But the low doses used in anti-aging research with mice and other
lab animals cause few side effects.
Not exact matches
«when run through a simulated dishwasher 50 to 75 times, name - brand baby bottles leach the chemical bisphenol A, or BPA, in levels that have
caused reproductive abnormalities in
lab animals...» This is one of the highest - volume produced chemicals in the world,» says Fredrick vom Saal, a Missouri biology professor and BPA researcher.
«Formaldehyde has been shown in both humans and
lab animals to
cause structural and numerical changes in their chromosomes, which are associated with increased cancer risk, particularly with leukemia.
In addition, D4
causes tumors, reproductive problems, altered organ size and acts like a weak estrogen in studies of
lab animals.
While trying to come up with a contagious method of birth control among rodent pests, an Australian
lab in 2001 modified a mousepox virus, which, unintentionally,
caused the rodents» immune system to fail completely — even in
animals previously vaccinated against mousepox.
One of the
causes of these failures can be found in the pre-clinical
lab, during testing with
animals.
The
causes of such unpredictable results, Harris said, can include bad ingredients in the
lab, including contaminated and misidentified cell lines; poor research design, including insufficient numbers of mice in
animal studies; statistical error and overreach, including «HARKing» (hypothesizing after the results are known), a push beyond the limits of the data; and funding pressures, which can lead scientists to hype or exaggerate their results to remain competitive for additional grant money.
Research on
lab animals has shown some of the chemicals
cause cancerous tumors and damage developing brain cells, and some can alter hormones essential to reproductive and neurological development.
However,
animals that had mutations with Pcdha9, but not Sap130, can display defects in the aorta, but with normal - sized left ventricles, suggesting interaction between the two genes is needed to
cause all the features of HLHS,» said Xiaoqin Liu, M.D., Ph.D., the first author of the new study and a research instructor in Lo's
lab.
Although researchers have known that nitrites and nitrates at high doses can
cause cancer in
lab animals, de la Monte's results suggest that long - term, low - dose exposure to the compounds may be linked to chronic diseases in humans.
But how closely does the stress
caused by restraining a
lab animal mimic that experienced by human patients?
English government
lab blamed for foot and mouth outbreak Leaky drainage pipes may have allowed the foot and mouth virus to escape from a
lab funded by England's Institute for
Animal Health in Pirbright,
causing last month's outbreaks at two farms in nearby Surrey, government investigators said.
They are covered with tiny cells bearing dangerous toxins that can paralyse prey
animals and
cause fatal heart attacks in
lab rats.
* Two small
lab vials of Yersinia pestis, the
cause of plague, is an acute bacterial infection transmitted to humans and some domestic
animals by fleas that come from infected rodents.
Lab studies,
animal studies, and observations of evacuated patients treated in Europe and the USA have suggested that Ebola might
cause lung damage by replicating itself in lung tissue.
Eight past studies looked at whether the sweetener
causes cancer in
lab animals, says veterinary pathologist James Swenberg of the University of North Carolina at Chapel Hill.
Our wet -
lab research is focused on the study of Brucella, a facultative intracellular bacterium that
causes brucellosis, one of the most common zoonotic diseases in the world in humans and a variety of
animal species.
His
lab develops isogenic human pluripotent stem cells and transgenic
animals to model disease, with the goal of delineating novel approaches to influence outcomes for Huntington disease (HD) and Fragile X Syndrome (FXS), the most common genetic
causes of dementia and intellectual disability, respectively.
George and colleagues trained
lab rats to self - administer and
caused some of the
animals to become dependent on alcohol.
This is a little different from the topic at hand, but the idea is pretty much the same: Do
lab animals actually find some people more calming, while others
cause them stress or fear?
Still, by the 1990s DuPont knew that the chemical
caused cancerous tumors in the testes, pancreases, and livers of
lab animals, and there was even evidence of human DNA damage and links to prostate cancer in workers exposed to PFOA.
Interestingly, while massive quantities of safrole
caused liver cancer in
lab animals, it seems that small doses may actually play a protective role for humans.
Paraffin fumes have been found to
cause tumors in the kidneys and liver of
lab animals.»
These chemicals have been shown to
cause cancer in
lab animals.
Princeton researchers also state: «In addition to
causing significant weight gain in
lab animals, long - term consumption of high - fructose corn syrup also led to abnormal increases in body fat, especially in the abdomen, and a rise in circulating blood fats called triglycerides».
It is prescribed for edema in Germany and may be safer than other remedies because it replenishes potassium.910 Preliminary
animal studies suggest that dandelion may help normalize blood sugar and fight inflammation.11 Dandelion root extract
caused cancer cells to destroy themselves in a Canadian
lab study, which prompted a clinical study (the results of which are not yet available).12
Acrylamide has been shown to
cause cancer in
lab animals, but we don't know what levels of acrylamide exposures are dangerous for humans.
This chemical was banned by the FDA long ago due to it
causing infertility and destroying the testicles of
lab animals.
Of course, some celebrities were in attendance to cheer on the
animals, help spotlight shelter dogs and support the
cause including Denise Richards, Kelly Wearstler, who adopted a
lab mix puppy, Autumn Reeser, Patrick Fabian, Amy Smart, Rachelle Lefevre, Matthew Allen, who fostered a cute white pit bull, and Julie Marie Berman.
Even with these omissions, this estimate is 100 - 1000 times higher than our estimates for the numbers of
animals affected by advocacy for companion or
lab animals, suggesting that farm
animal advocacy is the most important
cause of the three — at least in terms of the number of
animals involved.
Researchers in the Modiano
Lab, as part of the
Animal Cancer Care and Research Program, are working to understand what
causes cancer and what drives its behaviors — translating that knowledge into better treatments and, ultimately, fewer cases of cancer in
animals and in human patients.
This happens when a vaccine is injected into an
animal with a suppressed immune system (
caused by genetic factors, poor diet, stress, existing illness, etc.); or when the vaccine manufacturer fails to render the viral component of the vaccine harmless in the
lab.
While there is no clear evidence that they
cause cancer in humans, their various harmful effects in
lab animals were enough to prompt the Environmental Protection Agency to designate some 200 miles of the Hudson as a Superfund toxic site 25 years ago.