Sentences with phrase «lab mice for»

Take lab mice for example.

Not exact matches

The Salk team therefore took human brain organoids that had been growing in lab dishes for 31 to 50 days and implanted them into mouse brains (more than 200 so far) from which they had removed a tiny bit of tissue to make room.

Automatic gear shifting for safer and more efficient wheelchairs; a technique for harnessing terahertz spectroscopy; «humanized» lab mice; and cheaper, more accurate malaria testing — meet this year's crop of Lemelson - M.I.T. collegiate student prize winners

Shukla and colleagues discovered that a small drug molecule called BX795, which is sold to labs for use in experiments, helped clear HSV - 1 infection in cultured human corneal cells, in donated human corneas, and in the corneas of mice infected with HSV - 1.

Insight into how this venom overwhelms lab mice could lead to an antidote for people who suffer excruciatingly painful, reportedly even fatal, centipede bites, an international research team reports the week...

For decades, wildlife documentaries have promoted the idea that Komodo dragons owe their success as predators to toxic bacteria in their saliva — a claim bolstered by a 2002 study reporting deaths among lab mice injected with their saliva.

Human norovirus can't be grown easily in a lab, and for this reason, the researchers choose to study it in mice.

«After 40 days, 40 percent of the mice who were treated using the microneedle patch survived and had no detectable remaining melanoma — compared to a zero percent survival rate for the control groups,» says Yanqi Ye, a Ph.D. student in Gu's lab and co-lead author of the paper.

Insight into how this venom overwhelms lab mice could lead to an antidote for people who suffer excruciatingly painful, reportedly even fatal, centipede bites, an international research team reports the week of January 22 in Proceedings of the National Academy of Sciences.

RECIPE FOR DISASTER Despite the lab mouse's much greater weight, chemistry gives this centipede the decisive advantage.

Would happy lab animals — rats, mice, even zebrafish — make for better experiments?

For example, mice have been given an extra color vision gene in the lab, and it has been shown that the protein manufactured by that gene expands the scope of their vision by enhancing their ability to see longer - wavelength light without any other changes in the brain.

Scientists had been searching in vain for such a gene since 1994 when Rockefeller University scientist Jeffery Friedman found that lab mice with a specific genetic mutation fail to produce leptin and as a result have uncontrollable appetites, and become huge.

Other researchers have used optogenetics to transmit artificial skin sensations into the brains of mice, but Ko plans to investigate other technologies to find a technique that's best suited for his lab's e-skin.

If a lab is studying the impact of stress on the growth of new neurons, for example, and then it lets mice exercise on a running wheel — which has been shown to spark neuron growth — the study could be jeopardized, Godbout says.

The lab mice that survived exposure to the bacteria and viruses of the pet store rodents had stronger immune systems, suggesting to Masopust and Jameson that such dirty mice might be better for testing the safety of vaccines and new drugs.

Concerned that the immune systems of clean mice might not be good proxies for the human immune system — no human is brought up in such clean conditions and fed such clean food — they housed lab mice with mice from a pet store.

The gut bacteria from the wild mice were fairly similar, but the microbiomes of the lab mice were significantly different, with fewer Bacteroidetes and Proteobacteria, for example.

Five years ago Viviana Gradinaru was slicing thin pieces of mouse brain in a neurobiology lab, slowly compiling images of the two - dimensional slivers for a three - dimensional computer rendering.

Two compounds already approved for use in humans increased the survival of lab mice even after they were exposed to radiation

Franco is also collaborating with a researcher who came to his lab seeking help in refining his mouse models for diabetes.

To better determine the role of specific chemoattractants in type III hypersensitivity, lead author Yoshishige Miyabe, MD, PhD, a research fellow in Luster's lab, used multiphoton intravital microscopy — an imaging technology pioneered for studies of immune cell movements in living animals by CIID investigator and co-author Thorsten Mempel, MD, PhD — to follow in real time the development of IC - induced arthritis in a mouse model of rheumatoid arthritis.

Instead of mice, it produces fluorescent zebrafish, which are easier for the undergraduate - staffed lab to handle, in part because they go from fertilization to free - swimming fish in a matter of days.

The ban is particularly problematic for researchers who need transgenic mice, which are often ordered from specialized labs.

To examine the role for endocannabinoids generated in peripheral organs in controlling the overeating of western diet, DiPatrizio and coauthor Donovan A. Argueta, a bioengineering Ph.D. student in his lab, used a mouse model of western diet - induced obesity (chronic exposure to high levels of sugars and fats).

In a lab near Deisseroth's office, Tye inserted a fiber - optic cable into a mouse's little brain at just the right spot, leaving enough slack for the animal to run around.

When Kyoto University researcher Shinya Yamanaka announced in 2006 that his lab had created iPS cells from mouse skin cells for the first time, biologists were stunned.

Coffin described how lab workers there had transplanted human prostate tumor cells into an immune - deficient lab mouse, a common procedure for procuring a colony of cells, or a human cell line, for further study.

The team also realized that Schreiweis had set up her mazes in a crowded lab full of computers, lab benches, and wall posters that the mice could turn to for clues about their location in the maze.

Enormous projects such as ENCODE (for humans and mice) or modENCODE (for other lab model systems, such as the fly Drosophila or the worm C. elegans) have been devoted to collecting these data in order to analyse and interpret them in the framework of genomic data and to form hypotheses about functions and relations.

For the current research project, Xia and his lab genetically modified mice so that their bodies wouldn't produce these sugars.

Back in the lab, the ecologists counted up the attacks by different predators — they can tell the nick of a bird's beak from the teeth marks of a mouse or the paired piercings of ant, for example.

Geneticist Jiří Forejt of the Czech Academy of Sciences» Institute of Molecular Genetics in Prague wasn't looking for it when he caught wild mice and bred them with lab mice to study diversity of immune system genes.

Because the amount of fibrosis in the liver is associated with a greater risk of death from NASH, Xiaobo Wang, PhD, associate research scientist in the Department of Medicine at CUMC working in the lab of Ira Tabas, MD, PhD, looked for ways to stop fibrosis in a mouse model of NASH.

In a paper published Sept. 21 in Cell, Harvard Medical School genetics professor Olivier Pourquié — whose lab discovered the segmentation clock 20 years ago — and colleagues report that they used mouse cells to reconstitute a stable version of this clockwork for the first time in a petri dish, leading to several new discoveries about where the clock is located, what makes it tick and how the vertebral column takes shape.

One example comes from the lab of Sheryl Moy, professor of psychiatry and director of the mouse behavioral phenotyping core at the University of North Carolina's Carolina Institute for Developmental Disabilities.

Mitchell's prior analysis examined lab studies that used an Alzheimer's lab mouse model that did not allow for the study of p - tau.

The causes of such unpredictable results, Harris said, can include bad ingredients in the lab, including contaminated and misidentified cell lines; poor research design, including insufficient numbers of mice in animal studies; statistical error and overreach, including «HARKing» (hypothesizing after the results are known), a push beyond the limits of the data; and funding pressures, which can lead scientists to hype or exaggerate their results to remain competitive for additional grant money.

Xia's lab screened approximately 7,000 metabolites for functional differences between sickle cell disease mice and controls.

One double - stranded RNA his lab tested was able to inactivate hepatitis B for more than a year without any apparent harm to the mice.

In a lab at the McGovern Institute for Brain Research at MIT, just a few black mice are brought forth for a demonstration.

For the first time, researchers have been able to grow, in a lab, both normal and primary cancerous prostate cells from a patient, and then implant a million of the cancer cells into a mouse to track how the tumor progresses.

Led by Rowitch lab postdoctoral fellow Anna Molofsky, MD, PhD, the researchers studied the spinal cord sensory motor circuit, which allows both mice and humans to react without thought — to jerk a limb away from something hot, for instance.

«Here we demonstrate that even mice who fully recover from the H1N1 influenza virus responsible for the previous pandemic (also called «swine flu») are later more susceptible to chemical toxins known to trigger Parkinson's in the lab.»

Short of reimagining the lab mouse, others say, investigators need strategies for monitoring how microbes might be influencing their small research subjects.

Earlier this year, his lab brought in its own «dirty» colony from a company that sells mice as food for zoo animals.

Mogil's lab developed pain grimace scales for rats and mice in 2006, and it discovered that mice experience pain when they see a familiar mouse suffering — a psychological phenomenon known as emotional contagion.

For a few thousand dollars per procedure, they can transfer mouse embryos from other labs into females from each colony, so that the mouse pups pick up the new microbiomes and can be compared to the original strains.

Eumorphia will develop a system for routing new mutant mice to labs that have the expertise to diagnose a given mutation's effects.

Many studies have shown that calorie restriction extends lifespan for lab organisms, from yeast through to worms, flies and mice.