Sentences with phrase «lab mice by»

The method was successfully tested on lab mice by injecting the cellulose scaffolding under its skin.

A large - scale study of two strains of lab mouse by Viola André, Martin Hrabé de Angelis and co-authors shows that the inclusion of nesting material and shelters as environmental enrichment does not impair the scientific assessment of a battery of 164 physiological parameters in mice.

Not exact matches

It is dominated by the far - seeing genius of Josh Boger, who at age 7 does experiments in a lab above his parents» garage (including sending a hapless mouse soaring aloft on a Hindenberg - type contraption he rigs up).

Believe it or not, the ultra liberal look just as foolish (seriously: set the lab mice we are testing cancer treatments on free, but kill the unborn children because their mothers deserve not to have their lives ruined by stressful bundles of joy)

In a lab study, an extract of the leaves stopped the growth and progression of prostate cancer cells by up to 75 % in mice.

Another study published in 1999 by Anderson Laboratories found that lab mice exposed to various brands of disposable diapers experienced asthma - like symptoms, as well as eye, nose and throat irritation.

The researchers mimicked cosmic - radiation exposure by briefly bombarding the brains of lab mice with high - energy particles.

About a third of mice exposed to severe stress (in the form of aggressive attacks by other rodents) seem to breeze through these assaults without developing the social withdrawal, listlessness or other depression and traumalike symptoms displayed by most of their rodent lab - mates.

For decades, wildlife documentaries have promoted the idea that Komodo dragons owe their success as predators to toxic bacteria in their saliva — a claim bolstered by a 2002 study reporting deaths among lab mice injected with their saliva.

I have killed 261 lab mice, including one by accident.

The untold millions of mice, rats, and even dogs owned by pharmaceutical companies, biotech corporations, and other industry labs are off the table says Bellotti, noting the business interests of his more conservative allies.

For example, mice have been given an extra color vision gene in the lab, and it has been shown that the protein manufactured by that gene expands the scope of their vision by enhancing their ability to see longer - wavelength light without any other changes in the brain.

To mimic this obesogenic environment, the teams led by Mara Dierssen at CRG and Rafael Maldonado at UPF offered mice the option of a high - fat «cafeteria» diet or a mixture of chopped - up commercial chocolate bars alongside their regular lab chow, before carrying out a detailed analysis of the animals» activity and feeding behaviour.

The latest findings build on previous work by Dr. Habib's lab showing that the same combination of drugs was successful in a mouse model of glioblastoma, a deadly type of brain cancer.

Now, immunologists at the National Institute of Diabetes and Digestive and Kidney Diseases in Bethesda, Maryland, have contaminated lab mice in a different way: by giving them gut bacteria from wild mice.

The researchers tested that idea by infecting newborn mice (which developmentally resemble a human fetus) with different lab - made versions of Zika.

He and colleagues at the University of California, San Francisco, injected the brains of mice with prions they had created in the lab by misfolding normal prion protein, known as PrP.

Diamond's lab circumvented this problem by creating female mice that had a key interferon gene knocked out; in a second experiment, they treated pregnant animals with an anti-interferon antibody.

To better determine the role of specific chemoattractants in type III hypersensitivity, lead author Yoshishige Miyabe, MD, PhD, a research fellow in Luster's lab, used multiphoton intravital microscopy — an imaging technology pioneered for studies of immune cell movements in living animals by CIID investigator and co-author Thorsten Mempel, MD, PhD — to follow in real time the development of IC - induced arthritis in a mouse model of rheumatoid arthritis.

He has found that when a lab mouse misses its daily ration, B. theta consumes the globs of sugary mucus made every day by some cells in the intestinal lining.

In collaboration with Ding, the lab of Olivier Voinnet at the Swiss Federal Institute of Technology in Zurich also reported in an accompanying paper the detection of viral siRNAs in cultured mouse embryonic stem cells infected by the Encephalomyocarditis virus.

The tumors in Sand's lab might be explained by the high dose, the fact that the mice were newborns, and the type of mouse, suggests Kay, who was involved with a past clinical trial administering AAV to the liver to treat hemophilia.

Now, a preclinical study, from the lab of Olivier Berton, PhD, an assistant professor in the department of Psychiatry, in collaboration with Sheryl Beck, PhD, a professor in the department of Anesthesiology at Children's Hospital of Philadelphia, found that bullying and other social stresses triggered symptoms of depression in mice by activating GABA neurons, in a never - before - seen direct relationship between social stimuli and this neural circuitry.

To investigate the relationship between temperature and immune response, Iwasaki and an interdisciplinary team of Yale researchers spearheaded by Ellen Foxman, a postdoctoral fellow in Iwasaki's lab, examined the cells taken from the airways of mice.

Back in the lab, the ecologists counted up the attacks by different predators — they can tell the nick of a bird's beak from the teeth marks of a mouse or the paired piercings of ant, for example.

Earlier work by Morikawa's lab, also on mice, showed that repeated amphetamine use has a similar positive effect on reward - based conditioning.

They have since learned that as many as 40 of those lines may never be fully developed; some may even have been contaminated by mouse cells used to sustain them in the lab.

Reyes lab began by treating old dystrophic mice with direct injection of THI.

Studies of individual neurons in dishes of cultured neurons and in brain slices by co-first author Robert E. Stanley, a graduate student in the lab, revealed that neurons in the mutant mice had decreased numbers of dendritic spines, an important part of the synapses that neurons use to communicate with one another.

These findings were confirmed by two - photon imaging of neurons in the brains of living mice by the lab of collaborator Yi Zuo, PhD, a neuroscientist at UC Santa Cruz, as well as electrophysiological recordings from neurons in brain slices by the lab of collaborator Vikaas Sohal, MD, PhD, an associate professor of psychiatry at UCSF.

Prather's lab has previously engineered E. coli to produce glucaric acid by adding three genes — one each from yeast, mice, and a strain of bacteria called Pseudomonas syringae.

Spearheaded by co-lead authors Sinisa Hrvatin, a postdoctoral fellow in the Greenberg lab, Daniel Hochbaum, a postdoctoral fellow in the Sabatini lab and M. Aurel Nagy, an MD - PhD student in the Greenberg lab, the researchers first housed mice in complete darkness to quiet the visual cortex, the area of the brain that controls vision.

Yet a mouse study reported in May by Mark Kay's lab at the Stanford University School of Medicine delivered some sobering news about RNAi.

Last year, the Li lab published a paper in Journal of Clinical Investigation showing that CRISPR - Cas9 gene editing, delivered by viral vector, can reverse signs of HD in a mouse model.

This study, led by Garret D. Stuber, PhD, associate professor of psychiatry and cell biology & physiology, and Jenna A. McHenry, PhD, a postdoctoral research associate in Stuber's lab, identified a hormone - sensitive circuit in the brain that controls social motivation in female mice.

«By decreasing ROS levels within a chronic wound in a diabetic mouse model, my lab was able to normalize conditions and heal the wound,» Martins - Green said.

In working with mice, researcher Jeffrey Mogil, at McGill University's Pain Genetics Lab, has found that the response to pain can vary tremendously by breed and by gender.

Led by Rowitch lab postdoctoral fellow Anna Molofsky, MD, PhD, the researchers studied the spinal cord sensory motor circuit, which allows both mice and humans to react without thought — to jerk a limb away from something hot, for instance.

To determine how ESRP1 mutations cause hearing loss Alex Rohacek, a graduate student in the Epstein lab, evaluated embryos in which Esrp1 was deleted in a mouse model developed by the Carstens lab.

«The thing that's impressive is that morphological changes in the neurons that many labs have seen, both in fragile X patients as well as in mice that model fragile X, were reversed by changing the expression of this PAK gene.

The scientists confirmed that these mice have learning problems by testing them in a Morris water maze, a common lab test of animal learning and memory.

In a petri dish, Rowe and colleagues could tell that the bark scorpion venom works by targeting Nav1.7 in cells from lab mice and grasshopper mice.

A study by Stephen Abolins, Mark Viney and colleagues of the immune ecology of wild house mice — the same species as the lab mouse — shows that their immune state is promoted by individuals» body condition and constrained by their age.

Another lab ran into a similar problem when it tried to replicate work by Stanford stem cell biologist Irving Weissman and his colleagues, who reported in 2012 in the Proceedings of the National Academy of Sciences that an antibody to a tumor cell surface receptor called CD47 can slow tumor growth in mice.

Berkeley Lab researchers found that the sticky residue left behind by tobacco smoke led to changes in weight and blood cell count in mice.

During this BSA Lecture, Kevin Esvelt of Massachusetts Institute of Technology discusses his lab's work with communities on Nantucket and Martha's Vineyard to prevent tick - borne human illness by developing hereditary traits in mice that could immunize them, removing a vital link in the spread of Lyme disease.

To this aim we generated new conditional knockout mouse strains, which are currently analyzed to unravel the mechanism of a recently discovered unexpected protective role of TNFSF14 / LIGHT by our lab in an Inflammatory Bowel Disease (IBD)- like mouse model.

Cells from mice bred in Singh's lab to lack PU.1 allowed the researchers to manipulate the cells» decision - making machinery by introducing different amounts of PU.1.

The lab has shown that when NMDAR function is impaired by a genetic mutation, they can recreate, in the mouse, the structural, neurochemical, and functional alterations in the brain that are characteristic of schizophrenia — for example, cognitive and memory impairments for which there are currently no effective treatments.

From previous research on genetic instability, conducted by the Pearson lab and others, the researchers suspected that the dramatic difference between the mice might boil down to variances in one particular biological process, called mismatch repair, and more specifically one of its major players, the MSH3 protein.