Not exact matches
For example, animal studies have shown that neurons derived in the
lab from human
embryonic stem cells improve Parkinson's symptoms; however, any residual
stem cells associated with those neurons could form masses of unwanted
cells.
The disease model, described in a new study by a UC San Francisco - led team, involves taking skin
cells from patients with the bone disease, reprogramming them in a
lab dish to their
embryonic state, and deriving
stem cells from them.
For the purpose of additional experiments, the researchers generated myocardial
cells from embryonic stem cells and human skin
cells, in collaboration with the
lab headed by Prof Dr Jürgen Hescheler at the University of Cologne.
By contrast,
embryonic stem cells are culled
from embryos created and frozen in fertility
labs.
The only previous trial using ES
cells to treat Parkinson's began last year in Australia; participants there received
stem cells from parthenogenetic embryos — unfertilized eggs that are triggered in the
lab to start
embryonic development.
The answer to this question comes
from the
lab of Marcel Leist (University of Konstanz, Germany) and their studies employing a defined and controllable in vitro system of post-mitotic murine astrocytes generated
from embryonic stem cells (mAGES)[1].
Scientists in the
lab have successfully generated neural
stem cells (NCS)
from human
embryonic stem cells and human induced pluripotent
stem cells (these are
stem cells that have been reprogrammed
from adult
cells).
Recently, his
lab used induced pluripotent
stem (iPS)
cells — adult
cells made to act like
embryonic stem cells — made
from skin
cells of patients carrying apoE4, or other mutations related to Alzheimer's, to study their effects on the development, survival, and degeneration of human neurons.
According to the National Institutes of Health, most
embryonic stem cells come
from eggs fertilized for in vitro treatments in a
lab, not
from eggs fertilized in a women's body.
Labs that derive new human
embryonic stem cell lines are few, partly because they can not get financial support
from federal sources.
The
lab, called the MStem
Cell Laboratories, derived
embryonic stem cells from the embryo, and coaxed them to grow into nerve
cells.
The
cells, derived
from iPS
cells, RPE
stem cells, or human
embryonic stem cells, are grown and differentiated in the
lab, then placed in a harmless fluid to be injected.
In a bid to harness the potential of
embryonic stem cells, surgeons in California have implanted
lab - grown retinal
cells into the eyes of two patients going blind
from macular degeneration.
Neural
stem cells are found in adult or fetal brain and spinal cord or derived
from embryonic stem cells, which have the capacity to become any
cell type in the body, or induced pluripotent
stem (iPS)
cells, tissue - specific
cells that are reprogrammed in the
lab to behave like
embryonic stem cells.
Although anti-abortion groups oppose
embryonic stem cell research because they believe it destroys unborn human life and that it threatens to expand that destruction as
stem cell research grows increasingly beneficial to humans already born and suffering
from disease and debilitation,
embryonic stem cells now are reproduced in
labs from cells derived years ago
from originals.