab from human embryonic stem cells improve Parkinson's symptoms; however, any residual stem cells associated with those neurons could form masses of unwanted cells.

Weiss says she used lab animals because they are well studied: «We know what they do or what they're supposed to do.»

Flu is hard to study in the lab because virtually no lab animals get it the way humans do.

The biomedical device company CryoLife, Inc. is now using the researchers» design to build ring implants for further studies in lab animals, Karp says.

The study — which looked at the action of Substance P within nerve cells in the lab and in animal models — focused on acute pain, but Professor Gamper aims to look at its role within chronic pain as well.

In earlier animal studies, the Andersen lab found that it is here, in the PPC, that the initial intent to make a movement is formed.

«We were very curious to see what would happen if we were to change the expression pattern of Pax6 in developing mouse brain to mimic that observed in large - brained animals,» says Fong Kuan Wong, a PhD student in the lab of Wieland Huttner and first author of the study.

Indeed, U.K. labs have reported 21 similar poliolike cases in cattle and sheep over the last 10 years, and samples from some of those animals are now being studied.

And although there's already «a battery of evidence» for laterality in animals from lab studies, Lesley Rogers of the University of New England in Armidale, Australia, says, «we're only beginning to look at how this laterality manifests itself in the wild.»

To better determine the role of specific chemoattractants in type III hypersensitivity, lead author Yoshishige Miyabe, MD, PhD, a research fellow in Luster's lab, used multiphoton intravital microscopy — an imaging technology pioneered for studies of immune cell movements in living animals by CIID investigator and co-author Thorsten Mempel, MD, PhD — to follow in real time the development of IC - induced arthritis in a mouse model of rheumatoid arthritis.

In addition, D4 causes tumors, reproductive problems, altered organ size and acts like a weak estrogen in studies of lab animals.

In addition to the cases in Louisiana, laboratory studies have linked atrazine to hormonally responsive cancers in humans and lab animals.

However, Laksari and Kurt emphasize that their findings are predictions that need to be tested more extensively in the lab, either with animal brains or human brains that have been donated for scientific study.

Studies with lab animals have linked pyrethroid exposure to damage of the thyroid, liver and nervous system, as well as impairment of behavioral development, changes in the immune system and disruption of reproductive hormones, according to the 2006 EPA review.

Recent studies in lab animals and humans show that the much - maligned material can be a source of cells useful for treating a wide range of ills.

«We might not have known urchins and six - armed sea stars were affected if lab - held animals hadn't died right in front of us,» said the study's lead author Laura Jurgens, a graduate student at UC Davis Bodega Marine Laboratory who earned her doctorate in May.

«In addition to being used in animal studies to help us understand how the brain works, this new endoscope might one day be useful for certain applications in people,» said Shay Ohayon, who developed the device as a postdoctoral researcher in James DiCarlo's lab at the Massachusetts Institute of Technology.

And among lab animals, rats are considered particularly relevant to human cancer studies because they need the same nutrients and proportion of protein for maximal growth as humans.

Complicating study of the virus even further, a lab study found that an infected mosquito can pass the virus to nearby mosquitoes while they are feeding on an uninfected animal.

The specimens come from a variety of animal species, including okapi, platypus, and sloth, and are embedded in paraffine wax as soon as they arrive to the lab, where scientists study them to help vets diagnose and treat eye diseases.

Prior studies from the Sancar lab showed that excision repair works more efficiently for actively transcribed genes in animals and bacteria.

A PETA study conducted earlier this year found that there has been a 73 % rise in the use of these animals in U.S. labs over the past 15 years, obviating the need for other types of animals.»

Today, the UNC School of Medicine lab of 2015 Nobel laureate Aziz Sancar, MD, PhD, has published an exquisite study of this powerful DNA repair system in plants, which closely resembles a repair system found in humans and other animals.

So instead of studying the whole animals, he began isolating single nerve cells from the mole rats and investigating them in lab dishes to track the molecular basis of the rodent's pain insensitivity.

The causes of such unpredictable results, Harris said, can include bad ingredients in the lab, including contaminated and misidentified cell lines; poor research design, including insufficient numbers of mice in animal studies; statistical error and overreach, including «HARKing» (hypothesizing after the results are known), a push beyond the limits of the data; and funding pressures, which can lead scientists to hype or exaggerate their results to remain competitive for additional grant money.

Those tests will answer basic questions about changes in cells and genes; they are not the elaborate, years - long studies exposing lab animals or examining humans that can answer most important health questions.

However, animals that had mutations with Pcdha9, but not Sap130, can display defects in the aorta, but with normal - sized left ventricles, suggesting interaction between the two genes is needed to cause all the features of HLHS,» said Xiaoqin Liu, M.D., Ph.D., the first author of the new study and a research instructor in Lo's lab.

For the current study, Jessica Childs, a graduate student in Kroener's lab, applied VNS to a test group of rats used in the study in a process called «extinction learning» to determine whether the procedure could help the animals learn different behaviors and reduce their drug cravings.

Researchers have grown vocal cord tissue in the lab, and it works — the tissue was able to produce sound when it was transplanted into intact voice boxes from animals, according to a new study.

In the lab, they adapted the standard experimental technique for studying place cells: implanting electrodes directly into a rat's hippocampus and recording from them as the animal runs freely in a large box (see «A sense of place»).

The spiders are comparable to mutant animals scientists create in the lab to study circadian rhythms this short.

But his lab's animal studies have revealed that asymmetry in an immature egg is important to the development of an embryo.

That active engagement included posting online endorsements from experienced scientists and others, providing compelling «lab notes» containing updates and project background, and offering donors a nonmonetary reward such as visits to the research lab and, in the case of wildlife studies, offering photographs of subject animals.

That worries Gardiner and Sandoval Guzmán because the animals that they study, like many lab animals, are highly inbred.

CONFUSION reigns among those studying animal minds, following the revelation that Harvard University has investigated alleged misconduct in the lab of one of the field's brightest stars.

But about 10 % of the agency's budget goes to its intramural program, which has over 1000 principal investigators (PIs), 4000 postdocs, hundreds of labs, animal facilities, and many clinical studies.

Researchers are still working to understand just how some of these pathways and hormones can influence disease risk, primarily through animal studies in the lab.

Almost every animal behavior studied in the lab, from the effectiveness of experimental drugs to the ability of monkeys to do math, is affected by stress, notes Paul Flecknell, a veterinary anesthesiologist at Newcastle University in the United Kingdom who researches ways to alleviate pain in animals.

Since then, he and his colleagues have shown in lab studies of rodents and pythons that these animals grow up bigger and faster when they eat cooked meat instead of raw meat — and that it takes less energy to digest cooked meat than raw meat.